gallium maltolate
gallium, tris[3-(hydroxy-\KO)-2-methyl-4H-pyran-4-onato-\KO4]- (OC-6-21)
 
Notes:
None found
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      Product(s):
      108560-70-9 Tris[3-(hydroxy-kappaO)-2-methyl-4H-pyran-4-onato-kappaO4]gallium 95%
       
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CAS Number: 108560-70-9Picture of molecule3D/inchi
FDA UNII: 17LEI49C2G
Molecular Weight: 445.03335000
Formula: C18 H15 Ga O9
NMR Predictor: Predict (works with chrome or firefox)
Category: cosmetic ingredient for skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
BOC Sciences
For experimental / research use only.
Tris[3-(hydroxy-kappaO)-2-methyl-4H-pyran-4-onato-kappaO4]gallium 95%
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for gallium maltolate usage levels up to:
 not for fragrance use.
 
Recommendation for gallium maltolate flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0108560709
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References:
NIST Chemistry WebBook: Search Inchi
Pubchem (sid): 312698258
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 gallium, tris[3-(hydroxy-\KO)-2-methyl-4H-pyran-4-onato-\KO4]- (OC-6-21)
tris(3-hydroxy-2-methyl-4H-pyran-4-onato)gallium(III)
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Articles:
PubMed: Serum and tissue concentrations of gallium after oral administration of gallium nitrate and gallium maltolate to neonatal calves.
PubMed: Gallium maltolate as an alternative to macrolides for treatment of presumed Rhodococcus equi pneumonia in foals.
PubMed: Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins.
PubMed: Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice.
PubMed: Comparison of the antimicrobial activities of gallium nitrate and gallium maltolate against Mycobacterium avium subsp. paratuberculosis in vitro.
PubMed: In vitro susceptibility of equine-obtained isolates of Corynebacterium pseudotuberculosis to gallium maltolate and 20 other antimicrobial agents.
PubMed: Efficacy of gallium maltolate against Lawsonia intracellularis infection in a rabbit model.
PubMed: Pharmacokinetics of gallium maltolate in Lawsonia intracellularis-infected and uninfected rabbits.
PubMed: Reduction in absorption of gallium maltolate in adult horses following oral administration with food: chemistry and pharmacokinetics.
PubMed: Synchrotron X-ray fluorescence microscopy of gallium in bladder tissue following gallium maltolate administration during urinary tract infection.
PubMed: Successful treatment of refractory postherpetic neuralgia with topical gallium maltolate: case report.
PubMed: Antimicrobial activity of gallium maltolate against Staphylococcus aureus and methicillin-resistant S. aureus and Staphylococcus pseudintermedius: An in vitro study.
PubMed: Evaluation of the efficacy of gallium maltolate for chemoprophylaxis against pneumonia caused by Rhodococcus equi infection in foals.
PubMed: Hepatocellular carcinoma detection by gallium scan and subsequent treatment by gallium maltolate: rationale and case study.
PubMed: Evaluation of the effect of gallium maltolate on fecal Salmonella shedding in cattle.
PubMed: Pharmacokinetics of gallium maltolate after intragastric administration in adult horses.
PubMed: Pharmacokinetics of an orally administered methylcellulose formulation of gallium maltolate in neonatal foals.
PubMed: In vitro antimicrobial activity of gallium maltolate against virulent Rhodococcus equi.
PubMed: Gallium maltolate: safety in neonatal foals following multiple enteral administrations.
PubMed: A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle cell lymphoma cells.
PubMed: In vitro activity of gallium maltolate against Staphylococci in logarithmic, stationary, and biofilm growth phases: comparison of conventional and calorimetric susceptibility testing methods.
PubMed: Gallium maltolate treatment eradicates Pseudomonas aeruginosa infection in thermally injured mice.
PubMed: Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability.
PubMed: Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals.
PubMed: Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate.
PubMed: Gallium maltolate is a promising chemotherapeutic agent for the treatment of hepatocellular carcinoma.
PubMed: Antimicrobial activity of gallium against virulent Rhodococcus equiin vitro and in vivo.
PubMed: Gallium in cancer treatment.
PubMed: Gateways to clinical trials.
PubMed: Gallium and other main group metal compounds as antitumor agents.
PubMed: Gateways to clinical trials.
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