| PubMed: | Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance. |
| PubMed: | Immobilization of sugars in supermacroporous cryogels for the purification of lectins by affinity chromatography. |
| PubMed: | Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells. |
| PubMed: | Safety, pharmacokinetics and sialic acid production after oral administration of N-acetylmannosamine (ManNAc) to subjects with GNE myopathy. |
| PubMed: | Production and characterization of active recombinant human factor II with consistent sialylation. |
| PubMed: | Clinical trials in minimal change disease. |
| PubMed: | Nutritional stimulation of commensal oral bacteria suppresses pathogens: the prebiotic concept. |
| PubMed: | Vibrational Signatures of Isomeric Lithiated N-acetyl-D-hexosamines by Gas-Phase Infrared Multiple-Photon Dissociation (IRMPD) Spectroscopy. |
| PubMed: | Identification of key genes involved in polysaccharide bioflocculant synthesis in Bacillus licheniformis. |
| PubMed: | Internalization of a novel, huge lectin from Ibacus novemdentatus (slipper lobster) induces apoptosis of mammalian cancer cells. |
| PubMed: | A sialic acid aldolase from Peptoclostridium difficile NAP08 with 4-hydroxy-2-oxo-pentanoate aldolase activity. |
| PubMed: | NANS-mediated synthesis of sialic acid is required for brain and skeletal development. |
| PubMed: | Protein engineering of a bacterial N-acyl-d-glucosamine 2-epimerase for improved stability under process conditions. |
| PubMed: | Identification of genes associated with the penetration activity of the human type of Edwardsiella tarda EdwGII through human colon epithelial cell monolayers. |
| PubMed: | Chronic administration of N-acetyl-D-mannosamine improves age-associated impairment of long-term potentiation in the senescence-accelerated mouse. |
| PubMed: | Characterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesis. |
| PubMed: | Crystal structure of product-bound complex of UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3. |
| PubMed: | Crystal structures and functional studies clarify substrate selectivity and catalytic residues for the unique orphan enzyme N-acetyl-D-mannosamine dehydrogenase. |
| PubMed: | First functional and mutational analysis of group 3 N-acetylneuraminate lyases from Lactobacillus antri and Lactobacillus sakei 23K. |
| PubMed: | Cloning and characterization of two different L-type lectin genes from the Chinese mitten crab Eriocheir sinensis. |
| PubMed: | Angiopoietin-like 4 based therapeutics for proteinuria and kidney disease. |
| PubMed: | Reaction mechanism of N-acetylneuraminic acid lyase revealed by a combination of crystallography, QM/MM simulation, and mutagenesis. |
| PubMed: | N-acetyl-D-mannosamine treatment alleviates age-related decline in place-learning ability in dogs. |
| PubMed: | The structure and immunomodulatory activity on intestinal epithelial cells of the EPSs isolated from Lactobacillus helveticus sp. Rosyjski and Lactobacillus acidophilus sp. 5e2. |
| PubMed: | Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida. |
| PubMed: | New N-acyl-D-glucosamine 2-epimerases from cyanobacteria with high activity in the absence of ATP and low inhibition by pyruvate. |
| PubMed: | Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. |
| PubMed: | Transforming growth factor beta receptor 2 (TGFBR2) changes sialylation in the microsatellite unstable (MSI) Colorectal cancer cell line HCT116. |
| PubMed: | Artificial and natural sialic acid precursors influence the angiogenic capacity of human umbilical vein endothelial cells. |
| PubMed: | Identification and characterization of cellobiose 2-epimerases from various aerobes. |
| PubMed: | Staining tumor cells with biotinylated ACL-I, a lectin isolated from the marine sponge, Axinella corrugata. |
| PubMed: | Characterization of a novel N-acetylneuraminate lyase from Staphylococcus carnosus TM300 and its application to N-acetylneuraminic acid production. |
| PubMed: | Functional assignment of gene AAC16202.1 from Rhodobacter capsulatus SB1003: new insights into the bacterial SDR sorbitol dehydrogenases family. |
| PubMed: | Metabolic monosaccharides altered cell responses to anticancer drugs. |
| PubMed: | A transposon site hybridization screen identifies galU and wecBC as important for survival of Yersinia pestis in murine macrophages. |
| PubMed: | Properties of BoAGE2, a second N-acetyl-D-glucosamine 2-epimerase from Bacteroides ovatus ATCC 8483. |
| PubMed: | New insights into human minimal change disease: lessons from animal models. |
| PubMed: | Designing a binding interface for control of cancer cell adhesion via 3D topography and metabolic oligosaccharide engineering. |
| PubMed: | Production of N-acetyl-D-neuraminic acid by use of an efficient spore surface display system. |
| PubMed: | New stabilized FastPrep-CLEAs for sialic acid synthesis. |
| PubMed: | Molecular characterization of a novel N-acetylneuraminate lyase from Lactobacillus plantarum WCFS1. |
| PubMed: | Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. |
| PubMed: | Comparison of phenotypic (Biolog System) and genotypic (random amplified polymorphic DNA-polymerase chain reaction, RAPD-PCR, and amplified fragment length polymorphism, AFLP) methods for typing Lactobacillus plantarum isolates from raw vegetables and fruits. |
| PubMed: | LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis. |
| PubMed: | Creatine kinase is a bacteriostatic factor with a lectin-like activity. |
| PubMed: | Targeting pro-invasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells. |
| PubMed: | UDP-GlcNAc2-epimerase regulates cell surface sialylation and ceramide-induced cell death in human malignant lymphoma. |
| PubMed: | Pasteurella multocida sialic acid aldolase: a promising biocatalyst. |
| PubMed: | A crosslinked inclusion body process for sialic acid synthesis. |
| PubMed: | Divergent evolution of function in the ROK sugar kinase superfamily: role of enzyme loops in substrate specificity. |
| PubMed: | Enhanced interferon-gamma secretion and antitumor activity of T-lymphocytes activated by dendritic cells loaded with glycoengineered myeloma antigens. |
| PubMed: | Modelling the reaction course of N-acetylneuraminic acid synthesis from N-acetyl-D-glucosamine--new strategies for the optimisation of neuraminic acid synthesis. |
| PubMed: | Purification, crystallization and preliminary X-ray diffraction studies of a putative UDP-N-acetyl-D-mannosamine dehydrogenase from Pyrococcus horikoshii OT3. |
| PubMed: | Metabolic expression of thiol-derivatized sialic acids on the cell surface and their quantitative estimation by flow cytometry. |
| PubMed: | Synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. |
| PubMed: | The central cavity from the (alpha/alpha)6 barrel structure of Anabaena sp. CH1 N-acetyl-D-glucosamine 2-epimerase contains two key histidine residues for reversible conversion. |
| PubMed: | Engineering of a sialic acid synthesis pathway in transgenic plants by expression of bacterial Neu5Ac-synthesizing enzymes. |
| PubMed: | Targeting glycosylation pathways and the cell cycle: sugar-dependent activity of butyrate-carbohydrate cancer prodrugs. |
| PubMed: | Engineering the sialic acid in organs of mice using N-propanoylmannosamine. |
| PubMed: | Preparation of a fluorous protecting group and its application to the chemoenzymatic synthesis of sialidase inhibitor. |
| PubMed: | Glycosylation is altered by ethanol in rat hippocampal cultured neurons. |
| PubMed: | Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology. |
| PubMed: | Accessibility of N-acyl-D-mannosamines to N-acetyl-D-neuraminic acid aldolase. |
| PubMed: | Increased expression of the selectin ligand sialyl-Lewis(x) by biochemical engineering of sialic acids. |
| PubMed: | Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronectin. |
| PubMed: | Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives. |
| PubMed: | Transport of N-acetyl-D-mannosamine and N-acetyl-D-glucosamine in Escherichia coli K1: effect on capsular polysialic acid production. |
| PubMed: | O-specific polysaccharide of the marine bacterium "Alteromonas marinoglutinosa" NCIMB 1770. |
| PubMed: | Biochemical engineering of the N-acyl side chain of sialic acid: biological implications. |
| PubMed: | Structure of the O16 antigen of Stenotrophomonas maltophilia. |
| PubMed: | Isolation and characterisation of a serum lectin from blue gourami, Trichogaster trichopterus (Pallus). |
| PubMed: | Synthesis of glycophostones: cyclic phosphonate analogues of biologically relevant sugars |
| PubMed: | Multiple N-acetyl neuraminic acid synthetase (neuB) genes in Campylobacter jejuni: identification and characterization of the gene involved in sialylation of lipo-oligosaccharide. |
| PubMed: | PCR identification of the group A Neisseria meningitidis gene in cerebrospinal fluid. |
| PubMed: | Alkaline biocatalysis for the direct synthesis of N-acetyl-D-neuraminic acid (Neu5Ac) from N-acetyl-D-glucosamine (GlcNAc). |
| PubMed: | Biosynthesis of KDN (2-keto-3-deoxy-D-glycero-D-galacto-nononic acid). Identification and characterization of a KDN-9-phosphate synthetase activity from trout testis. |
| PubMed: | Determination of different amino sugar 2'-epimerase activities by coupling to N-acetylneuraminate synthesis. |
| PubMed: | Uptake of N-acetyl-D-mannosamine: an essential intermediate in polysialic acid biosynthesis by Escherichia coli K92. |
| PubMed: | Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2-epimerase. |
| PubMed: | Regulation of capsular polysialic acid biosynthesis by N-acetyl-D-mannosamine, an intermediate of sialic acid metabolism. |
| PubMed: | Characterization of the gene cassette required for biosynthesis of the (alpha1-->6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis. |
| PubMed: | Purification and characterization of N-acetylneuraminate synthase from Escherichia coli K1-M12. |
| PubMed: | Structure of the O18 antigen from Acinetobacter baumannii. |
| PubMed: | An efficient process for production of N-acetylneuraminic acid using N-acetylneuraminic acid aldolase. |
| PubMed: | N-acetyl-D-neuraminic acid lyase generates the sialic acid for colominic acid biosynthesis in Escherichia coli K1. |
| PubMed: | Collectin in a non-mammalian species: isolation and characterization of mannan-binding protein (MBP) from chicken serum. |
| PubMed: | N-acetyl-D-neuraminic acid synthesis in Escherichia coli K1 occurs through condensation of N-acetyl-D-mannosamine and pyruvate. |
| PubMed: | Tritium labelling of amino sugars at C-2 by alkaline epimerization in tritiated water. |
| PubMed: | Chitosan-mediated stimulation of macrophage function. |
| PubMed: | The structure of the O-antigenic chain of the lipopolysaccharide of Rhizobium trifolii 4s. |
| PubMed: | The three-dimensional structure of N-acetylneuraminate lyase from Escherichia coli. |
| PubMed: | Identification of a genetic locus involved in the biosynthesis of N-acetyl-D-mannosamine, a precursor of the (alpha 2-->8)-linked polysialic acid capsule of serogroup B Neisseria meningitidis. |
| PubMed: | Purification and characterization of mannan-binding protein from mouse serum. |
| PubMed: | Purification and characterization of a mannose-specific lectin from Shallot (Allium ascalonicum) bulbs. |
| PubMed: | Detection, isolation and characterization of multiple lectins from the haemolymph of the cockroach Blaberus discoidalis. |
| PubMed: | Functional and structural identification of a new lectin activity of Borrelia recurrentis spirochetes. |
| PubMed: | Cholinergic and dopaminergic agents which inhibit a passive avoidance response attenuate the paradigm-specific increases in NCAM sialylation state. |
| PubMed: | Structures of the O1B and O1C lipopolysaccharide antigens of Escherichia coli. |
| PubMed: | Biosynthesis of a nonphysiological sialic acid in different rat organs, using N-propanoyl-D-hexosamines as precursors. |
| PubMed: | Neuronal ganglioside increases dependent on the neuron--glia interaction in primary culture. |
| PubMed: | Lack of cell density-dependent changes in gangliosides of rat primary culture neurons. |
| PubMed: | Conglutinin exhibits a complement-dependent enhancement of the respiratory burst of phagocytes stimulated by E. coli. |
| PubMed: | Suppression of human natural killer cell activity by amino sugars. |
| PubMed: | Purification and properties of N-acyl-D-mannosamine dehydrogenase from Flavobacterium sp. 141-8. |
| PubMed: | The anticonvulsant sodium valproate specifically induces the expression of a rat glial heat shock protein which is identified as the collagen type IV receptor. |
| PubMed: | Remodeling of a rat hepatocyte plasma membrane glycoprotein. De- and reglycosylation of dipeptidyl peptidase IV. |
| PubMed: | Binding properties of a mannose-specific lectin from the snowdrop (Galanthus nivalis) bulb. |
| PubMed: | Gangliosides, or sialic acid, antagonize ethanol intoxication. |
| PubMed: | Inhibition of yeast binding to mouse peritoneal macrophages by wheat germ agglutinin: a novel effect of the lectin on phagocytic cells. |
| PubMed: | Demonstration in human plasma of a lectin activity analogous to that of bovine conglutinin. |
| PubMed: | The molecular basis of the hyaluronic acid-mediated stimulation of granulocyte function. |
| PubMed: | Alteration of cerebral ganglioside metabolism in developing Snell dwarf mice. |
| PubMed: | A neuraminidase from Trypanosoma cruzi removes sialic acid from the surface of mammalian myocardial and endothelial cells. |
| PubMed: | CMP-sialic acid, the sole sialosyl donor, is intra-axonally transported. |
| PubMed: | Accumulation of N-acetylneuraminic acid (sialic acid) in human fibroblasts cultured in the presence of N-acetylmannosamine. |
| PubMed: | alpha-D-mannosidase forms in chicken liver. |
| PubMed: | N-acetyl-D-mannosamine analogues as potential inhibitors of sialic acid biosynthesis. |
| PubMed: | UDP-N-acetyl-D-mannosamine dehydrogenase from Escherichia coli. |
| PubMed: | The metabolism of sialic acid in cystic fibrosis. |
| PubMed: | Lectins of distinct specificity in Rhodnius prolixus interact selectively with Trypanosoma cruzi. |
| PubMed: | Kinetic characterization of N-acetyl-D-glucosamine kinase from rat liver and kidney. |
| PubMed: | The isolation and preliminary characterization of N-acetyl-D-glucosamine kinase from rat kidney and liver. |
| PubMed: | Enzymatic formation of uridine diphosphate N-acetyl-D-mannosamine. |
| PubMed: | Ia antigenic specificities are oligosaccharide in nature: hapten-inhibition studies. |
| PubMed: | Stimulation of HeLa-S3 cell aggregation by sugars related to cell membrane in rotation culture. |
| PubMed: | Distribution of neuraminidase and n-acetylneuraminate lyase activities among corynebacteria, mycobacteria, and nocardias. |
| PubMed: | Coupled-enzyme system for measuring viral neuraminidase activity. |
| PubMed: | Studies on N-acetylneuraminic acid aldolase. |
| PubMed: | [Purification and some properties of N-acetyl-D-mannosamine kinase from liver of normal rats and rats with thyrotoxicosis]. |
| PubMed: | [Activity of N-acetyl-D-mannosamine kinase of rat liver under some pathological conditions]. |
| PubMed: | Administration of N-acetyl-D-mannosamine to mammals. |
| PubMed: | STUDIES ON NITROGEN-CONTAINING SUGARS. I. SYNTHESIS OF N-ACETYL-D-MANNOSAMINE FROM 1-NITRO-1-DEOXY-D-MANNITOL PENTAACETATE. |
| PubMed: | Enzymatic phosphorylation of N-acetyl-D-mannosamine. |
| PubMed: | Preparation of N-acetyl-neuraminic acid from N-acetyl-D-mannosamine. |
| PubMed: | Enzymic synthesis of N-acetyl-D-mannosamine. |