oleacein
 
Notes:
None found
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CAS Number: 149183-75-5Picture of molecule3D/inchi
Nikkaji Web: J948.172I
XlogP3-AA: 1.10 (est)
Molecular Weight: 320.34160000
Formula: C17 H20 O6
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 954.7 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for oleacein usage levels up to:
 not for fragrance use.
 
Recommendation for oleacein flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 15553186
National Institute of Allergy and Infectious Diseases: Data
 2-(3,4-dihydroxyphenyl)ethyl (Z,3S)-4-formyl-3-(2-oxoethyl)hex-4-enoate
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References:
 2-(3,4-dihydroxyphenyl)ethyl (Z,3S)-4-formyl-3-(2-oxoethyl)hex-4-enoate
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 15553186
Pubchem (cas): 149183-75-5
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): HMDB37321
FooDB: FDB016341
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 jasminum grandiflorum
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 olea europaea
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Synonyms:
2-(3,4-dihydroxyphenyl)ethyl (Z,3S)-4-formyl-3-(2-oxoethyl)hex-4-enoate
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Articles:
PubMed: Quantitation of Oleuropein and Related Phenolics in Cured Spanish-Style Green, California-Style Black Ripe, and Greek-Style Natural Fermentation Olives.
PubMed: Simple and efficient sustainable semi-synthesis of oleacein [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate] as potential additive for edible oils.
PubMed: Oleacein may inhibit destabilization of carotid plaques from hypertensive patients. Impact on high mobility group protein-1.
PubMed: Soft-MS and Computational Mapping of Oleuropein.
PubMed: Biofortification (Se): Does it increase the content of phenolic compounds in virgin olive oil (VOO)?
PubMed: Antimicrobial activity of Olea europaea Linné extracts and their applicability as natural food preservative agents.
PubMed: Direct study of minor extra-virgin olive oil components without any sample modification.1H NMR multisupression experiment: A powerful tool.
PubMed: An integrated process for the recovery of high added-value compounds from olive oil using solid support free liquid-liquid extraction and chromatography techniques.
PubMed: Quantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography-tandem mass spectrometry.
PubMed: Phenolic compounds of 'Galega Vulgar' and 'Cobrançosa' olive oils along early ripening stages.
PubMed: Oil quality parameters and quantitative measurement of major secoiridoid derivatives in Neb Jmel olive oil from various Tunisian origins using qNMR.
PubMed: Oleacein enhances anti-inflammatory activity of human macrophages by increasing CD163 receptor expression.
PubMed: Quantity and quality of secoiridoids and lignans in extra virgin olive oils: the effect of two- and three-way decanters on Leccino and Raggiola olive cultivars.
PubMed: Extraction of phenolic compounds from virgin olive oil by deep eutectic solvents (DESs).
PubMed: Oleocanthal Modulates Estradiol-Induced Gene Expression Involving Estrogen Receptor α.
PubMed: Quantitative Determination of Secoiridoids and Phenylpropanoids in Different Extracts of Ligustrum Vulgare L. Leaves by a Validated HPTLC-Photodensitometry Method.
PubMed: Oleacein. translation from Mediterranean diet to potential antiatherosclerotic drug.
PubMed: Quantitative analysis of pungent and anti-inflammatory phenolic compounds in olive oil by capillary electrophoresis.
PubMed: Components of a standardised olive leaf dry extract (Ph. Eur.) promote hypothiocyanite production by lactoperoxidase.
PubMed: One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor.
PubMed: Inhibition of human neutrophils NEP activity, CD11b/CD18 expression and elastase release by 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde, oleacein.
PubMed: Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers.
PubMed: Oleuropein and oleacein may restore biological functions of endothelial progenitor cells impaired by angiotensin II via activation of Nrf2/heme oxygenase-1 pathway.
PubMed: Direct measurement of oleocanthal and oleacein levels in olive oil by quantitative (1)H NMR. Establishment of a new index for the characterization of extra virgin olive oils.
PubMed: Angiotensin converting enzyme (ACE) inhibitors from Jasminum azoricum and Jasminum grandiflorum.
PubMed: Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea.
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