maysin
 
Notes:
None found
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CAS Number: 70255-49-1Picture of molecule3D/inchi
FDA UNII: 01O8RT377Y
XlogP3-AA: -0.30 (est)
Molecular Weight: 576.50896000
Formula: C27 H28 O14
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 167.9 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for maysin usage levels up to:
 not for fragrance use.
 
Recommendation for maysin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 70698181
National Institute of Allergy and Infectious Diseases: Data
 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2R,3S,4S,6S)-4-hydroxy-6-methyl-5-oxo-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]chromen-4-one
Chemidplus: 0070255491
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References:
 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2R,3S,4S,6S)-4-hydroxy-6-methyl-5-oxo-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]chromen-4-one
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 70698181
Pubchem (cas): 70255-49-1
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
HMDB (The Human Metabolome Database): HMDB37419
FooDB: FDB016466
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 zea mays stigma
Search Trop  Picture
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Synonyms:
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2R,3S,4S,6S)-4-hydroxy-6-methyl-5-oxo-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]chromen-4-one
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Articles:
PubMed: Genome-Wide Association and Metabolic Pathway Analysis of Corn Earworm Resistance in Maize.
PubMed: Corn silk extract improves benign prostatic hyperplasia in experimental rat model.
PubMed: Maydis Stigma Elicits Analgesia and Blocks Edema in Mice and Inhibits Inflammation in Macrophages.
PubMed: Corn silk maysin ameliorates obesity in vitro and in vivo via suppression of lipogenesis, differentiation, and function of adipocytes.
PubMed: Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model.
PubMed: High maysin corn silk extract reduces body weight and fat deposition in C57BL/6J mice fed high-fat diets.
PubMed: Corn silk extract improves cholesterol metabolism in C57BL/6J mouse fed high-fat diets.
PubMed: Identification and Characterization of Maize salmon silks Genes Involved in Insecticidal Maysin Biosynthesis.
PubMed: Maize Domestication and Anti-Herbivore Defences: Leaf-Specific Dynamics during Early Ontogeny of Maize and Its Wild Ancestors.
PubMed: Traditionally used medicinal plants against uncomplicated urinary tract infections: Are unusual, flavan-4-ol- and derhamnosylmaysin derivatives responsible for the antiadhesive activity of extracts obtained from stigmata of Zea mays L. against uropathogenic E. coli and Benzethonium chloride as frequent contaminant faking potential antibacterial activities?
PubMed: Protective effect of centipedegrass against Aβ oligomerization and Aβ-mediated cell death in PC12 cells.
PubMed: Corn silk maysin induces apoptotic cell death in PC-3 prostate cancer cells via mitochondria-dependent pathway.
PubMed: Centipedegrass extract induces apoptosis through the activation of caspases and the downregulation of PI3K/Akt and MAPK phosphorylation in leukemia cells.
PubMed: Neuroprotective effects of corn silk maysin via inhibition of H2O2-induced apoptotic cell death in SK-N-MC cells.
PubMed: Molecular mechanism of apoptosis induction in skin cancer cells by the centipedegrass extract.
PubMed: Immunostimulating activity of maysin isolated from corn silk in murine RAW 264.7 macrophages.
PubMed: Identification of a bifunctional maize C- and O-glucosyltransferase.
PubMed: Centipede grass exerts anti-adipogenic activity through inhibition of C/EBPβ, C/EBPα, and PPARγ expression and the AKT signaling pathway in 3T3-L1 adipocytes.
PubMed: Expression of flavonoid 3'-hydroxylase is controlled by P1, the regulator of 3-deoxyflavonoid biosynthesis in maize.
PubMed: Divergence of gene regulation through chromosomal rearrangements.
PubMed: Identification of multiple ear-colonizing insect and disease resistance in CIMMYT maize inbred lines with varying levels of silk maysin.
PubMed: Resistance to Spodoptera frugiperda (Lepidoptera: Noctuidae) and Euxesta stigmatias (Diptera: Ulidiidae) in sweet corn derived from exogenous and endogenous genetic systems.
PubMed: Inhibition of non-enzymatic glycation by silk extracts from a Mexican land race and modern inbred lines of maize (Zea mays).
PubMed: Quantitative trait loci for maysin synthesis in maize (Zea mays L.) lines selected for high silk maysin content.
PubMed: Expression of a maize Myb transcription factor driven by a putative silk-specific promoter significantly enhances resistance to Helicoverpa zea in transgenic maize.
PubMed: Transformation of maize with the p1 transcription factor directs production of silk maysin, a corn earworm resistance factor, in concordance with a hierarchy of floral organ pigmentation.
PubMed: Association analysis of candidate genes for maysin and chlorogenic acid accumulation in maize silks.
PubMed: Lost P1 allele in sh2 sweet corn: quantitative effects of p1 and a1 genes on concentrations of maysin, apimaysin, methoxymaysin, and chlorogenic acid in maize silk.
PubMed: Salmon silk genes contribute to the elucidation of the flavone pathway in maize (Zea mays L.).
PubMed: Effect of maysin on wild-type, deltamethrin-resistant, and Bt-resistant Helicoverpa armigera (Lepidoptera: Noctuidae).
PubMed: A maize QTL for silk maysin levels contains duplicated Myb-homologous genes which jointly regulate flavone biosynthesis.
PubMed: The genetic basis of C-glycosyl flavone B-ring modification in maize (Zea mays L.) silks.
PubMed: Effect of husk characters on resistance to corn earworm (Lepidoptera: Noctuidae) in high-maysin maize populations.
PubMed: The biological basis of epistasis between quantitative trait loci for flavone and 3-deoxyanthocyanin synthesis in maize (Zea mays L.).
PubMed: Restriction fragment length polymorphism markers associated with silk maysin, antibiosis to corn earworm (Lepidoptera: Noctuidae) larvae, in a dent and sweet corn cross.
PubMed: Conventional resistance of experimental maize lines to corn earworm (Lepidoptera: Noctuidae), fall armyworm (Lepidoptera: Noctuidae), southwestern corn borer (Lepidoptera: Crambidae), and sugarcane borer (Lepidoptera: Crambidae).
PubMed: Genetic mechanisms underlying apimaysin and maysin synthesis and corn earworm antibiosis in maize (Zea mays L.).
PubMed: Quantitative trait loci and metabolic pathways.
PubMed: Quantitative trait loci and metabolic pathways: genetic control of the concentration of maysin, a corn earworm resistance factor, in maize silks.
PubMed: Biochemical activity of centipedegrass against fall armyworm larvae.
PubMed: Roles of amino acids, protein, and fiber in leaf-feeding resistance of corn to the fall armyworm.
PubMed: Effects of cotton condensed tannin, maysin (Corn) and pinitol (soybeans) onHeliothis zea growth and development.
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