kallikrein
kallidinogenase
 
Notes:
None found
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CAS Number: 9001-01-8 
ECHA EC Number: 232-574-5
MDL: MFCD00131428
Category: cosmetic ingredient for skin and hair conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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US Patents: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: hair conditioning
skin conditioning
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Suppliers:
Sigma-Aldrich: Sigma
For experimental / research use only.
Kallikrein from human plasma buffered aqueous solution, ≥5 units/mg protein
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin and hair conditioning
Recommendation for kallikrein usage levels up to:
 not for fragrance use.
 
Recommendation for kallikrein flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
Cancer Citations: Search
Toxicology Citations: Search
EPA GENetic TOXicology: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0009001018
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References:
Pubchem (sid): 135272645
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Other Information:
HMDB (The Human Metabolome Database): Search
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 bradykini
 callicrein
 kallidinogenase
 kininogenin
 onokrein P
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Articles:
PubMed: The beneficial effects of taurine in preventing metabolic syndrome.
PubMed: Oral medicine case book 64: Some aspects of the pathophysiology of angioedema with special reference to the upper aerodigestive tract.
PubMed: Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice.
PubMed: Lower Levels of Human MOB3B Are Associated with Prostate Cancer Susceptibility and Aggressive Clinicopathological Characteristics.
PubMed: Management of acute attacks of hereditary angioedema: role of ecallantide.
PubMed: Early childhood caries is associated with genetic variants in enamel formation and immune response genes.
PubMed: The association of genetic variations with sensitivity of blood pressure to dietary salt: A narrative literature review.
PubMed: Risk factors for the development of essential hypertension in a Mongolian population of China: a case-control study.
PubMed: Measurement of aberrant glycosylation of prostate specific antigen can improve specificity in early detection of prostate cancer.
PubMed: Safety, tolerability and anti-tumour activity of the androgen biosynthesis inhibitor ASP9521 in patients with metastatic castration-resistant prostate cancer: multi-centre phase I/II study.
PubMed: A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer--the U.K. NCRN Pomi-T study.
PubMed: Opposing roles of folate in prostate cancer.
PubMed: Magnetic bead-based reverse colorimetric immunoassay strategy for sensing biomolecules.
PubMed: HAE update: determining optimal patient specific therapy.
PubMed: Progress in the emergency management of hereditary angioedema: focus on new treatment options in the United States.
PubMed: Characterization of currently marketed heparin products: adverse event relevant bioassays.
PubMed: Complement C1 esterase inhibitor levels linked to infections and contaminated heparin-associated adverse events.
PubMed: Ecallantide for treatment of acute attacks of hereditary angioedema.
PubMed: IgE antibodies to animal-derived lipocalin, kallikrein and secretoglobin are markers of bronchial inflammation in severe childhood asthma.
PubMed: Isolation and characterisation of a kallikrein-like enzyme from Agkistrodon halys pallas snake venom.
PubMed: Salivary 8-OHdG Induction by Physical Exercise Training Under Food Restriction.
PubMed: Subcutaneous infusion of human C1 inhibitor in swine.
PubMed: Biomarkers of in vivo fertility in sperm and seminal plasma of fertile stallions.
PubMed: Hereditary angioedema: current and emerging treatment options.
PubMed: FDA approves kallikrein inhibitor to treat hereditary angioedema.
PubMed: Availability of saliva for the assessment of alterations in the autonomic nervous system caused by physical exercise training.
PubMed: [Effects of human urinary tissue kallikreins on vasodilation of basilar artery in rabbits with symptomatic cerebral vasospasm].
PubMed: [Phenotype analysis and the molecular mechanism of enamel hypoplasia].
PubMed: Isolation of human renin inhibitor from soybean: soyasaponin I is the novel human renin inhibitor in soybean.
PubMed: Contaminated heparin associated with adverse clinical events and activation of the contact system.
PubMed: Prostate-specific Antigen: Its Usefulness in Clinical Medicine.
PubMed: Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2007.
PubMed: Hereditary angiodema: a current state-of-the-art review, VI: novel therapies for hereditary angioedema.
PubMed: Effect of angiotensin converting enzyme inhibitor enalapril on body weight and composition in young rats.
PubMed: Purification and characterization of a fibrinolytic enzyme of Bacillus subtilis DC33, isolated from Chinese traditional Douchi.
PubMed: New strategies for the medical treatment of prostate cancer.
PubMed: Review and application of serine protease inhibition in coronary artery bypass graft surgery.
PubMed: Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats.
PubMed: [Mineralization of dental hard tissues].
PubMed: Renal and hormonal effects of water deprivation in late-term pregnant rats.
PubMed: Effects of ethanol administration at a high-dose level on the stimulatory action by bradykinin in vascular permeability.
PubMed: Detection of serine proteases in extracts of the domestic mite Blomia tropicalis.
PubMed: An improved, reliable and practical kinetic assay for the detection of prekallikrein activator in blood products.
PubMed: Estrogen and tamoxifen interplay with T(3) in male rats: pharmacologically distinct classes of estrogen responses affecting growth, bone, and lipid metabolism, and their relation to serum GH and IGF-I.
PubMed: The link between high-fat meals and postprandial activation of blood coagulation factor VII possibly involves kallikrein.
PubMed: Inhibition of Df-protease associated with allergic diseases by polyphenol.
PubMed: Bradykinin release from high molecular weight kininogen and increase in plasma kallikrein-like activity following sensory stimulation by food in the rat.
PubMed: Fumaric acid, anti-thrombin substance from Rhizopus javanicus.
PubMed: Effect of high salt intake in mutant mice lacking bradykinin-B2 receptors.
PubMed: rK7-kallikrein in rat kidney and urine.
PubMed: Low-level lead exposure and blood pressure.
PubMed: Environmental determinants of urinary kallikrein excretion.
PubMed: Plasma kallikrein clearance by the liver in food-restricted rats.
PubMed: [Effects of dietary K on blood pressure, prostaglandin, and kallikrein in renovascular hypertensive rats].
PubMed: [Effect of food loading on the activity of the kallikrein-kinin system of the blood in an experiment].
PubMed: [Decrease in urinary excretion of active kallikrein in conscious young and adult spontaneously hypertensive rats].
PubMed: [Urinary kallikrein activity in conscious spontaneously-hypertensive rats: development as a function of age].
PubMed: [Kallikrein-kinin, fibrinolytic and coagulation systems of the blood of patients with salmonellosis treated with indomethacin].
PubMed: [The effect of dopaminergic stimulation and inhibition on the urinary excretion of aldosterone and kallikrein in spontaneously hypertensive rats].
PubMed: The danger of "yellow dyes" (tartrazine) to allergic subjects.
PubMed: Changes in serotonin metabolism during migraine attacks.
PubMed: URTICARIA: A REVIEW OF LABORATORY AND CLINICAL OBSERVATIONS.
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