girinimbine
 
Notes:
None found
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CAS Number: 23095-44-5Picture of molecule3D/inchi
Nikkaji Web: J16.770C
XlogP3-AA: 4.70 (est)
Molecular Weight: 263.33969000
Formula: C18 H17 N O
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.03098 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for girinimbine usage levels up to:
 not for fragrance use.
 
Recommendation for girinimbine flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 96943
National Institute of Allergy and Infectious Diseases: Data
 3,3,5-trimethyl-11H-pyrano[3,2-a]carbazole
Chemidplus: 0023095445
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References:
 3,3,5-trimethyl-11H-pyrano[3,2-a]carbazole
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 96943
Pubchem (cas): 23095-44-5
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB30241
FooDB: FDB002064
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 murraya koenigii root
Search Trop  Picture
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Synonyms:
 pyrano(3,2-a)carbazole, 3,11-dihydro-3,3,5-trimethyl-
3,3,5-trimethyl-11H-pyrano[3,2-a]carbazole
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Articles:
PubMed: Anticancer and anti-inflammatory activities of girinimbine isolated fromMurraya koenigii.
PubMed: Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities.
PubMed: In vitro and in vivo anti-angiogenic activity of girinimbine isolated from Murraya koenigii.
PubMed: Efficient construction of pyrano[3,2-a]carbazoles: application to a biomimetic total synthesis of cyclized monoterpenoid pyrano[3,2-a]carbazole alkaloids.
PubMed: Apoptosis Effect of Girinimbine Isolated from Murraya koenigii on Lung Cancer Cells In Vitro.
PubMed: Chemical constituents from stem bark and roots of Clausena anisata.
PubMed: Anti-tumour promoting activity and antioxidant properties of girinimbine isolated from the stem bark of Murraya koenigii S.
PubMed: A new carbazole alkaloid from the leaves of Malayan Murraya koenigii.
PubMed: The growth suppressing effects of girinimbine on HepG2 involve induction of apoptosis and cell cycle arrest.
PubMed: Efficient iron-mediated approach to pyrano[3,2-a]carbazole alkaloids--first total syntheses of O-methylmurrayamine A and 7-methoxymurrayacine, first asymmetric synthesis and assignment of the absolute configuration of (-)-trans-dihydroxygirinimbine.
PubMed: Murrayakoeninol--a new carbazole alkaloid from Murraya koenigii (Linn) Spreng.
PubMed: Anti-trichomonal, biochemical and toxicological activities of methanolic extract and some carbazole alkaloids isolated from the leaves of Murraya koenigii growing in Nigeria.
PubMed: [Study on carbazole alkaloids of Murraya microphylla].
PubMed: Carbazole alkaloids as new cell cycle inhibitor and apoptosis inducers from Clausena dunniana Levl.
PubMed: Inhibition of cyclooxygenase activity and increase in platelet cyclic AMP by girinimbine, isolated from Murraya euchrestifolia.
PubMed: Antimicrobial activity of carbazole derivatives.
PubMed: Synthesis of girinimbine and (plus or minus) mahanimbine.
PubMed: On the structures of girinimbine, mahanimbine, isomahanimbine, koenimbidine and murrayacine.
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