ilomastat, 142880-36-2

Articles:

PubMed:	Association of MMP-8 with obesity, smoking and insulin resistance.
PubMed:	Selective non-zinc binding MMP-2 inhibitors: Novel benzamide Ilomastat analogs with anti-tumor metastasis.
PubMed:	ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4.
PubMed:	Bisphenol A and Related Alkylphenols Exert Nongenomic Estrogenic Actions Through a G Protein-Coupled Estrogen Receptor 1 (Gper)/Epidermal Growth Factor Receptor (Egfr) Pathway to Inhibit Meiotic Maturation of Zebrafish Oocytes.
PubMed:	Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model.
PubMed:	Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2).
PubMed:	Involvement of epidermal growth factor receptors and mitogen-activated protein kinase in progestin-induction of sperm hypermotility in Atlantic croaker through membrane progestin receptor-alpha.
PubMed:	Reducing tumor growth and angiogenesis using a triple therapy measured with Contrast-enhanced ultrasound (CEUS).
PubMed:	Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts.
PubMed:	Near-infrared triple-helical peptide with quenched fluorophores for optical imaging of MMP-2 and MMP-9 proteolytic activity in vivo.
PubMed:	Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells.
PubMed:	Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma.
PubMed:	Moderate inhibition of myocardial matrix metalloproteinase-2 by ilomastat is cardioprotective.
PubMed:	Molecular dynamic simulations of ocular tablet dissolution.
PubMed:	Proteolysis controls endogenous substance P levels.
PubMed:	Matrix metalloproteinase inhibition protects CyPD knockout mice independently of RISK/mPTP signalling: a parallel pathway to protection.
PubMed:	Initial characterization of a dually radiolabeled peptide for simultaneous monitoring of protein targets and enzymatic activity.
PubMed:	Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates.
PubMed:	Characterisation of ilomastat for prolonged ocular drug release.
PubMed:	Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells.
PubMed:	Preparation and in vitro evaluation of an ilomastat microemulsion gel by a self-microemulsifying system.
PubMed:	Novel Gd(III)-based probes for MR molecular imaging of matrix metalloproteinases.
PubMed:	Matrix metalloproteinase inhibitor attenuates cochlear lateral wall damage induced by intratympanic instillation of endotoxin.
PubMed:	Effects of platelet-rich and -poor plasma on the reparative response of gingival fibroblasts.
PubMed:	Involvement of epidermal growth factor receptor signaling in estrogen inhibition of oocyte maturation mediated through the G protein-coupled estrogen receptor (Gper) in zebrafish (Danio rerio).
PubMed:	LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells.
PubMed:	Relative roles of doxycycline and cation chelation in endothelial glycan shedding and adhesion of leukocytes.
PubMed:	Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity.
PubMed:	Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases.
PubMed:	Role of iNOS and peroxynitrite-matrix metalloproteinase-2 signaling in myocardial late preconditioning in rats.
PubMed:	Matrix metalloproteinase inhibition enhances the rate of nerve regeneration in vivo by promoting dedifferentiation and mitosis of supporting schwann cells.
PubMed:	Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation.
PubMed:	Anti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats.
PubMed:	Inhibition of glycan shedding and leukocyte-endothelial adhesion in postcapillary venules by suppression of matrixmetalloprotease activity with doxycycline.
PubMed:	The role of an MMP inhibitor in the regulation of mechanical tension by Dupuytren's disease fibroblasts.
PubMed:	Matrix metalloprotease expressions in both reperfusion lung injury and oleic acid lung injury models and the protective effects of ilomastat.
PubMed:	Use of a three-dimensional cell culture model to study airway smooth muscle-mast cell interactions in airway remodeling.
PubMed:	Fibrillar collagen clamps lung mesenchymal cells in a nonproliferative and noncontractile phenotype.
PubMed:	Matrix metalloproteinase inhibition reduces contraction by dupuytren fibroblasts.
PubMed:	Matrix metalloproteinase inhibitors reduce collagen gel contraction and alpha-smooth muscle actin expression by periodontal ligament cells.
PubMed:	Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury.
PubMed:	Protective effect of ilomastat on trinitrobenzenesulfonic acid-induced ulcerative colitis in rats.
PubMed:	Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor.
PubMed:	Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.
PubMed:	The effect of stress-deprivation and cyclic loading on the TIMP/MMP ratio in tendon cells: an in vitro experimental study.
PubMed:	CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.
PubMed:	Dense collagen matrix accelerates osteogenic differentiation and rescues the apoptotic response to MMP inhibition.
PubMed:	Identification of MMP-12 inhibitors by using biosensor-based screening of a fragment library.
PubMed:	Bone sialoprotein binding to matrix metalloproteinase-2 alters enzyme inhibition kinetics.
PubMed:	C-FLIP promotes the motility of cancer cells by activating FAK and ERK, and increasing MMP-9 expression.
PubMed:	Human laminin-332 degradation by Candida proteinases.
PubMed:	Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.
PubMed:	A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis).
PubMed:	Matrix metalloproteinase inhibitors prevent a decrease in the mechanical properties of stress-deprived tendons: an in vitro experimental study.
PubMed:	MT1-MMP down-regulates the glucose 6-phosphate transporter expression in marrow stromal cells: a molecular link between pro-MMP-2 activation, chemotaxis, and cell survival.
PubMed:	Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.
PubMed:	The role of matrix metalloproteinases in infant traumatic brain injury.
PubMed:	An inhaled matrix metalloprotease inhibitor prevents cigarette smoke-induced emphysema in the mouse.
PubMed:	Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-derived stromal cells.
PubMed:	Cell-cell contact activation of fibroblasts increases the expression of matrix metalloproteinases.
PubMed:	Oxygen radicals and matrix metalloproteinases mediate reperfusion liver injury.
PubMed:	Metalloproteinase inhibitors, nonantimicrobial chemically modified tetracyclines, and ilomastat block Bacillus anthracis lethal factor activity in viable cells.
PubMed:	Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition.
PubMed:	In vitro evaluation of the angiostatic potential of drugs using an endothelialized tissue-engineered connective tissue.
PubMed:	Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery.
PubMed:	Cardiac morphogenesis: matrix metalloproteinase coordination of cellular mechanisms underlying heart tube formation and directionality of looping.
PubMed:	Inflammatory proteases in chronic otitis externa.
PubMed:	Poly(ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death.
PubMed:	Evidence for disulfide involvement in the regulation of intramolecular autolytic processing by human adamalysin19/ADAM19.
PubMed:	Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity.
PubMed:	Activity-based probes for the proteomic profiling of metalloproteases.
PubMed:	MMP inhibition prevents human lens epithelial cell migration and contraction of the lens capsule.
PubMed:	A novel strategy for designing specific gelatinase A inhibitors: potential use to control tumor progression.
PubMed:	Hyaluronan cell surface binding is induced by type I collagen and regulated by caveolae in glioma cells.
PubMed:	MMPs inhibitors: new succinylhydroxamates with selective inhibition of MMP-2 over MMP-3.
PubMed:	Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells.
PubMed:	Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla.
PubMed:	Enhancement by neutrophils of collagen degradation by corneal fibroblasts.
PubMed:	Effects of matrix metalloproteinase inhibitors on bone resorption and orthodontic tooth movement.
PubMed:	Alpha 1-antitrypsin and ilomastat inhibit inflammatory proteases present in human middle ear effusions.
PubMed:	Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells.
PubMed:	Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro.
PubMed:	Matrix metalloproteinase inhibition modulates postoperative scarring after experimental glaucoma filtration surgery.
PubMed:	Human corneal epithelial cells require MMP-1 for HGF-mediated migration on collagen I.
PubMed:	Metalloproteinase shedding of Fas ligand regulates beta-amyloid neurotoxicity.
PubMed:	Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration.
PubMed:	The electrical resistance breakdown assay determines the role of proteinases in tumor cell invasion.
PubMed:	Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype.
PubMed:	Involvement of matrix metalloproteinases in the adipose conversion of 3T3-L1 preadipocytes.
PubMed:	Topical synthetic inhibitor of matrix metalloproteinases delays epidermal regeneration of human wounds.
PubMed:	Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.
PubMed:	Matrix metalloproteinases and their inhibitors regulate in vitro ureteric bud branching morphogenesis.
PubMed:	Determination of matrix metalloproteinase activity using biotinylated gelatin.
PubMed:	Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros.