heptaphylline
3-formyl-2-hydroxy-1-prenylcarbazole
 
Notes:
None found
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CAS Number: 17750-35-5Picture of molecule3D/inchi
Nikkaji Web: J13.606I
XlogP3-AA: 5.00 (est)
Molecular Weight: 279.33889000
Formula: C18 H17 N O2
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.03683 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for heptaphylline usage levels up to:
 not for fragrance use.
 
Recommendation for heptaphylline flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5318015
National Institute of Allergy and Infectious Diseases: Data
 2-hydroxy-1-(3-methylbut-2-enyl)-9H-carbazole-3-carbaldehyde
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References:
 2-hydroxy-1-(3-methylbut-2-enyl)-9H-carbazole-3-carbaldehyde
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 5318015
Pubchem (cas): 17750-35-5
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB30219
FooDB: FDB002038
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 clausena lansium leaf
Search Trop  Picture
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Synonyms:
3-formyl-2-hydroxy-1-prenyl carbazole
3-formyl-2-hydroxy-1-prenylcarbazole
2-hydroxy-1-(3-methylbut-2-enyl)-9H-carbazole-3-carbaldehyde
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Articles:
PubMed: A new coruleoellagic acid derivative from stems of Rhodamnia dumetorum.
PubMed: Carbazole-pyranocoumarin conjugate and two carbazole alkaloids from the stems of Clausena excavata.
PubMed: Synthesis of Carbazole Alkaloids by Ring-Closing Metathesis and Ring Rearrangement-Aromatization.
PubMed: Heptaphylline induces apoptosis in human colon adenocarcinoma cells through bid and Akt/NF-κB (p65) pathways.
PubMed: [Synthetic studies on natural products with aromatic nitrogen heterocycles based on development of the methods for the formation of aryl carbon-nitrogen bond].
PubMed: Synthesis of substituted indoline and carbazole by benzyne-mediated cyclization-functionalization.
PubMed: Synthesis and cytotoxic activity of the heptaphylline and 7-methoxyheptaphylline series.
PubMed: Claurailas A-D, cytotoxic carbazole alkaloids from the roots of Clausena harmandiana.
PubMed: Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.
PubMed: Coumarins and carbazoles with antiplasmodial activity from Clausena harmandiana.
PubMed: Synthesis of heptaphylline.
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