kefiran
disaccharide consisting of glucose and galactose
 
Notes:
Isol. from Kefir grains, the inoculating material used for conversion of milk into the Russian beverage Kefir. Kefir grains consist of yeast and bacteria, predominantly Saccharomyces delbruckii and Lactobacillus brevis. About 25% of the dry material consists of the capsular polysaccharide of Lactobacillus brevis
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CAS Number: 86753-15-3Picture of molecule3D/inchi
FDA UNII: 8L821V6V99
Nikkaji Web: J567.132I
XlogP3-AA: 1.80 (est)
Molecular Weight: 266.14164000
Formula: C11 H12 Br N3
NMR Predictor: Predict (works with chrome or firefox)
Category: cosmetic ingredient for skin conditioning
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 4452 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for kefiran usage levels up to:
 not for fragrance use.
 
Recommendation for kefiran flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 23786499
National Institute of Allergy and Infectious Diseases: Data
 2-[2-(3-bromophenyl)-1H-imidazol-5-yl]ethanamine
Chemidplus: 0086753153
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References:
 2-[2-(3-bromophenyl)-1H-imidazol-5-yl]ethanamine
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 23786499
Pubchem (sid): 103193164
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
FooDB: FDB020869
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
2-[2-(3-bromophenyl)-1H-imidazol-5-yl]ethanamine
 disaccharide consisting of glucose and galactose
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Articles:
PubMed: Bioprocess development for kefiran production by Lactobacillus kefiranofaciens in semi industrial scale bioreactor.
PubMed: Kefiran-alginate gel microspheres for oral delivery of ciprofloxacin.
PubMed: Kefir induces apoptosis and inhibits cell proliferation in human acute erythroleukemia.
PubMed: Oral administration of kefiran exerts a bifidogenic effect on BALB/c mice intestinal microbiota.
PubMed: Milk kefir: composition, microbial cultures, biological activities, and related products.
PubMed: Gelling ability of kefiran in the presence of sucrose and fructose and physicochemical characterization of the resulting cryogels.
PubMed: Characterization of the new biodegradable WPI/clay nanocomposite films based on kefiran exopolysaccharide.
PubMed: Rapid detection of Lactobacillus kefiranofaciens in kefir grain and kefir milk using newly developed real-time PCR.
PubMed: Green bionanocomposite based on kefiran and cellulose nanocrystals produced from beer industrial residues.
PubMed: Effect of γ-irradiation on the physical and mechanical properties of kefiran biopolymer film.
PubMed: Kefir: a multifaceted fermented dairy product.
PubMed: Preparation of UV-protective kefiran/nano-ZnO nanocomposites: physical and mechanical properties.
PubMed: Preparation and characterization of kefiran electrospun nanofibers.
PubMed: The improvement of characteristics of biodegradable films made from kefiran-whey protein by nanoparticle incorporation.
PubMed: Kefir fermented milk and kefiran promote growth of Bifidobacterium bifidum PRL2010 and modulate its gene expression.
PubMed: Development and characterization of the kefiran-whey protein isolate-TiO2 nanocomposite films.
PubMed: Application of culture-dependent and culture-independent methods for the identification of Lactobacillus kefiranofaciens in microbial consortia present in kefir grains.
PubMed: Film forming microbial biopolymers for commercial applications--a review.
PubMed: Cultivating conditions effects on kefiran production by the mixed culture of lactic acid bacteria imbedded within kefir grains.
PubMed: Development of a new method for determination of exopolysaccharide quantity in fermented milk products and its application in technology of kefir production.
PubMed: Development and characterisation of composite films made of kefiran and starch.
PubMed: Structural investigation and response surface optimisation for improvement of kefiran production yield from a low-cost culture medium.
PubMed: Kefiran suppresses antigen-induced mast cell activation.
PubMed: Rheological and structural characterisation of film-forming solutions and biodegradable edible film made from kefiran as affected by various plasticizer types.
PubMed: Characterization of edible emulsified films with low affinity to water based on kefiran and oleic acid.
PubMed: Oral administration of kefiran induces changes in the balance of immune cells in a murine model.
PubMed: Milk kefir: ultrastructure, antimicrobial activity and efficacy on aflatoxin B1 production by Aspergillus flavus.
PubMed: Use of whey lactose from dairy industry for economical kefiran production by Lactobacillus kefiranofaciens in mixed cultures with yeasts.
PubMed: Production of fermented cheese whey-based beverage using kefir grains as starter culture: evaluation of morphological and microbial variations.
PubMed: Kefiran reduces atherosclerosis in rabbits fed a high cholesterol diet.
PubMed: Assessment of the sequential simulated gastrointestinal tolerance of lactic acid bacteria from kefir grains by response surface methodology.
PubMed: Kefiran protects Caco-2 cells from cytopathic effects induced by Bacillus cereus infection.
PubMed: Inhibitory effect of kefiran on ovalbumin-induced lung inflammation in a murine model of asthma.
PubMed: Kefiran antagonizes cytopathic effects of Bacillus cereus extracellular factors.
PubMed: Fed-batch coculture of Lactobacillus kefiranofaciens with Saccharomyces cerevisiae for effective production of kefiran.
PubMed: Effects of the oral administration of the exopolysaccharide produced by Lactobacillus kefiranofaciens on the gut mucosal immunity.
PubMed: Kefir: a symbiotic yeasts-bacteria community with alleged healthy capabilities.
PubMed: Anti-inflammatory properties of kefir and its polysaccharide extract.
PubMed: Interactions between Lactobacillus kefiranofaciens and Saccharomyces cerevisiae in mixed culture for kefiran production.
PubMed: Antimicrobial and healing activity of kefir and kefiran extract.
PubMed: Effects of an exopolysaccharide (kefiran) on lipids, blood pressure, blood glucose, and constipation.
PubMed: Clarification of interactions among microorganisms and development of co-culture system for production of useful substances.
PubMed: Structural characterization and biological activities of an exopolysaccharide kefiran produced by Lactobacillus kefiranofaciens WT-2B(T).
PubMed: The antimicrobial properties of different strains of Lactobacillus spp. isolated from kefir.
PubMed: Exopolysaccharides produced by lactic acid bacteria of kefir grains.
PubMed: Enhanced kefiran production by mixed culture of Lactobacillus kefiranofaciens and Saccharomyces cerevisiae.
PubMed: Modelling and optimization of environmental conditions for kefiran production by Lactobacillus kefiranofaciens.
PubMed: Isolation and characterisation of a ropy Lactobacillus strain producing the exopolysaccharide kefiran.
PubMed: Enhancing effects of food components on the production of interferon β from animal cells suppressed by stress hormones.
PubMed: Some taxonomical characteristics of encapsulated Lactobacillus sp. KPB-167B isolated from kefir grains and characterization of its extracellular polysaccharide.
PubMed: Immunofluorescence microscopic studies on distribution of Lactobacillus kefiranofaciens and Lactobacillus kefir in kefir grains.
PubMed: Kefiran, a novel polysaccharide produced in the kefir grain by Lactobacillus brevis.
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