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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 0.001253 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Licoricidin >98%
Odor: characteristic Use: Licoricidin is a natural flavonoid compound found in several plants. |
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for licoricidin usage levels up to: | | | not for fragrance use.
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| Recommendation for licoricidin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 480865 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | 4-[(3R)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol |
| Chemidplus: | 0030508271 |
References:
| | 4-[(3R)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 480865 |
| Pubchem (cas): | 30508-27-1 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4-((R)-7- | hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-3-yl)-2-((E)-3-methyl-but-2-enyl)-benzene-1,3-diol | | 4-[(3R)-7- | hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol |
Articles:
| PubMed: | Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. |
| PubMed: | Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy. |
| PubMed: | Isolation and characterization of antimutagenic components ofGlycyrrhiza asperaagainstN-methyl-N-nitrosourea. |
| PubMed: | Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS. |
| PubMed: | Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma. |
| PubMed: | Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts. |
| PubMed: | Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells. |
| PubMed: | Metabolites identification of bioactive licorice compounds in rats. |
| PubMed: | Prenylated polyphenolic compounds from Glycyrrhiza iconica and their antimicrobial and antioxidant activities. |
| PubMed: | Structures of new phenolics isolated from licorice, and the effectiveness of licorice phenolics on vancomycin-resistant Enterococci. |
| PubMed: | Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis. |
| PubMed: | Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice. |
| PubMed: | Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. |
| PubMed: | Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification. |
| PubMed: | Licorice and its potential beneficial effects in common oro-dental diseases. |
| PubMed: | Modulation of matrix metalloproteinase and cytokine production by licorice isolates licoricidin and licorisoflavan A: potential therapeutic approach for periodontitis. |
| PubMed: | Hexane-ethanol extract of Glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of DU145 human prostate cancer cells. |
| PubMed: | Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus. |
| PubMed: | Antinephritis and radical scavenging activity of prenylflavonoids. |
| PubMed: | Anti-Helicobacter pylori flavonoids from licorice extract. |
| PubMed: | Antibacterial compounds of licorice against upper airway respiratory tract pathogens. |
| PubMed: | Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus. |
| PubMed: | Inhibition of lysoPAF acetyltransferase activity by components of licorice root. |
| PubMed: | Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by flavonoids from licorice roots and 4-arylcoumarins. |
| PubMed: | The chemical studies on the oriental plant drugs. XIX. Some new constituents of licorice root. 1. The structure of licoricidin. |
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