crystallins
protein found in the fiber cells of vertebrate eye lenses
 
Notes:
None found
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CAS Number: 11046-99-4 
Category: cosmetic ingredient for skin and hair conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: hair conditioning
skin conditioning
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin and hair conditioning
Recommendation for crystallins usage levels up to:
 not for fragrance use.
 
Recommendation for crystallins flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
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References:
Pubchem (cas): 11046-99-4
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 protein found in the fiber cells of vertebrate eye lenses
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Articles:
PubMed: Anticataractogenesis Mechanisms of Curcumin and a Comparison of Its Degradation Products: An in Vitro Study.
PubMed: Tea Flavanols Block Advanced Glycation of Lens Crystallins Induced by Dehydroascorbic Acid.
PubMed: Impact of molecular and crystalline structures on in vitro digestibility of waxy rice starches.
PubMed: Carnosine ameliorates lens protein turbidity formations by inhibiting calpain proteolysis and ultraviolet C-induced degradation.
PubMed: The protection of bovine skeletal myofibrils from proteolytic damage post mortem by small heat shock proteins.
PubMed: Natural antioxidant biomolecules promises future nanomedicine based therapy for cataract.
PubMed: Small heat shock proteins and toughness in intermediate pHu beef.
PubMed: Aggregation and fibrillogenesis of proteins not associated with disease: a few case studies.
PubMed: Crystalline structure and thermal property characterization of chitin from Antarctic krill (Euphausia superba).
PubMed: A macrocyclic calpain inhibitor slows the development of inherited cortical cataracts in a sheep model.
PubMed: Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice.
PubMed: Proteome changes in the insoluble protein fraction of bovine Longissimus dorsi muscle as a result of low-voltage electrical stimulation.
PubMed: A novel two-stage tandem mass spectrometry approach and scoring scheme for the identification of O-GlcNAc modified peptides.
PubMed: Gene expression profiles in fetal and neonatal rat offspring of energy-restricted dams.
PubMed: Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats.
PubMed: Interaction of chaperone alpha-crystallin with unfolded state of alpha-amylase: Implications for reconstitution of the active enzyme.
PubMed: Inhibition of crystallin ascorbylation by nucleophilic compounds in the hSVCT2 mouse model of lenticular aging.
PubMed: Establishment of high-resolution FISH mapping system and its application for molecular cytogenetic characterization of chromosomes in newt, Cynops pyrrhogaster (Urodela, Amphibia).
PubMed: Immunochemical detection of glycated beta- and gamma-crystallins in lens and their circulating autoantibodies (IgG) in streptozocin induced diabetic rat.
PubMed: Influence of soy aglycon isoflavones on bone-related traits and lens protein characteristics of ovariectomized rats and bioactivity performance of osteoprogenitor cells.
PubMed: Astaxanthin protects against oxidative stress and calcium-induced porcine lens protein degradation.
PubMed: Casein proteins as molecular chaperones.
PubMed: Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin.
PubMed: FT-Raman spectroscopic investigation of lens proteins of tilapia treated with dietary vitamin E.
PubMed: Dietary sugar and salt represent real risk factors for cataract development.
PubMed: Effect of long-term dietary manipulation on the aggregation of rat lens crystallins: role of alpha-crystallin chaperone function.
PubMed: Protein glycation, diabetes, and aging.
PubMed: Non-enzymatic glycation of lens proteins and haemoglobin-inhibition by pyruvate: an in-vivo study.
PubMed: Crystallization and preliminary X-ray crystallographic analysis of NADPH: azodicarbonyl/quinone oxidoreductase, a plant zeta-crystallin.
PubMed: A novel NADPH:diamide oxidoreductase activity in arabidopsis thaliana P1 zeta-crystallin.
PubMed: Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo.
PubMed: Defects of copper deficiency in rats are modified by dietary treatments that affect glycation.
PubMed: Antioxidants and the prevention of cataract.
PubMed: Modelling cortical cataractogenesis. XII: Supplemental vitamin A treatment reduces gamma-crystallin leakage from lenses in diabetic rats.
PubMed: Is the lens canned?
PubMed: Modeling cortical cataractogenesis: IX. Activity of vitamin E and esters in preventing cataracts and gamma-crystallin leakage from lenses in diabetic rats.
PubMed: Accelerated age-related browning of human collagen in diabetes mellitus.
PubMed: Maillard reactions involving proteins and carbohydrates in vivo: relevance to diabetes mellitus and aging.
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