epi-coprostanol
epi-cholestanol
 
Notes:
None found
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CAS Number: 516-95-0Picture of molecule3D/inchi
Other: 1380-69-4
FDA UNII: 87MLH50B7Q
Nikkaji Web: J14.274C
XlogP3-AA: 9.40 (est)
Molecular Weight: 388.67876000
Formula: C27 H48 O
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.0003391 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for epi-coprostanol usage levels up to:
 not for fragrance use.
 
Recommendation for epi-coprostanol flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 516-95-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 66066
National Institute of Allergy and Infectious Diseases: Data
 (3R,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Chemidplus: 0000516950
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References:
 (3R,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 66066
Pubchem (cas): 516-95-0
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C12978
HMDB (The Human Metabolome Database): HMDB01569
FooDB: FDB022694
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 ambergris
Search  PMC Picture
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Synonyms:
 cholestan-3-ol, (3-alpha,5-alpha)- (9CI)
epi-cholestanol
epidihydrocholesterin
(3R,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
3alpha-hydroxy-5alpha-cholestane
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Articles:
PubMed: Quantification of total cholesterol in human milk by gas chromatography.
PubMed: Steroid Biomarkers Revisited - Improved Source Identification of Faecal Remains in Archaeological Soil Material.
PubMed: Sterols indicate water quality and wastewater treatment efficiency.
PubMed: Sterols and Stanols Preserved in Pond Sediments Track Seabird Biovectors in a High Arctic Environment.
PubMed: Sterol ratios as a tool for sewage pollution assessment of river sediments in Serbia.
PubMed: Identifying avian sources of faecal contamination using sterol analysis.
PubMed: Microbial water quality and sedimentary faecal sterols as markers of sewage contamination in Kuwait.
PubMed: Determination of Geochemically Important Sterols and Triterpenols in Sediments Using Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry (UHPLC-MS/MS).
PubMed: Trace analysis of selected hormones and sterols in river sediments by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.
PubMed: Assessment of historical fecal contamination in Curitiba, Brazil, in the last 400 years using fecal sterols.
PubMed: An integrated evaluation of molecular marker indices and linear alkylbenzenes (LABs) to measure sewage input in a subtropical estuary (Babitonga Bay, Brazil).
PubMed: Baseline concentrations of faecal sterols and assessment of sewage input into different inlets of Admiralty Bay, King George Island, Antarctica.
PubMed: Evaluation of potential sewage contamination by fecal sterol biomarkers adsorbed in natural biofilms.
PubMed: Macrobenthos and multi-molecular markers as indicators of environmental contamination in a South American port (Mar del Plata, Southwest Atlantic).
PubMed: Climate impacts on human settlement and agricultural activities in northern Norway revealed through sediment biogeochemistry.
PubMed: Predicting the concentration range of unmonitored chemicals in wastewater-dominated streams and in run-off from biosolids-amended soils.
PubMed: Origin of fecal contamination in waters from contrasted areas: stanols as Microbial Source Tracking markers.
PubMed: Multi-molecular markers and metals as tracers of organic matter inputs and contamination status from an Environmental Protection Area in the SW Atlantic (Laranjeiras Bay, Brazil).
PubMed: Extreme variability of steroid profiles in cow feces and pig slurries at the regional scale: implications for the use of steroids to specify fecal pollution sources in waters.
PubMed: Ecosystem evolution of seal colony and the influencing factors in the 20th century on Fildes Peninsula, West Antarctica.
PubMed: Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions.
PubMed: Sedimentary records of sewage pollution using faecal markers in contrasting peri-urban shallow lakes.
PubMed: Distribution of sewage input in marine sediments around a maritime Antarctic research station indicated by molecular geochemical indicators.
PubMed: [NMR-spectroscopy-based metabonomic approach to analysis of Siwutang, a novel prescription, treated blood deficiency in mice].
PubMed: Sediments as a potential tool for assessment of sewage pollution in Barigüi River, Brazil.
PubMed: The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels.
PubMed: Determination of fecal sterols by gas chromatography-mass spectrometry with solid-phase extraction and injection-port derivatization.
PubMed: Assessment of fecal sterols in Barigui River sediments in Curitiba, Brazil.
PubMed: Identification and significance of sterols in MSW landfill leachate.
PubMed: Sterols: a tracer of organic matter in combined sewers.
PubMed: Evaluating potential applications of faecal sterols in distinguishing sources of faecal contamination from mixed faecal samples.
PubMed: Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment.
PubMed: Multivariate logistic regression for predicting total culturable virus presence at the intake of a potable-water treatment plant: novel application of the atypical coliform/total coliform ratio.
PubMed: Bacterial source tracking from diverse land use catchments by sterol ratios.
PubMed: Comparisons of water quality parameters from diverse catchments during dry periods and following rain events.
PubMed: Evaluation of ambrein and epicoprostanol for their antioxidant properties: protection against adriamycin-induced free radical toxicity.
PubMed: Microwave-assisted solvent extraction of solid matrices and subsequent detection of pharmaceuticals and personal care products (PPCPs) using gas chromatography-mass spectrometry.
PubMed: Interaction of the glycoalkaloid tomatine with DMPC and sterol monolayers studied by surface pressure measurements and Brewster angle microscopy.
PubMed: An efficient diethyl ether-based soxhlet protocol to quantify faecal sterols from catchment waters.
PubMed: Free Fatty acids and sterols in swine manure.
PubMed: Identifying the source, transport path and sinks of sewage derived organic matter.
PubMed: Tracking the origin of faecal pollution in surface water: an ongoing project within the European Union research programme.
PubMed: Use of fecal steroids to infer the sources of fecal indicator bacteria in the Lower Santa Ana River Watershed, California: sewage is unlikely a significant source.
PubMed: Application of comprehensive two-dimensional gas chromatography to the quantification of overlapping faecal sterols.
PubMed: Determination of faecal pollutants in Torrens and Patawalonga catchment waters in South Australia using faecal sterols.
PubMed: Structural features of sterols required to inhibit human sperm capacitation.
PubMed: Tracing sewage in the marine environment: altered signatures in Concepción Bay, Chile.
PubMed: Assay of microsomal oxysterol 7alpha-hydroxylase activity in the hamster liver by a sensitive method: in vitro modulation by oxysterols.
PubMed: Sedimentary 4-desmethyl sterols and n-alkanols in an eutrophic urban estuary, Capibaribe River, Brazil.
PubMed: Modulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase activities by steroids and physiological conditions in hamster.
PubMed: Method for simultaneous measurements of traces of heptadeuterated cholesterol and cholesterol by gas chromatography-mass spectrometry: application in humans.
PubMed: New method for determination of fecal sterols in urine using non-chlorinated solvents.
PubMed: Gas chromatographic analysis of resveratrol in plasma, lipoproteins and cells after in vitro incubations.
PubMed: Epicoprostanol found in adipocere from five human autopsies.
PubMed: Protection by epicoprostanol against hyperglycemia and insulitis in normal and diabetic rats.
PubMed: Features of cholesterol structure that regulate the clearance of chylomicron-like lipid emulsions.
PubMed: In vitro modulation of rat adipocyte ghost membrane fluidity by cholesterol oxysterols.
PubMed: Chromatographic separation of cholesterol in foods.
PubMed: Metabolic variables of cholesterol during squalene feeding in humans: comparison with cholestyramine treatment.
PubMed: Electron-capture gas chromatography as a sensitive method for measuring subnanogram amounts of cholesterol in saliva and urine.
PubMed: Intestinal cholesterol metabolism.
PubMed: Calcium-induced phase separation phenomena in multicomponent unsaturated lipid mixtures.
PubMed: Lipid acyl chain-dependent effects of sterols in Acholeplasma laidlawii membranes.
PubMed: Effect of sterol incorporation on head group separation in liposomes.
PubMed: Effect of cholesterol on phospholipid, RNA, and protein synthesis in Mycoplasma capricolum.
PubMed: Molecular packing in steroid-lecithin monolayers. IV. Mixed films of epicoprostanol with dipalmitoyl phosphatidylcholine.
PubMed: Coordinate regulation of unsaturated phospholipid, RNA, and protein synthesis in Mycoplasma capricolum by cholesterol.
PubMed: Reversed-phase thin layer chromatography of some common sterols.
PubMed: Comparative methods of quantifying fecal neutral sterols in rats and humans after intravenous [14C]-, [3H] or [2H]cholesterol labeling.
PubMed: Capillary gas-liquid chromatography of faecal free and esterified neutral sterols.
PubMed: Fecal steroids in diarrhea: IV. Cholera.
PubMed: The structure of mixed cholesterol-phospholipid monolayers spread at the air-water interface as probed by interactions with band 3 protein from erythrocyte membranes.
PubMed: Thin-layer and gas--liquid chromatographic identification of neutral steroids in human and rat feces.
PubMed: Identification and origins of neutral fecal sterols in adult Large White sows: occurrence of externally-secreted intestinal cholesterol.
PubMed: Gas chromatographic detection of the mycotoxin zearalenone in blood serum.
PubMed: Assessment of serum cholesterol by two methods: gas-liquid chromatography on a capillary column and chemical ionization-mass fragmentography with isotopic dilution of [3,4-13C] cholesterol as internal standard.
PubMed: Diet and sterol biohydrogenation in the rat: occurrence of epicoprostanol.
PubMed: Daily elimination of fecal neutral sterols by humans.
PubMed: Fecal steroids in diarrhea. I. Acute shigellosis.
PubMed: Sterol requirements of T-strain mycoplasmas.
PubMed: Esterification of injected epicoprostanol in a human subject.
PubMed: Stero-bile acids and bile alcohols. XCVII. Metabolism of epicoprostanol in the Japanese eel.
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