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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 159.7 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for xanthomicrol usage levels up to: | | | not for fragrance use.
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| Recommendation for xanthomicrol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 5-hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxychromen-4-one |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 73207 |
| Pubchem (cas): | 16545-23-6 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4H-1- | benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxy- | | 4',5- | dihydroxy-6,7,8-trimethoxyflavone | | 5- | hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one | | 5- | hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxychromen-4-one |
Articles:
| PubMed: | Characterization of bioactive constituents from the gum resin of Gardenia lucida and its pharmacological potential. |
| PubMed: | Pharmacokinetics of calycopterin and xanthmicrol, two polymethoxylated hydroxyflavones with anti-angiogenic activities from Dracocephalum kotschyi Bioss. |
| PubMed: | A new bioactive monoterpene-flavonoid from Satureja khuzistanica. |
| PubMed: | Flavonoids from Sideritis Species: Human Monoamine Oxidase (hMAO) Inhibitory Activities, Molecular Docking Studies and Crystal Structure of Xanthomicrol. |
| PubMed: | Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies. |
| PubMed: | Overproduction of valuable methoxylated flavones in induced tetraploid plants of Dracocephalum kotschyi Boiss. |
| PubMed: | Xanthomicrol: a comprehensive review of its chemistry, distribution, biosynthesis and pharmacological activity. |
| PubMed: | Antiangiogenic activity of xanthomicrol and calycopterin, two polymethoxylated hydroxyflavones in both in vitro and ex vivo models. |
| PubMed: | Identification and quantification of leaf surface flavonoids in wild-growing populations of Dracocephalum kotschyi by LC-DAD-ESI-MS. |
| PubMed: | Flavonoids of Dikamali: A phytochemical reinvestigation. |
| PubMed: | Antiproliferative activity of flavonoids: influence of the sequential methoxylation state of the flavonoid structure. |
| PubMed: | Phytochemical investigation and biological studies of Bombax malabaricum flowers. |
| PubMed: | The recurvatianes: a suite of oxygenated guaiane sesquiterpenes from Perezia recurvata. |
| PubMed: | Sonoran propolis: chemical composition and antiproliferative activity on cancer cell lines. |
| PubMed: | In vivo anti-inflammatory and antinociceptive activity evaluation of phenolic compounds from Sideritis stricta. |
| PubMed: | Relaxant effect of xanthomicrol and 3alpha-angeloyloxy-2alpha-hydroxy-13,14z-dehydrocativic acid from Brickellia paniculata on rat uterus. |
| PubMed: | Xanthomicrol is the main cytotoxic component of Dracocephalum kotschyii and a potential anti-cancer agent. |
| PubMed: | Bioactive constituents from Dracocephalum subcapitatum (O. Kuntze) Lipsky. |
| PubMed: | Antiplatelet activity of Varthemia iphionoides. |
| PubMed: | Chemical profiling of Ocimum americanum using external flavonoids. |
| PubMed: | Inhibitory effect of xanthomicrol and 3 alpha-angeloyloxy-2 alpha-hydroxy-13,14Z-dehydrocativic acid from Brickellia paniculata on the contractility of guinea-pig ileum. |
| PubMed: | Distribution of 8-oxygenated leaf-surface flavones in the genus Ocimum. |
| PubMed: | Genetic diversity of Ocimum gratissimum L. based on volatile oil constituents, flavonoids and RAPD markers. |
| PubMed: | Inhibition of prostaglandin E2 and leukotriene C4 in mouse peritoneal macrophages and thromboxane B2 production in human platelets by flavonoids from Stachys chrysantha and Stachys candida. |
| PubMed: | Pharmacological effects of selected flavonoids on rat isolated ileum: structure-activity relationship. |
| PubMed: | Inhibition of sheep platelet arachidonate metabolism by flavonoids from Spanish and Indian medicinal herbs. |
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