saussurea lactone, 23527-07-3

Articles:

PubMed:	Anti-allergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments.
PubMed:	Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.
PubMed:	Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway.
PubMed:	Bioassay-guided isolation of dehydrocostus lactone from Saussurea lappa: A new targeted cytosolic thioredoxin reductase anticancer agent.
PubMed:	"Click" reaction mediated synthesis of costunolide and dehydrocostuslactone derivatives and evaluation of their cytotoxic activity.
PubMed:	Costunolide induces G1/S phase arrest and activates mitochondrial-mediated apoptotic pathways in SK-MES 1 human lung squamous carcinoma cells.
PubMed:	A new sesquiterpenoid from Saussurea lappa roots.
PubMed:	Bioactivity-Guided Isolation of Antiproliferative Sesquiterpene Lactones from Centaurea solstitialis L. ssp. solstitialis.
PubMed:	The Genome-Wide Expression Profile of Saussurea lappa Extract on House Dust Mite-Induced Atopic Dermatitis in Nc/Nga Mice.
PubMed:	Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone.
PubMed:	Sesquiterpene lactones derived from Saussurea lappa induce apoptosis and inhibit invasion and migration in neuroblastoma cells.
PubMed:	Alantolactone from Saussurea lappa Exerts Antiinflammatory Effects by Inhibiting Chemokine Production and STAT1 Phosphorylation in TNF-α and IFN-γ-induced in HaCaT cells.
PubMed:	Estimation of Costunolide and Dehydrocostus Lactone in Saussurea lappa and its Polyherbal Formulations followed by their Stability Studies Using HPLC-DAD.
PubMed:	Inhibition of Wnt/β-Catenin Pathway by Dehydrocostus Lactone and Costunolide in Colon Cancer Cells.
PubMed:	UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa.
PubMed:	Dehydrocostuslactone inhibits LPS-induced inflammation by p38MAPK-dependent induction of hemeoxygenase-1 in vitro and improves survival of mice in CLP-induced sepsis in vivo.
PubMed:	Saussurea lappa Clarke-Derived Costunolide Prevents TNF α -Induced Breast Cancer Cell Migration and Invasion by Inhibiting NF- κ B Activity.
PubMed:	Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, India.
PubMed:	Pulchellamin G, an amino acid-sesquiterpene lactone, from Saussurea pulchella suppresses lipopolysaccharide-induced inflammatory responses via heme oxygenase-1 expression in murine peritoneal macrophages.
PubMed:	A note on Aucklandia lappa.
PubMed:	Studies on lymphangiogenesis inhibitors from Korean and Japanese crude drugs.
PubMed:	Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells.
PubMed:	[Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots].
PubMed:	NF-κB dependent anti-inflammatory activity of chlorojanerin isolated from Saussurea heteromalla.
PubMed:	Santamarin, a sesquiterpene lactone isolated from Saussurea lappa, represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells.
PubMed:	Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of Akt/GSK-3β and mTOR signaling pathways.
PubMed:	Essential oil composition and larvicidal activity of Saussurea lappa roots against the mosquito Aedes albopictus (Diptera: Culicidae).
PubMed:	The hexane extract of Saussurea lappa and its active principle, dehydrocostus lactone, inhibit prostate cancer cell migration.
PubMed:	Matrix solid-phase dispersion extraction coupled with HPLC-diode array detection method for the analysis of sesquiterpene lactones in root of Saussurea lappa C.B.Clarke.
PubMed:	Sesquiterpene lactones from Saussurea involucrata.
PubMed:	Antitrypanosomal sesquiterpene lactones from Saussurea costus.
PubMed:	Dehydrocostus lactone prevents mitochondrial dysfunction in osteoblastic MC3T3-E1 cells.
PubMed:	A new sesquiterpene and other constituents from Saussurea lappa root.
PubMed:	Quantitative analysis of costunolide and dehydrocostuslactone in rat plasma by ultraperformance liquid chromatography-electrospray ionization-mass spectrometry.
PubMed:	[Lactone constituents of Saussurea involucrata].
PubMed:	Evaluation of anticancer activity of dehydrocostuslactone in vitro.
PubMed:	Dehydrocostuslactone, a medicinal plant-derived sesquiterpene lactone, induces apoptosis coupled to endoplasmic reticulum stress in liver cancer cells.
PubMed:	Isolation of betulinic acid, its methyl ester and guaiane sesquiterpenoids with protein tyrosine phosphatase 1B inhibitory activity from the roots of Saussurea lappa C.B.Clarke.
PubMed:	Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa.
PubMed:	A new sesquiterpene lactone from the roots of Saussurea lappa: structure-anticancer activity study.
PubMed:	Sulfonated guaianolides from Saussurea lappa.
PubMed:	Guaiane sesquiterpene lactones and amino acid-sesquiterpene lactone conjugates from the aerial parts of Saussurea pulchella.
PubMed:	The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme.
PubMed:	Two new butenolide derivatives from Saussurea katochaete.
PubMed:	A new sesquiterpene lactone with sulfonic acid group from Saussurea lappa.
PubMed:	The alpha-methylene-gamma-butyrolactone moiety in dehydrocostus lactone is responsible for cytoprotective heme oxygenase-1 expression through activation of the nuclear factor E2-related factor 2 in HepG2 cells.
PubMed:	Sesquiterpene lactones from Saussurea alata.
PubMed:	Saussurea costus: botanical, chemical and pharmacological review of an ayurvedic medicinal plant.
PubMed:	PTP1B inhibitors from Saussrurea lappa.
PubMed:	Cytotoxic sesquiterpene lactones from Saussurea calcicola.
PubMed:	Two new sesquiterpene lactones with the sulfonic acid group from Saussurea lappa.
PubMed:	In vitro cytotoxicity of Mokko lactone in human leukemia HL-60 cells: induction of apoptotic cell death by mitochondrial membrane potential collapse.
PubMed:	Dehydrocostus lactone enhances tumor necrosis factor-alpha-induced apoptosis of human leukemia HL-60 cells.
PubMed:	Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone, on the viability of leukocyte cancer cell lines.
PubMed:	Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells.
PubMed:	Cytotoxic sesquiterpene lactones from the root of Saussurea lappa.
PubMed:	Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inflammation.
PubMed:	Effects of sesquiterpenes and amino acid-sesquiterpene conjugates from the roots of Saussurea lappa on inducible nitric oxide synthase and heat shock protein in lipopolysaccharide-activated macrophages.
PubMed:	Costunolide triggers apoptosis in human leukemia U937 cells by depleting intracellular thiols.
PubMed:	Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway.
PubMed:	Germacrenes from fresh costus roots.
PubMed:	In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa.
PubMed:	Inhibition of LPS-induced NO production and NF-kappaB activation by a sesquiterpene from Saussurea lappa.
PubMed:	A sesquiterpene, dehydrocostus lactone, inhibits the expression of inducible nitric oxide synthase and TNF-alpha in LPS-activated macrophages.
PubMed:	Inhibitory effect of sesquiterpene lactones from Saussurea lappa on tumor necrosis factor-alpha production in murine macrophage-like cells.
PubMed:	Effect of dehydrocostus lactone and costunolide from Saussurea root on the central nervous system in mice.
PubMed:	Costunolide and dehydrocostus lactone as inhibitors of killing function of cytotoxic T lymphocytes.
PubMed:	Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells.
PubMed:	Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix.
PubMed:	Allergic contact dermatitis to costus: removal of haptens with polymers.
PubMed:	Pharmacological investigations on Saussurea lappa (Clarke).