trichosanthes kirilowii root extract
extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae
 
Notes:
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Category: cosmetic ingredient for skin protecting
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin protecting agents
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Suppliers:
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
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GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin protecting
Recommendation for trichosanthes kirilowii root extract usage levels up to:
 not for fragrance use.
 
Recommendation for trichosanthes kirilowii root extract flavor usage levels up to:
 not for flavor use.
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Safety References:
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References:
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
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Potential Uses:
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Occurrence (nature, food, other): note
 trichosanthes kirilowii root
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Synonyms:
 extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae
 trichosanthes obtusiloba root extract
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Articles:
PubMed: Ribosome-inactivating Proteins from Root Tubers and Seeds of Trichosan-thes kirilowii and Other Trichosanthes Species.
PubMed: In vitro Screening and Evaluation of 37 Traditional Chinese Medicines for Their Potential to Activate Peroxisome Proliferator-Activated Receptors-γ.
PubMed: Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway.
PubMed: The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3.
PubMed: Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway.
PubMed: A lower pH value benefits regeneration of Trichosanthes kirilowii by somatic embryogenesis, involving rhizoid tubers (RTBs), a novel structure.
PubMed: BDP-30, a systemic resistance inducer from Boerhaavia diffusa L., suppresses TMV infection, and displays homology with ribosome-inactivating proteins.
PubMed: [Effect of yanghe huayan decoction on precancerosis of breast cancer, protein and mRNA expression of ki67: an experimental research].
PubMed: A novel extraction of trichosanthin from Trichosanthes kirilowii roots using three-phase partitioning and its in vitro anticancer activity.
PubMed: Isolation and characterization of a rhizobacterial antagonist of root-knot nematodes.
PubMed: Trichosanthin, a Chinese medicine for the medical treatment of ectopic pregnancy with high levels of β-hCG.
PubMed: Identification of novel pregnane X receptor activators from traditional Chinese medicines.
PubMed: Possible mechanisms of trichosanthin-induced apoptosis of tumor cells.
PubMed: Trichosanthin, an extract of Trichosanthes kirilowii, effectively prevents acute rejection of major histocompatibility complex-mismatched mouse skin allograft.
PubMed: [Tissue culture and rapid propagation of Trichosanthes kirilowii].
PubMed: Trichosanthin induced Th2 polarization status.
PubMed: [Protective effects of trichosanthin in Herpes simplex virus-1 encephalitis in mice].
PubMed: Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties.
PubMed: Effect of N- and C-terminal deletions on the RNA N-glycosidase activity and the antigenicity of karasurin-A, a ribosome-inactivating protein from Trichosanthes kirilowii var. japonica.
PubMed: [Activation of G protein on the membrane of TCS-sensitive cells].
PubMed: [Genetic transformation of hairy roots in Trichosanthes kirilowii Maxim. by Ti and Ri plasmids].
PubMed: Cucurbitacins from Trichosanthes kirilowii as the inhibitory components on tyrosinase activity and melanin synthesis of B16/F10 melanoma cells.
PubMed: Expression of recombinant trichosanthin, a ribosome-inactivating protein, in transgenic tobacco.
PubMed: The interaction of trichosanthin with supported phospholipid membranes studied by surface plasmon resonance.
PubMed: Anti-HIV-1 activity of trichobitacin, a novel ribosome-inactivating protein.
PubMed: Carbohydrate specificity of an agglutinin isolated from the root of Trichosanthes kirilowii.
PubMed: Effect of karasurin-A on nitric oxide production by murine macrophages and mitogenic response of murine splenocytes in vitro.
PubMed: Amino acid sequences and ribosome-inactivating activities of karasurin-B and karasurin-C.
PubMed: A new method for the detection and quantitative measurement of the contents of trichosanthes root component composing Chinese traditional medicines.
PubMed: A simplified procedure for the purification of trichosanthin (a type 1 ribosome inactivating protein) from Trichosanthes kirilowii root tubers.
PubMed: Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica.
PubMed: In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells.
PubMed: Biosynthesis of defense-related proteins in transformed root cultures of Trichosanthes kirilowii Maxim. var japonicum (Kitam.).
PubMed: Development and application of an enzyme immunoassay for karasurin A, an effective protein component of Trichosanthes kirilowii Max. var. japonicum Kitam.
PubMed: Minireview: trichosanthin--a protein with multiple pharmacological properties.
PubMed: The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxin.
PubMed: Presence of protein polymorphism in karasurin, an abortifacient and anti-tumor protein, identified with physicochemical properties.
PubMed: Toxicity and activity of purified trichosanthin.
PubMed: Trichosanthin-monoclonal antibody conjugate specifically cytotoxic to human hepatoma cells in vitro.
PubMed: The complete amino acid sequence of an abortifacient protein, karasurin.
PubMed: Isolation and characterization of a new abortifacient protein, karasurin, from root tubers of Trichosanthes kirilowii Max. var. japonicum Kitam.
PubMed: Cloning of trichosanthin cDNA and its expression in Escherichia coli.
PubMed: [Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"].
PubMed: [Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam].
PubMed: Beta-trichosanthin: a new abortifacient protein from the Chinese drug, wangua, Trichosanthes cucumeroides.
PubMed: Isolation and characterization of an immunosuppressive protein from Trichosanthes kirilowii root tubers.
PubMed: The immunomodulatory and antitumor activities of trichosanthin-an abortifacient protein isolated from tian-hua-fen (Trichosanthes kirilowii).
PubMed: Chemical and biological characterization of the galactose binding lectins from Trichosanthes kirilowii root tubers.
PubMed: Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii.
PubMed: Screening of Trichosanthes kirilowii, Momordica charantia and Cucurbita maxima (family Cucurbitaceae) for compounds with antilipolytic activity.
PubMed: Purification, characterization and sequence determination of a double-headed trypsin inhibitor peptide from Trichosanthes kirilowii (a Chinese medical herb).
PubMed: Studies on the mechanisms of abortion induction by Trichosanthin.
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