| PubMed: | Exploring the immunomodulatory and anticancer properties of zerumbone. |
| PubMed: | In Vitro Anti-Leishmanial Activity of Essential Oils Extracted from Vietnamese Plants. |
| PubMed: | Properties of macerated herbal oil. |
| PubMed: | Healing potential of zerumbone ointment on experimental full-thickness excision cutaneous wounds in rat. |
| PubMed: | Zerumbone reduced the inflammatory response of acute lung injury in endotoxin-treated mice via Akt-NFκB pathway. |
| PubMed: | Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway. |
| PubMed: | Contact and Repellant Activities of Zerumbone and Its Analogues from the Essential Oil of Zingiber zerumbet (L.) Smith against Lasioderma serricorne. |
| PubMed: | Antidermatophytic and Protease-inhibiting Activities of Zerumbone: A Natural Sesquiterpene from the Rhizome of Zingiber zerumbet (L.) Roscoe ex J.E; Smith. |
| PubMed: | Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts. |
| PubMed: | Zerumbone alleviates chronic constriction injury-induced allodynia and hyperalgesia through serotonin 5-HT receptors. |
| PubMed: | Zerumbone, a Phytochemical of Subtropical Ginger, Protects against Hyperglycemia-Induced Retinal Damage in Experimental Diabetic Rats. |
| PubMed: | Corrigendum to "Zingiber zerumbet (L.) Smith: A Review of Its Ethnomedicinal, Chemical, and Pharmacological Uses". |
| PubMed: | Locomotor-Reducing Activity of Sesquiterpenes Related to Zingiber zerumbet Essential Oil and Hexahydrozerumbone Derivatives. |
| PubMed: | Zerumbone, a Sesquiterpene, Controls Proliferation and Induces Cell Cycle Arrest in Human Laryngeal Carcinoma Cell Line Hep-2. |
| PubMed: | Variation in secondary metabolite production as well as antioxidant and antibacterial activities of Zingiber zerumbet (L.) at different stages of growth. |
| PubMed: | Antinociceptive and Anti-Inflammatory Effects of Zerumbone against Mono-Iodoacetate-Induced Arthritis. |
| PubMed: | Molecular phylogenetics and anti-Pythium activity of endophytes from rhizomes of wild ginger congener, Zingiber zerumbet Smith. |
| PubMed: | Induction of apoptosis by zerumbone isolated from Zingiber zerumbet (L.) Smith in protozoan parasite Leishmania donovani due to oxidative stress. |
| PubMed: | Heterologous Expression, Purification, and Biochemical Characterization of α-Humulene Synthase from Zingiber zerumbet Smith. |
| PubMed: | Consumption of Polyphenol-Rich Zingiber Zerumbet Rhizome Extracts Protects against the Breakdown of the Blood-Retinal Barrier and Retinal Inflammation Induced by Diabetes. |
| PubMed: | Engineering Methylobacterium extorquens for de novo synthesis of the sesquiterpenoid α-humulene from methanol. |
| PubMed: | The ethanol extract of Zingiber zerumbet rhizomes mitigates vascular lesions in the diabetic retina. |
| PubMed: | Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult. |
| PubMed: | Antiallodynic and antihyperalgesic effects of zerumbone on a mouse model of chronic constriction injury-induced neuropathic pain. |
| PubMed: | Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis. |
| PubMed: | Gastroprotective potential against indomethacin and safety assessment of the homology of medicine and food formula cuttlebone complex. |
| PubMed: | Development of an Efficient Virus Induced Gene Silencing Strategy in the Non-Model Wild Ginger-Zingiber zerumbet and Investigation of Associated Proteome Changes. |
| PubMed: | Antisecretory, gastroprotective, antioxidant and anti-Helicobcter pylori activity of zerumbone from Zingiber zerumbet (L.) Smith. |
| PubMed: | Zerumbone protects INS-1 rat pancreatic beta cells from high glucose-induced apoptosis through generation of reactive oxygen species. |
| PubMed: | Effects of Selected Physicochemical Parameters on Zerumbone Production of Zingiber zerumbet Smith Cell Suspension Culture. |
| PubMed: | [Mechanisms underlying physiological functions of food factors via non-specific interactions with biological proteins]. |
| PubMed: | In vitro vasoactivity of zerumbone from Zingiber zerumbet. |
| PubMed: | Binding mode analysis of zerumbone to key signal proteins in the tumor necrosis factor pathway. |
| PubMed: | Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice. |
| PubMed: | Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation. |
| PubMed: | Zerumbone inhibits growth of hormone refractory prostate cancer cells by inhibiting JAK2/STAT3 pathway and increases paclitaxel sensitivity. |
| PubMed: | Studies on α-glucosidase, aldose reductase and glycation inhibitory properties of sesquiterpenes and flavonoids of Zingiber zerumbet Smith. |
| PubMed: | Locomotor-reducing effects and structural characteristics of inhaled zerumbone and tetrahydrozerumbone derivatives. |
| PubMed: | Repellency of essential oils extracted from Thai native plants against Aedes aegypti (Linn.) and Culex quinquefasciatus (Say). |
| PubMed: | A new species of Chaeridiona Baly (Coleoptera: Chrysomelidae: Cassidinae: Oncocephalini) infesting ginger Zingiber officinale Roscoe) and turmeric (Curcuma longa L.) in India and redescription of Chaeridiona pseudometallica Basu. |
| PubMed: | Lipid-lowering effects of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, in high-fat diet-induced hyperlipidemic hamsters. |
| PubMed: | Effect of Zingiber zerumbet essential oils and zerumbone inhalation on body weight of Sprague Dawley rat. |
| PubMed: | Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced inflammatory response. |
| PubMed: | Metabolic profiling of Zingiber zerumbet following Pythium myriotylum infection: investigations on the defensive role of the principal secondary metabolite, zerumbone. |
| PubMed: | Zerumbone from Ginger (Monoterpenoid). |
| PubMed: | The ethanol extract of Zingiber zerumbet Smith attenuates non-alcoholic fatty liver disease in hamsters fed on high-fat diet. |
| PubMed: | Zerumbone, a Natural Cyclic Sesquiterpene of Zingiber zerumbet Smith, Attenuates Nonalcoholic Fatty Liver Disease in Hamsters Fed on High-Fat Diet. |
| PubMed: | Zerumbone inhibits tumor angiogenesis via NF-κB in gastric cancer. |
| PubMed: | Evaluation of larvicidal activity and brine shrimp toxicity of rhizome extracts of Zingiber zerumbet (L.) Smith. |
| PubMed: | Antibacterial and antimutagenic activities of novel zerumbone analogues. |
| PubMed: | Inclusion Complex of Zerumbone with Hydroxypropyl- β -Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio. |
| PubMed: | Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis. |
| PubMed: | The Ethanol Extract of Zingiber zerumbet Attenuates Streptozotocin-Induced Diabetic Nephropathy in Rats. |
| PubMed: | 6-gingerol prevents adipogenesis and the accumulation of cytoplasmic lipid droplets in 3T3-L1 cells. |
| PubMed: | Suites of terpene synthases explain differential terpenoid production in ginger and turmeric tissues. |
| PubMed: | Molecular characterization of ZzR1 resistance gene from Zingiber zerumbet with potential for imparting Pythium aphanidermatum resistance in ginger. |
| PubMed: | Zerumbone, an electrophilic sesquiterpene, induces cellular proteo-stress leading to activation of ubiquitin-proteasome system and autophagy. |
| PubMed: | DNA fragmentation is not associated with apoptosis in zerumbone-induced HepG2 cells. |
| PubMed: | Chemical composition of the essential oil of Zingiber zerumbet var. darcyi. |
| PubMed: | Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells. |
| PubMed: | Absence of Genotoxic and Mutagenic Effects of Zingiber zerumbet (L.) Smith (Zingiberaceae) Extract. |
| PubMed: | Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer. |
| PubMed: | Regulation of lipid disorders by ethanol extracts from Zingiber zerumbet in high-fat diet-induced rats. |
| PubMed: | Acute and 28-Day Subchronic Oral Toxicity of an Ethanol Extract of Zingiber zerumbet (L.) Smith in Rodents. |
| PubMed: | Dietary supplementation of Zingiber officinale and Zingiber zerumbet to heat-stressed broiler chickens and its effect on heat shock protein 70 expression, blood parameters and body temperature. |
| PubMed: | Zerumbone, a Southeast Asian Ginger Sesquiterpene, Induced Apoptosis of Pancreatic Carcinoma Cells through p53 Signaling Pathway. |
| PubMed: | Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats. |
| PubMed: | Cytotoxicity of the rhizome of medicinal plants. |
| PubMed: | Beneficial impact of Zingiber zerumbet on insulin sensitivity in fructose-fed rats. |
| PubMed: | Antimicrobial activities of the rhizome extract of Zingiber zerumbet Linn. |
| PubMed: | Contact toxicity, feeding reduction, and repellency of essential oils from three plants from the ginger family (Zingiberaceae) and their major components against Sitophilus zeamais and Tribolium castaneum. |
| PubMed: | An in vitro evaluation of the anthelmintic activity of Hedychium spichatum rhizomes and Zingiber zerumbet rhizomes on the Pheritima Posthuma model: A comparative study. |
| PubMed: | An in vitro evaluation of anthelmintic activity of Zingiber zerumbet rhizomes and Cucurbita maxima seeds on Pheretima posthuma model: A comparative study. |
| PubMed: | A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet. |
| PubMed: | Antinociceptive effect of the essential oil of Zingiber zerumbet in mice: possible mechanisms. |
| PubMed: | Zingiber zerumbet (L.) Smith: A Review of Its Ethnomedicinal, Chemical, and Pharmacological Uses. |
| PubMed: | Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance. |
| PubMed: | Attractive reactivity of a natural product, zerumbone. |
| PubMed: | Efficient functional analysis system for cyanobacterial or plant cytochromes P450 involved in sesquiterpene biosynthesis. |
| PubMed: | Preliminary analysis of the anti-inflammatory activity of essential oils of Zingiber zerumbet. |
| PubMed: | Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. |
| PubMed: | Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells. |
| PubMed: | Insecticidal and larvicidal activities of medicinal plant extracts against mosquitoes. |
| PubMed: | Chemical composition and larvicidal activity of edible plant-derived essential oils against the pyrethroid-susceptible and -resistant strains of Aedes aegypti (Diptera: Culicidae). |
| PubMed: | Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice. |
| PubMed: | Antiinflammatory and antinociceptive activities of Zingiber zerumbet methanol extract in experimental model systems. |
| PubMed: | Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet). |
| PubMed: | Evaluation of the genotoxicity of zerumbone in cultured human peripheral blood lymphocytes. |
| PubMed: | Immunomodulatory effects of zerumbone isolated from roots of Zingiber zerumbet. |
| PubMed: | In vitro covalent binding proteins of zerumbone, a chemopreventive food factor. |
| PubMed: | Antinociceptive activity of the essential oil of Zingiber zerumbet. |
| PubMed: | Preliminary analysis of the antinociceptive activity of zerumbone. |
| PubMed: | In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa). |
| PubMed: | Suppression of lipopolysaccharide-stimulated inducible nitric oxide synthase (iNOS) expression by a novel humulene derivative in macrophage cells. |
| PubMed: | Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice. |
| PubMed: | Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells. |
| PubMed: | Histone deacetylase inhibitors from the rhizomes of Zingiber zerumbet. |
| PubMed: | Defence transcriptome profiling of Zingiber zerumbet (L.) Smith by mRNA differential display. |
| PubMed: | Molecular cloning and functional characterization of alpha-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet Smith). |
| PubMed: | Isolation and functional characterization of a beta-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. |
| PubMed: | Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation. |
| PubMed: | Development of SCAR (sequence-characterized amplified region) markers as a complementary tool for identification of ginger (Zingiber officinale Roscoe) from crude drugs and multicomponent formulations. |
| PubMed: | Zerumbone suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells. |
| PubMed: | Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio. |
| PubMed: | Modulation of P-glycoprotein-mediated resistance by kaempferol derivatives isolated from Zingiber zerumbet. |
| PubMed: | Anti-allergic activity of some selected plants in the Zingiberaceae family. |
| PubMed: | The anti-amoebic activity of some medicinal plants used by AIDS patients in southern Thailand. |
| PubMed: | Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion. |
| PubMed: | Humulene derivatives from Zingiber zerumbet with the inhibitory effects on lipopolysaccharide-induced nitric oxide production. |
| PubMed: | Potentially bioactive two new natural sesquiterpenoids from the rhizomes of Zingiber zerumbet. |
| PubMed: | Antitumor effects of zerumbone from Zingiber zerumbet in P-388D1 cells in vitro and in vivo. |
| PubMed: | The in vitro anti-giardial activity of extracts from plants that are used for self-medication by AIDS patients in southern Thailand. |
| PubMed: | Screening for antihyperglycaemic activity in several local herbs of Malaysia. |
| PubMed: | Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. |
| PubMed: | Flavonoids and aromatic compounds from the rhizomes of Zingiber zerumbet. |
| PubMed: | Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination. |
| PubMed: | Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite. |
| PubMed: | Chemistry of zerumbone. 2. Regulation of ring bond cleavage and unique antibacterial activities of zerumbone derivatives. |
| PubMed: | Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet. |
| PubMed: | Chemistry of Zerumbone. 1. Simplified Isolation, Conjugate Addition Reactions, and a Unique Ring Contracting Transannular Reaction of Its Dibromide. |
| PubMed: | Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation. |