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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 268.4 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for methyl rosmarinate usage levels up to: | | | not for fragrance use.
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| Recommendation for methyl rosmarinate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6479915 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | methyl (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoate |
References:
| | methyl (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 6479915 |
| Pubchem (cas): | 99353-00-1 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | methyl (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoate |
Articles:
| PubMed: | Nepeta deflersiana attenuates isoproterenol-induced myocardial injuries in rats: Possible involvement of oxidative stress, apoptosis, inflammation through nuclear factor (NF)-κB downregulation. |
| PubMed: | Anti-hepatitis, antioxidant activities and bioactive compounds of Dracocephalum heterophyllum extracts. |
| PubMed: | Carbonic Anhydrase and Urease Inhibitory Potential of Various Plant Phenolics Using in vitro and in silico Methods. |
| PubMed: | Antioxidant activity of rosmarinic acid and its principal metabolites in chemical and cellular systems: Importance of physico-chemical characteristics. |
| PubMed: | Bioassay-Guided Isolation and Identification of Xanthine Oxidase Inhibitory Constituents from the Leaves of Perilla frutescens. |
| PubMed: | Phtytochemical Studies and Quantitative HPLC Analysis of Rosmarinic Acid and Luteolin 5-O-β-D-Glucopyranoside on Thymus praecox subsp. grossheimii var. grossheimii. |
| PubMed: | [Chemical constituents of Hyptis rhomboidea and their antifungal activity]. |
| PubMed: | Rosmarinic Acid and Its Methyl Ester as Antimicrobial Components of the Hydromethanolic Extract of Hyptis atrorubens Poit. (Lamiaceae). |
| PubMed: | Impact of fatty acid chain length of rosmarinate esters on their antimicrobial activity against Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263. |
| PubMed: | [Chemical constituents of Salvia chinensis]. |
| PubMed: | Antibacterial activity-guided purification and identification of a novel C-20 oxygenated ent-kaurane from Rabdosia serra (MAXIM.) HARA. |
| PubMed: | Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1 (MMP-1). |
| PubMed: | Clerodendranoic acid, a new phenolic acid from Clerodendranthus spicatus. |
| PubMed: | Polyphenolic profile and biological activity of Salvia splendens leaves. |
| PubMed: | An unusual caffeic acid derived bicyclic [2.2.2] octane lignan and other constituents from Cordia rufescens. |
| PubMed: | In silico and in vitro immunomodulatory studies on compounds of Lindelofia stylosa. |
| PubMed: | Antioxidant, anti-glycation and anti-inflammatory activities of phenolic constituents from Cordia sinensis. |
| PubMed: | Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase. |
| PubMed: | [Chemical study on ethyl acetate portion of Ehretia thyrsiflora, boraginaceae species of Kudingcha]. |
| PubMed: | Determination of polyphenolic compounds in commercial herbal drugs and spices from Lamiaceae: thyme, wild thyme and sweet marjoram by chromatographic techniques. |
| PubMed: | Determination of water-soluble polyphenolic compounds in commercial herbal teas from Lamiaceae: peppermint, melissa, and sage. |
| PubMed: | Three angiotensin-converting enzyme inhibitors from Rabdosia coetsa. |
| PubMed: | A New Rosmarinic Acid Derivative from Isodon oresbius. |
| PubMed: | Isolation and lipoxygenase-inhibition studies of phenolic constituents from Ehretia obtusifolia. |
| PubMed: | Antioxidative constituents from Lycopus lucidus. |
| PubMed: | [Separation and quantitative determination of seven aqueous depsides in Salvia miltiorrhiza by HPTLC scanning]. |
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