casuarinin
 
Notes:
None found
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CAS Number: 79786-01-9Picture of molecule3D/inchi
XlogP3-AA: 1.20 (est)
Molecular Weight: 936.65336000
Formula: C41 H28 O26
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 1.067 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for casuarinin usage levels up to:
 not for fragrance use.
 
Recommendation for casuarinin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 442673
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0079786019
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References:
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 442673
Pubchem (cas): 79786-01-9
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
KEGG (GenomeNet): C10213
HMDB (The Human Metabolome Database): HMDB30632
FooDB: FDB002533
VCF-Online: VCF Volatile Compounds in Food
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 corylus heterophylla
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 terminalia arjuna bark
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Synonyms:
neovescalin, 11-de(6-carboxy-2,3,4-trihydroxyphenyl)-, cyclic 16,18-(4,4',5,5',6,6'-hexahydroxy(1,1-biphenyl)-2,2'-dicarboxylate) 17-(3,4,5-trihydroxybenzoate), (15beta)-
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Articles:
PubMed: Variability in Foliar Ellagitannins of Hippophaë rhamnoides L. and Identification of a New Ellagitannin, Hippophaenin C.
PubMed: Protective effect of casuarinin against glutamate-induced apoptosis in HT22 cells through inhibition of oxidative stress-mediated MAPK phosphorylation.
PubMed: Impact of extraction techniques on antioxidant capacities and phytochemical composition of polyphenol-rich extracts.
PubMed: Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures.
PubMed: Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers.
PubMed: Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in HepG2 cells.
PubMed: High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-Glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae).
PubMed: Determination of phenolic compounds and antioxidant activity in leaves from wild Rubus L. species.
PubMed: Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex.
PubMed: Extracts and compounds with anti-diabetic complications and anti-cancer activity from Castanea mollissina Blume (Chinese chestnut).
PubMed: Hepatitis C virus inhibitory hydrolysable tannins from the fruits of Terminalia chebula.
PubMed: Chemical constituents from Melastoma dodecandrum and their inhibitory activity on interleukin-8 production in HT-29 cells.
PubMed: Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study.
PubMed: C-glucosidic ellagitannins from Lythri herba (European Pharmacopoeia): chromatographic profile and structure determination.
PubMed: Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells.
PubMed: Casuarinin suppresses TARC/CCL17 and MDC/CCL22 production via blockade of NF-κB and STAT1 activation in HaCaT cells.
PubMed: Casuarinin suppresses TNF-α-induced ICAM-1 expression via blockade of NF-κB activation in HaCaT cells.
PubMed: Fatty acid synthase inhibitors from Geum japonicum Thunb. var. chinense.
PubMed: Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells.
PubMed: Anticancer and antioxidant tannins from Pimenta dioica leaves.
PubMed: Casuarinin from the bark of Terminalia arjuna induces apoptosis and cell cycle arrest in human breast adenocarcinoma MCF-7 cells.
PubMed: Induction of cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells by casuarinin from the bark of Terminalia arjuna Linn.
PubMed: Casuarinin protects cultured MDCK cells from hydrogen peroxide-induced oxidative stress and DNA oxidative damage.
PubMed: Determination of hydrolyzable tannins in the fruit of Terminalia chebula Retz. by high-performance liquid chromatography and capillary electrophoresis.
PubMed: Antiherpes simplex virus type 2 activity of casuarinin from the bark of Terminalia arjuna Linn.
PubMed: Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography--electrospray ionisation mass spectrometry.
PubMed: Induction of apoptosis by hydrolyzable tannins from Eugenia jambos L. on human leukemia cells.
PubMed: Suppression of lipopolysaccharide-induced nuclear factor-kappaB activity by theaflavin-3,3'-digallate from black tea and other polyphenols through down-regulation of IkappaB kinase activity in macrophages.
PubMed: Inhibitory effects of hydrolyzable tannins from Melastoma dodecandrum Lour. on nitric oxide production by a murine macrophage-like cell line, RAW264.7, activated with lipopolysaccharide and interferon-gamma.
PubMed: Carbonic anhydrase inhibitors from the pericarps of Punica granatum L.
PubMed: Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
PubMed: In vitro screening of antimotility effect on human sperm with polyphenolic compounds purified from Chinese herbal medicines.
PubMed: Tannins occurring in the toxic Brazilian plant Thiloa glaucocarpa.
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