ginsenosides
saponin fraction isolated from the roots of panax ginseng
 
Notes:
None found
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Category: cosmetic ingredient for skin conditioning
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
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Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for ginsenosides usage levels up to:
 not for fragrance use.
 
Recommendation for ginsenosides flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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References:
None found
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Other Information:
VCF-Online: VCF Volatile Compounds in Food
Wikipedia: View
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Potential Blenders and core components note
 
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Potential Uses:
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 panax ginseng root saponin
 saponin fraction isolated from the roots of panax ginseng
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Articles:
PubMed: BACE1 molecular docking and anti-Alzheimer's disease activities of ginsenosides.
PubMed: Ultrasonication processed Panax ginseng berry extract induces apoptosis through an intrinsic apoptosis pathway in HepG2 cells.
PubMed: Finding and Producing Probiotic Glycosylases for the Biocatalysis of Ginsenosides: A Mini Review.
PubMed: Production of ginsenoside F1 using commercial enzyme Cellulase KN.
PubMed: Enzymatic formation of compound-K from ginsenoside Rb1 by enzyme preparation from cultured mycelia of Armillaria mellea.
PubMed: Enhancing Biosynthesis of a Ginsenoside Precursor by Self-Assembly of Two Key Enzymes in Pichia pastoris.
PubMed: In Vitro and In Vivo Antioxidant Activity of Aged Ginseng (Panax ginseng).
PubMed: Whole-cell biocatalysis for producing ginsenoside Rd from Rb1 using Lactobacillus rhamnosus GG.
PubMed: Oral subchronic toxicity evaluation of a novel antitumor agent 25-methoxydammarane-3, 12, 20-triol from Panax notoginseng in Sprague-Dawley rats.
PubMed: MALDI imaging for the localization of saponins in root tissues and rapid differentiation of three Panax herbs.
PubMed: Suppression of Hepatic Cyp1a2 by Total Ginsenosides in Lipopolysaccharide-Treated Mice and Primary Mouse Hepatocytes.
PubMed: Rg3-enriched ginseng extract ameliorates scopolamine-induced learning deficits in mice.
PubMed: Accumulation characteristics and correlation analysis of five ginsenosides with different cultivation ages from different regions.
PubMed: Development of interspecies hybrids to increase ginseng biomass and ginsenoside yield.
PubMed: Black Ginseng Extract Counteracts Streptozotocin-Induced Diabetes in Mice.
PubMed: Esterification of Ginsenoside Rh2 Enhanced Its Cellular Uptake and Antitumor Activity in Human HepG2 Cells.
PubMed: Effects of ascorbic acid on α-l-arabinofuranosidase and α-l-arabinopyranosidase activities from Bifidobacterium longum RD47 and its application to whole cell bioconversion of ginsenoside.
PubMed: Production of Ginsenoside F2 by Using Lactococcus lactis with Enhanced Expression of β-Glucosidase Gene from Paenibacillus mucilaginosus.
PubMed: Enzymatic Formation of Novel Ginsenoside Rg1-α-Glucosides by Rat Intestinal Homogenates.
PubMed: Production of dammarane-type sapogenins in rice by expressing the dammarenediol-II synthase gene from Panax ginseng C.A. Mey.
PubMed: Structural Characterization of Ginsenosides from Flower Buds of Panax ginseng by RRLC-Q-TOF MS.
PubMed: Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells.
PubMed: Effects of Fusarium solani and F. oxysporum Infection on the Metabolism of Ginsenosides in American Ginseng Roots.
PubMed: Protective Effects of Processed Ginseng and Its Active Ginsenosides on Cisplatin-Induced Nephrotoxicity: In Vitro and in Vivo Studies.
PubMed: A prebiotic fiber increases the formation and subsequent absorption of compound K following oral administration of ginseng in rats.
PubMed: Production of oleanane-type sapogenin in transgenic rice via expression of β-amyrin synthase gene from Panax japonicus C. A. Mey.
PubMed: A Bacterial Metabolite, Compound K, Induces Programmed Necrosis in MCF-7 Cells via GSK3β.
PubMed: [Uncertainty evaluation for determining ginsenosides in ginseng food by HPLC].
PubMed: Efficacy and Safety of Enzyme-Modified Panax ginseng for Anti-Wrinkle Therapy in Healthy Skin: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Study.
PubMed: Anti-inflammatory potential of saponins derived from cultured wild ginseng roots in lipopolysaccharide-stimulated RAW 264.7 macrophages.
PubMed: Anti-inflammatory mechanism of ginseng saponin metabolite Rh3 in lipopolysaccharide-stimulated microglia: critical role of 5'-adenosine monophosphate-activated protein kinase signaling pathway.
PubMed: Effect of white, red and black ginseng on physicochemical properties and ginsenosides.
PubMed: Effect of Fermented Red Ginseng Extract Enriched in Ginsenoside Rg3 on the Differentiation and Mineralization of Preosteoblastic MC3T3-E1 Cells.
PubMed: [Effect of clopidogrel on plasma protein binding rate of ginsenosides: a liquid chromatography-mass spectrometry-based study].
PubMed: Biosynthesis and biotechnological production of ginsenosides.
PubMed: Direct infusion MS-based lipid profiling reveals the pharmacological effects of compound K-reinforced ginsenosides in high-fat diet induced obese mice.
PubMed: 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes.
PubMed: Characterization of oxygenated metabolites of ginsenoside Rb1 in plasma and urine of rat.
PubMed: Pharmacological treatment of pure stress urinary incontinence: a narrative review.
PubMed: [Research on chemical reactions during ginseng processing].
PubMed: Bioconversion of Ginsenosides from Red Ginseng Extract Using Candida allociferrii JNO301 Isolated from Meju.
PubMed: A gut microbial metabolite of ginsenosides, compound K, induces intestinal glucose absorption and Na(+) /glucose cotransporter 1 gene expression through activation of cAMP response element binding protein.
PubMed: Ginsenoside Rc promotes anti-adipogenic activity on 3T3-L1 adipocytes by down-regulating C/EBPα and PPARγ.
PubMed: Metabolomic evaluation of ginsenosides distribution in Panax genus (Panax ginseng and Panax quinquefolius) using multivariate statistical analysis.
PubMed: Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells.
PubMed: Ginsenoside Re protects methamphetamine-induced mitochondrial burdens and proapoptosis via genetic inhibition of protein kinase C δ in human neuroblastoma dopaminergic SH-SY5Y cell lines.
PubMed: Red ginseng extract promotes the hair growth in cultured human hair follicles.
PubMed: Ginsenoside Rb1 prevents H2O2-induced HUVEC senescence by stimulating sirtuin-1 pathway.
PubMed: Ginsenoside F1 attenuates hyperpigmentation in B16F10 melanoma cells by inducing dendrite retraction and activating Rho signalling.
PubMed: Enzymatic transformation of ginsenosides in Korean Red Ginseng (Panax ginseng Meyer) extract prepared by Spezyme and Optidex.
PubMed: Changes in ginsenoside compositions and antioxidant activities of hydroponic-cultured ginseng roots and leaves with heating temperature.
PubMed: Detoxifying effect of fermented black ginseng on H2O2-induced oxidative stress in HepG2 cells.
PubMed: Microbial ketonization of ginsenosides F1 and C-K by Lactobacillus brevis.
PubMed: Qualitative and quantitative analysis on aroma characteristics of ginseng at different ages using E-nose and GC-MS combined with chemometrics.
PubMed: Influence of aging process on the bioactive components and antioxidant activity of ginseng (Panax ginseng L.).
PubMed: Bioavailability of ginsenosides from white and red ginsengs in the simulated digestion model.
PubMed: The ginsenoside 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol induces autophagy and apoptosis in human melanoma via AMPK/JNK phosphorylation.
PubMed: Quantitative comparison and metabolite profiling of saponins in different parts of the root of Panax notoginseng.
PubMed: Saponins in the genus Panax L. (Araliaceae): a systematic review of their chemical diversity.
PubMed: Taste characteristics based quantitative and qualitative evaluation of ginseng adulteration.
PubMed: Stereospecificity of ginsenoside Rg3 in the promotion of cellular immunity in hepatoma H22-bearing mice.
PubMed: Ginsenoside Rb1 eliminates HIV-1 (D3)-transduced cytoprotective human macrophages by inhibiting the AKT pathway.
PubMed: Ginsenoside-free molecules from steam-dried ginseng berry promote ethanol metabolism: an alternative choice for an alcohol hangover.
PubMed: A well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving Parkinson's disease.
PubMed: Rapeseed oil and ginseng saponins work synergistically to enhance Th1 and Th2 immune responses induced by the foot-and-mouth disease vaccine.
PubMed: Identification and characterization of a ginsenoside-transforming β-glucosidase from Pseudonocardia sp. Gsoil 1536 and its application for enhanced production of minor ginsenoside Rg2(S).
PubMed: Quantitative Analysis of Panax ginseng by FT-NIR Spectroscopy.
PubMed: Ginsenoside Rb1 improves energy metabolism in the skeletal muscle of an animal model of postoperative fatigue syndrome.
PubMed: 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol suppresses UV-Induced MMP-1 expression through AMPK-mediated mTOR inhibition as a downstream of the PKA-LKB1 pathway.
PubMed: Expression of antiviral cytokines in Crandell-Reese feline kidney cells pretreated with Korean red ginseng extract or ginsenosides.
PubMed: Protective effects of ginsenoside Rb1 on septic rats and its mechanism.
PubMed: [Major hypoglycemic ingredients of Panax notoginseng saponins for treating diabetes].
PubMed: Bioconversion of ginsenosides in the american ginseng ( xī yáng shēn) extraction residue by fermentation with lingzhi ( líng zhī, ganoderma lucidum).
PubMed: Anticarcinogenic effects of products of heat-processed ginsenoside Re, a major constituent of ginseng berry, on human gastric cancer cells.
PubMed: Effects and mechanisms of ginseng and ginsenosides on cognition.
PubMed: Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.
PubMed: Effects of compound K on hyperglycemia and insulin resistance in rats with type 2 diabetes mellitus.
PubMed: Ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI-H716 cells via bile acid receptor activation.
PubMed: Subacute oral toxicity study of korean red ginseng extract in sprague-dawley rats.
PubMed: Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3.
PubMed: Effects of ginseol k-g3, an Rg3-enriched fraction, on scopolamine-induced memory impairment and learning deficit in mice.
PubMed: Transformation of ginsenosides from notoginseng by artificial gastric juice can increase cytotoxicity toward cancer cells.
PubMed: Quality characteristics and ginsenosides composition of ginseng-yakju according to the particle size of ginseng powder.
PubMed: Esterification enhanced intestinal absorption of ginsenoside Rh2 in Caco-2 cells without impacts on its protective effects against H₂O₂-induced cell injury in human umbilical vein endothelial cells (HUVECs).
PubMed: Mass spectrometry imaging: applications to food science.
PubMed: Characterization of a ginsenoside-transforming β-glucosidase from Paenibacillus mucilaginosus and its application for enhanced production of minor ginsenoside F₂.
PubMed: Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters.
PubMed: Red ginseng (Panax ginseng) decreases isoproterenol-induced cardiac injury via antioxidant properties in porcine.
PubMed: YY162 prevents ADHD-like behavioral side effects and cytotoxicity induced by Aroclor1254 via interactive signaling between antioxidant potential, BDNF/TrkB, DAT and NET.
PubMed: Evaluation of antibacterial and anti-inflammatory activities of less polar ginsenosides produced from polar ginsenosides by heat-transformation.
PubMed: Enzyme-modified Panax ginseng inhibits UVB-induced skin aging through the regulation of procollagen type I and MMP-1 expression.
PubMed: 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in NC/Nga mice.
PubMed: Long-term administration of ginsenoside Rh1 enhances learning and memory by promoting cell survival in the mouse hippocampus.
PubMed: Characteristic study on the chemical components of Korean curved ginseng products.
PubMed: Peripheral immunomodulation with ginsenoside Rg1 ameliorates neuroinflammation-induced behavioral deficits in rats.
PubMed: Influence of gastrointestinal digestion and edible plant combination on oral bioavailability of triterpene saponins, using a biomimetic digestion and absorption system and determination by HPLC.
PubMed: Renoprotective effects of Maillard reaction products generated during heat treatment of ginsenoside Re with leucine.
PubMed: Ginsenoside rb1 modulates level of monoamine neurotransmitters in mice frontal cortex and cerebellum in response to immobilization stress.
PubMed: Biotransformation of ginsenoside Rd in the ginseng extraction residue by fermentation with lingzhi (Ganoderma lucidum).
PubMed: Simultaneous determination of seven ginsenosides in Du Shen Tang decoction by rapid resolution liquid chromatography (RRLC) coupled with tandem mass spectrometry.
PubMed: Updating chemical profiling of red ginseng via the elucidation of two geometric isomers of ginsenosides Rg9 and Rg10.
PubMed: Efficient thermal deglycosylation of ginsenoside Rd and its contribution to the improved anticancer activity of ginseng.
PubMed: Ginsenoside Rh2 improves learning and memory in mice.
PubMed: Red ginseng protects against gentamicin-induced balance dysfunction and hearing loss in rats through antiapoptotic functions of ginsenoside Rb1.
PubMed: Reduction of hepatitis A virus on FRhK-4 cells treated with Korean red ginseng extract and ginsenosides.
PubMed: A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food.
PubMed: Enhancement of protective immune response to recombinant Toxoplasma gondii ROP18 antigen by ginsenoside Re.
PubMed: Compound K induces apoptosis of bladder cancer T24 cells via reactive oxygen species-mediated p38 MAPK pathway.
PubMed: A new protopanaxadiol-type ginsenoside from the roots of Panax notoginseng.
PubMed: Mass production of the ginsenoside Rg3(S) through the combinative use of two glycoside hydrolases.
PubMed: High-pressure processing as emergent technology for the extraction of bioactive ingredients from plant materials.
PubMed: Dual-index evaluation of character changes in Panax ginseng C. A. Mey stored in different conditions.
PubMed: Effects of Korean red ginseng extract on acute renal failure induced by gentamicin and pharmacokinetic changes by metformin in rats.
PubMed: Ginseng panaxoside Rb1 reduces body weight in diet-induced obese mice.
PubMed: Compound K is able to ameliorate the impaired cognitive function and hippocampal neurogenesis following chemotherapy treatment.
PubMed: The effect of extrusion conditions on the acidic polysaccharide, ginsenoside contents and antioxidant properties of extruded Korean red ginseng.
PubMed: The bioavailability of red ginseng extract fermented by Phellinus linteus.
PubMed: Comparison of Ginsenoside and Phenolic Ingredient Contents in Hydroponically-cultivated Ginseng Leaves, Fruits, and Roots.
PubMed: Effects of Panax ginseng in Neurodegenerative Diseases.
PubMed: UPLC-Q-TOF-MS/MS Analysis for Steaming Times-dependent Profiling of Steamed Panax quinquefolius and Its Ginsenosides Transformations Induced by Repetitious Steaming.
PubMed: A formulated red ginseng extract upregulates CHOP and increases TRAIL-mediated cytotoxicity in human hepatocellular carcinoma cells.
PubMed: Diabetes-ameliorating effects of fermented red ginseng and causal effects on hormonal interactions: testing the hypothesis by multiple group path analysis.
PubMed: [Discussion on correlation between preparation, in vivo conversion process and potential structure-activity relationship of ginsenoside].
PubMed: Panax ginseng extract rich in ginsenoside protopanaxatriol offers combinatorial effects in nitric oxide production via multiple signaling pathways.
PubMed: Rapid chemical profiling of saponins in the flower buds of Panax notoginseng by integrating MCI gel column chromatography and liquid chromatography/mass spectrometry analysis.
PubMed: Profiling the ginsenosides of three ginseng products by LC-Q-TOF/MS.
PubMed: Determination of ginsenoside content in Panax ginseng C.A. Meyer and Panax quinquefolius L. root materials and finished products by high-performance liquid chromatography with ultraviolet absorbance detection: interlaboratory study.
PubMed: Lactobacillus yonginensis sp. nov., a lactic acid bacterium with ginsenoside converting activity isolated from Kimchi.
PubMed: Cultivated ginseng inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice and TNF-α/IFN-γ-induced TARC activation in HaCaT cells.
PubMed: Increase in antioxidant and anticancer effects of ginsenoside Re-lysine mixture by Maillard reaction.
PubMed: Microbial transformation of ginsenoside Rb1 to compound K by Lactobacillus paralimentarius.
PubMed: Lactobacillus ginsenosidimutans sp. nov., isolated from kimchi with the ability to transform ginsenosides.
PubMed: Research and development of the effective components of panaxdiol saponin as new Chinese patent medicine for treating hemocytopenia.
PubMed: [Effect of inorganic fertilizer on quality of Panax ginseng].
PubMed: Bioconversion of ginsenoside Rc into Rd by a novel α-L-arabinofuranosidase, Abf22-3 from Leuconostoc sp. 22-3: cloning, expression, and enzyme characterization.
PubMed: Identification of the beta-glucosidase gene from Bifidobacterium animalis subsp. lactis and its expression in B. bifidum BGN4.
PubMed: Metabolite profiling of ginsenoside Re in rat urine and faeces after oral administration.
PubMed: Chemical differentiation of two taste variants of Gynostemma pentaphyllum by using UPLC-Q-TOF-MS and HPLC-ELSD.
PubMed: Implication of the stereoisomers of ginsenoside derivatives in the antiproliferative effect of HSC-T6 cells.
PubMed: Fermenting red ginseng enhances its safety and efficacy as a novel skin care anti-aging ingredient: in vitro and animal study.
PubMed: Metabonomics approach to assessing the modulatory effects of St John's wort, ginsenosides, and clomipramine in experimental depression.
PubMed: Rapid differentiation of Panax ginseng and Panax quinquefolius by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed: Absorption mechanism of ginsenoside compound K and its butyl and octyl ester prodrugs in Caco-2 cells.
PubMed: Ginsenosides Rb₁ and Rd regulate proliferation of mature keratinocytes through induction of p63 expression in hair follicles.
PubMed: Studies on the chemical transformation of 20(S)-protopanaxatriol (PPT)-type ginsenosides R(e), R(g2), and R(f) using rapid resolution liquid chromatography coupled with quadruple-time-of-flight mass spectrometry (RRLC-Q-TOF-MS).
PubMed: Increase in antioxidant effect of ginsenoside Re-alanine mixture by Maillard reaction.
PubMed: Determination of 22 ginsenosides in ginseng products using ultra-high-performance liquid chromatography.
PubMed: Influence of sulphur-fumigation on the quality of white ginseng: a quantitative evaluation of major ginsenosides by high performance liquid chromatography.
PubMed: Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice.
PubMed: Ginsenoside Re ameliorates inflammation by inhibiting the binding of lipopolysaccharide to TLR4 on macrophages.
PubMed: Steaming-induced chemical transformations and holistic quality assessment of red ginseng derived from Panax ginseng by means of HPLC-ESI-MS/MS(n)-based multicomponent quantification fingerprint.
PubMed: Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: a 26-week intramuscular repeated administration study in rats.
PubMed: Microbial transformation of ginsenoside Rg3 to ginsenoside Rh2 by Esteya vermicola CNU 120806.
PubMed: Highly selective microbial transformation of major ginsenoside Rb1 to gypenoside LXXV by Esteya vermicola CNU120806.
PubMed: Ginsenoside Rg3 reduces lipid accumulation with AMP-Activated Protein Kinase (AMPK) activation in HepG2 cells.
PubMed: Anti-diabetic effect of ginsenoside Rb(3) in alloxan-induced diabetic mice.
PubMed: Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced apoptosis in hepatoma cells through mitochondrial signaling pathways.
PubMed: Modification of ginseng flavors by bitter compounds found in chocolate and coffee.
PubMed: Ginsenoside rich fraction of Panax ginseng C.A. Meyer improve feeding behavior following radiation-induced pica in rats.
PubMed: Enzymatic biotransformation of ginsenoside Rb1 to compound K by recombinant β-glucosidase from Microbacterium esteraromaticum.
PubMed: Inhibition of inflammations and macrophage activation by ginsenoside-Re isolated from Korean ginseng (Panax ginseng C.A. Meyer).
PubMed: Ginsenoside Rb1 inhibits osteoclastogenesis by modulating NF-κB and MAPKs pathways.
PubMed: Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase.
PubMed: Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.
PubMed: Ginsenoside Rg3 enhances the chemosensitivity of tumors to cisplatin by reducing the basal level of nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1/NAD(P)H quinone oxidoreductase-1 and prevents normal tissue damage by scavenging cisplatin-induced intracellular reactive oxygen species.
PubMed: Changes in the Contents of Prosapogenin in the Red Ginseng (Panax ginseng) Depending on Steaming Batches.
PubMed: Comparative Study of White and Steamed Black Panax ginseng, P. quinquefolium, and P. notoginseng on Cholinesterase Inhibitory and Antioxidative Activity.
PubMed: Matrix solid phase dispersion extraction of ginsenosides in the leaves of Panax ginseng C.M. Mey.
PubMed: Antiviral effect of korean red ginseng extract and ginsenosides on murine norovirus and feline calicivirus as surrogates for human norovirus.
PubMed: Ginsenoside Rb3 exerts antidepressant-like effects in several animal models.
PubMed: Lipid metabolic effect of Korean red ginseng extract in mice fed on a high-fat diet.
PubMed: Ginsenoside Rb1 inhibits cell activation and liver fibrosis in rat hepatic stellate cells.
PubMed: Ginsenoside metabolite compound K differentially antagonizing tumor necrosis factor-α-induced monocyte-endothelial trafficking.
PubMed: Preventive effects of protopanaxadiol and protopanaxatriol ginsenosides on liver inflammation and apoptosis in hyperlipidemic apoE KO mice.
PubMed: Changes of ginsenoside content by mushroom mycelial fermentation in red ginseng extract.
PubMed: Subchronic toxicity studies with ginsenoside compound K delivered to dogs via intravenous administration.
PubMed: Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: a 26-week intramuscular repeated administration study in Beagle dogs.
PubMed: Sensory properties of ginseng solutions modified by masking agents.
PubMed: Porosity changes and retention of ginsenosides in North American ginseng root using different dehydration processes.
PubMed: Ginsenoside Rb1 inhibits proliferation and inflammatory responses in rat aortic smooth muscle cells.
PubMed: Effect of ginsenosides Rg3 and Re on glucose transport in mature 3T3-L1 adipocytes.
PubMed: Long-term ginsenoside administration prevents memory loss in aged female C57BL/6J mice by modulating the redox status and up-regulating the plasticity-related proteins in hippocampus.
PubMed: Inhibition of JAK1/STAT3 signaling mediates compound K-induced apoptosis in human multiple myeloma U266 cells.
PubMed: Flow injection mass spectroscopic fingerprinting and multivariate analysis for differentiation of three Panax species.
PubMed: A comparison between high hydrostatic pressure extraction and heat extraction of ginsenosides from ginseng (Panax ginseng CA Meyer).
PubMed: Red notoginseng: higher ginsenoside content and stronger anticancer potential than Asian and American ginseng.
PubMed: Ginsenoside Rb1 improves spatial learning and memory by regulation of cell genesis in the hippocampal subregions of rats.
PubMed: Interactions between various microbes and ginseng botanicals.
PubMed: Oral administration of ginsenoside Rh1 inhibits the development of atopic dermatitis-like skin lesions induced by oxazolone in hairless mice.
PubMed: Differentiation of Panax quinquefolius grown in the USA and China using LC/MS-based chromatographic fingerprinting and chemometric approaches.
PubMed: Study on the interactions between ginsenosides and lysozyme under acidic condition by ESI-MS and molecular docking.
PubMed: Protopanaxatriol-type ginsenosides from the root of Panax ginseng.
PubMed: Hormonal action of plant derived and anthropogenic non-steroidal estrogenic compounds: phytoestrogens and xenoestrogens.
PubMed: Sensory profile of a model energy drink with varying levels of functional ingredients-caffeine, ginseng, and taurine.
PubMed: Antiobesity and antihyperglycemic effects of ginsenoside Rb1 in rats.
PubMed: Antihepatocarcinoma activity of lactic acid bacteria fermented Panax notoginseng.
PubMed: Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from black ginseng.
PubMed: Ginsenoside composition and antiproliferative activities of explosively puffed ginseng (Panax ginseng C.A. Meyer).
PubMed: Short communication: Influence of pasteurization on the active compounds in medicinal plants to be used in dairy products.
PubMed: Production of spherical granule from viscous red ginseng extracts for improving product fluency and preservation and its physicochemical properties.
PubMed: Effect and mechanism of ginsenosides CK and Rg1 on stimulation of glucose uptake in 3T3-L1 adipocytes.
PubMed: Anti-diabetic effects of Panax notoginseng saponins and its major anti-hyperglycemic components.
PubMed: Red ginseng saponin extract attenuates murine collagen-induced arthritis by reducing pro-inflammatory responses and matrix metalloproteinase-3 expression.
PubMed: Characterization of metabolism and in vitro permeability study of notoginsenoside R1 from Radix notoginseng.
PubMed: [Effect of different treatment methods on quality of American ginseng roots].
PubMed: Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases.
PubMed: The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart.
PubMed: [Microorganisms of special herb-glycosidases and their fermentation, enzyme properties].
PubMed: [Effects of Panax notoginseng saponins on anti-hyperglycemic, anti-obese and prevention from kidney pathological changes in KK-Ay mice].
PubMed: Korean red ginseng extract does not cause embryo-fetal death or abnormalities in mice.
PubMed: Microbial conversion of rare ginsenoside Rf to 20(S)-protopanaxatriol by Aspergillus niger.
PubMed: Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin: a randomized, double-blind, placebo-controlled study.
PubMed: Red ginseng extract protects against aflatoxin B1 and fumonisins-induced hepatic pre-cancerous lesions in rats.
PubMed: Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism.
PubMed: Application of gamma irradiation in ginseng for both photodegradation of pesticide pentachloronitrobenzene and microbial decontamination.
PubMed: Compound K protects MIN6N8 pancreatic beta-cells against palmitate-induced apoptosis through modulating SAPK/JNK activation.
PubMed: Evaluation of nanofabricated ginseng extract powders.
PubMed: Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells.
PubMed: Microwave degradation of floatation-enriched ginsenoside extract from Panax quinquefolium L. leaf.
PubMed: Antioxidant and apoptotic effects of korean white ginseng extracted with the same ratio of protopanaxadiol and protopanaxatriol saponins in human hepatoma HepG2 cells.
PubMed: Effect of compound K, a metabolite of ginseng saponin, combined with gamma-ray radiation in human lung cancer cells in vitro and in vivo.
PubMed: Pharmacokinetic characterization of ginsenoside Rh2, an anticancer nutrient from ginseng, in rats and dogs.
PubMed: Effects of red ginseng extract on UVB irradiation-induced skin aging in hairless mice.
PubMed: Long-term ginsenoside administration prevents memory impairment in aged C57BL/6J mice by up-regulating the synaptic plasticity-related proteins in hippocampus.
PubMed: [Experimental study for the anti-fatigue effect of ginseng general ginsenosides P.E. in vivo].
PubMed: Simultaneous quantification of 19 ginsenosides in black ginseng developed from Panax ginseng by HPLC-ELSD.
PubMed: Improvement of memory in mice and increase of hippocampal excitability in rats by ginsenoside Rg1's metabolites ginsenoside Rh1 and protopanaxatriol.
PubMed: Detection of adulteration of notoginseng root extract with other panax species by quantitative HPLC coupled with PCA.
PubMed: Effect of a putative ERalpha antagonist, MPP, on food intake in cycling and ovariectomized rats.
PubMed: Effects of extrusion process variables on extractable ginsenosides in wheat-ginseng extrudates.
PubMed: Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells.
PubMed: Long-term ginsenoside consumption prevents memory loss in aged SAMP8 mice by decreasing oxidative stress and up-regulating the plasticity-related proteins in hippocampus.
PubMed: Role of ginsenoside Rd in inhibiting 26S proteasome activity.
PubMed: Comparison of the effects of Korean ginseng and heat-processed Korean ginseng on diabetic oxidative stress.
PubMed: Ginsenosides Rb1 and Rg1 suppress triglyceride accumulation in 3T3-L1 adipocytes and enhance beta-cell insulin secretion and viability in Min6 cells via PKA-dependent pathways.
PubMed: Optimization of lipase-catalyzed synthesis of ginsenoside Rb1 esters using response surface methodology.
PubMed: A randomized controlled crossover trial of the effect of ginseng consumption on the immune response to moderate exercise in healthy sedentary men.
PubMed: Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways.
PubMed: Optimization of ginsenosides hydrolyzing beta-glucosidase production from Aspergillus niger using response surface methodology.
PubMed: Ginsenosides chemistry, biosynthesis, analysis, and potential health effects.
PubMed: Analysis of ginsenosides in Panax ginseng in high pressure microwave-assisted extraction.
PubMed: Ginsenoside Rd prevents and rescues rat intestinal epithelial cells from irradiation-induced apoptosis.
PubMed: Effect of CVT-E002 (COLD-fX) versus a ginsenoside extract on systemic and gut-associated immune function.
PubMed: Effects of ginsenosides on organogenesis and expression of glutathione peroxidase genes in cultured rat embryos.
PubMed: Inhibitory effects of ginsenosides from the root of Panax ginseng on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation, and translocation of cytosolic compounds to plasma membrane in human neutrophils.
PubMed: The protective effects of ginsenosides on human erythrocytes against hemin-induced hemolysis.
PubMed: Characterizing the mechanism for ginsenoside-induced cytotoxicity in cultured leukemia (THP-1) cells.
PubMed: Compound K enhances insulin secretion with beneficial metabolic effects in db/db mice.
PubMed: American ginseng berry juice intake reduces blood glucose and body weight in ob/ob mice.
PubMed: Anti-obesity effects of ginsenoside Rh2 are associated with the activation of AMPK signaling pathway in 3T3-L1 adipocyte.
PubMed: Transformation of bioactive compounds by Fusarium sacchari fungus isolated from the soil-cultivated ginseng.
PubMed: Protective effects of total saponins from stem and leaf of Panax ginseng against cyclophosphamide-induced genotoxicity and apoptosis in mouse bone marrow cells and peripheral lymphocyte cells.
PubMed: Protective effect of heat-processed American ginseng against diabetic renal damage in rats.
PubMed: The inhibitory effects of garlic and Panax ginseng extract standardized with ginsenoside Rg3 on the genotoxicity, biochemical, and histological changes induced by ethylenediaminetetraacetic acid in male rats.
PubMed: Quantification of two polyacetylenes in Radix Ginseng and roots of related Panax species using a gas chromatography-mass spectrometric method.
PubMed: Eastern blotting and immunoaffinity concentration using monoclonal antibody for ginseng saponins in the field of traditional chinese medicines.
PubMed: Protective effect of ginseng on cytokine-induced apoptosis in pancreatic beta-cells.
PubMed: Weight gain reduction in mice fed Panax ginseng saponin, a pancreatic lipase inhibitor.
PubMed: Protective effect of steamed American ginseng (Panax quinquefolius L.) on V79-4 cells induced by oxidative stress.
PubMed: Effect of ginsenosides on glucose uptake in human Caco-2 cells is mediated through altered Na+/glucose cotransporter 1 expression.
PubMed: Purification and characterization of new special ginsenosidase hydrolyzing multi-glycisides of protopanaxadiol ginsenosides, ginsenosidase type I.
PubMed: Studies of selected plant raw materials as alternative sources of triterpenes of oleanolic and ursolic acid types.
PubMed: Steamed American ginseng berry: ginsenoside analyses and anticancer activities.
PubMed: Biotransformation of Korean Panax ginseng by Pectinex.
PubMed: Simultaneous determination of ginsenosides and polyacetylenes in American ginseng root (Panax quinquefolium L.) by high-performance liquid chromatography.
PubMed: Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models.
PubMed: Copper-induced changes in the growth, oxidative metabolism, and saponin production in suspension culture roots of Panax ginseng in bioreactors.
PubMed: Korean red ginseng rootlets decrease acute postprandial glycemia: results from sequential preparation- and dose-finding studies.
PubMed: Study on the nitric oxide scavenging effects of ginseng and its compounds.
PubMed: Saponins composition in American ginseng leaf and berry assayed by high-performance liquid chromatography.
PubMed: Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells.
PubMed: Simplified extraction of ginsenosides from American ginseng (Panax quinquefolius L.) for high-performance liquid chromatography-ultraviolet analysis.
PubMed: Transformation of ginsenosides Rb2 and Rc from Panax ginseng by food microorganisms.
PubMed: Effects of population, age, and cultivation methods on ginsenoside content of wild American ginseng (Panax quinquefolium).
PubMed: Genetic diversity and variation of saponin contents in Panax notoginseng roots from a single farm.
PubMed: Transformation of ginsenosides Rb1 and Re from Panax ginseng by food microorganisms.
PubMed: Effects of ginsenoside Rg1 on postimplantation rat and mouse embryos cultured in vitro.
PubMed: American ginseng berry extract and ginsenoside Re attenuate cisplatin-induced kaolin intake in rats.
PubMed: Enhancement of insulin sensitivity in adipocytes by ginger.
PubMed: Determination of ginsenosides Rb1, Rc, and Re in different dosage forms of ginseng by negative ion electrospray liquid chromatography-mass spectrometry.
PubMed: Mechanistic studies on protopanaxadiol, Rh2, and ginseng (Panax quinquefolius) extract induced cytotoxicity in intestinal Caco-2 cells.
PubMed: Effects of inoculum conditions on growth of hairy roots of Panax ginseng C.A. Meyer.
PubMed: Ginsenosides 20(S)-protopanaxadiol and Rh2 reduce cell proliferation and increase sub-G1 cells in two cultured intestinal cell lines, Int-407 and Caco-2.
PubMed: Evaluation of the efficiency of three different solvent systems to extract triterpene saponins from roots of Panax quinquefolius using high-performance liquid chromatography.
PubMed: Determination of ginsenosides (ginseng saponins) in dry root powder from Panax ginseng, Panax quinquefolius, and selected commercial products by liquid chromatography: interlaboratory study.
PubMed: Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants.
PubMed: Generation of ginsenosides Rg3 and Rh2 from North American ginseng.
PubMed: Chemical assessment of roots of Panax notoginseng in China: regional and seasonal variations in its active constituents.
PubMed: Phytochemistry of wild populations of Panax quinquefolius L. (North American ginseng).
PubMed: Isolation of dammarane saponins from Panax notoginseng by high-speed counter-current chromatography.
PubMed: Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb(1) (ginseng) and parthenolide (feverfew).
PubMed: In vitro study of the relationship between the structure of ginsenoside and its antioxidative or prooxidative activity in free radical induced hemolysis of human erythrocytes.
PubMed: Optimization of microwave-assisted extraction (MAP) for ginseng components by response surface methodology.
PubMed: Committee on food nutrition. Nonvitamin micronutrients.
PubMed: Peripheral blood mononuclear cell production of TNF-alpha in response to North American ginseng stimulation.
PubMed: Structure-function relationship exists for ginsenosides in reducing cell proliferation and inducing apoptosis in the human leukemia (THP-1) cell line.
PubMed: Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component.
PubMed: Purification and characterization of ginsenoside-alpha-L-rhamnosidase.
PubMed: Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities.
PubMed: Variability in commercial ginseng products: an analysis of 25 preparations.
PubMed: DNA identification of commercial ginseng samples.
PubMed: Antioxidant properties of a North American ginseng extract.
PubMed: Simultaneous quantification of ginsenosides in American ginseng (Panax quinquefolium) root powder by visible/near-infrared reflectance spectroscopy.
PubMed: Degradation of ginsenosides in American ginseng (Panax quinquefolium) extracts during microwave and conventional heating.
PubMed: Panax ginseng pharmacology: a nitric oxide link?
PubMed: Hypothalamic neuronal histamine modulates adaptive behavior and thermogenesis in response to endogenous pyrogen.
PubMed: Ginsenoside Rg1 modulates ingestive behavior and thermal response induced by interleukin-1 beta in rats.
PubMed: [Study on the nootropic mechanism of ginsenoside Rb1 and Rg1--influence on mouse brain development].
PubMed: Ginsenoside Rg1 prevents histaminergic modulation of rat adaptive behavior from elevation of ambient temperature.
PubMed: [Minor components in food plants--II. Triterpenoid saponins from Ullucus tuberosus].
PubMed: Attenuation of anorexia induced by heat or surgery during sustained administration of ginsenoside Rg1 into rat third ventricle.
PubMed: [Ginsenoside-Rb1 as a suppressor in central modulation of feeding in the rat].
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