hydrolyzed actin
hydrolysis of actin, composed primarily of proteins, peptides and amino acids
 
Notes:
None found
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CAS Number: 222400-31-9 
Category: cosmetic ingredient for skin and hair conditioning
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: hair conditioning
skin conditioning
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin and hair conditioning
Recommendation for hydrolyzed actin usage levels up to:
 not for fragrance use.
 
Recommendation for hydrolyzed actin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
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References:
Pubchem (cas): 222400-31-9
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Other Information:
HMDB (The Human Metabolome Database): Search
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 actins hydrolyzates
 hydrolysis of actin, composed primarily of proteins, peptides and amino acids
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Articles:
PubMed: Unusual dynamics of the divergent malaria parasite PfAct1 actin filament
PubMed: Actin polymerization and ATP hydrolysis
PubMed: Actin polymerization: regulation by divalent metal ion and nucleotide binding, ATP hydrolysis and binding of myosin
PubMed: Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization
PubMed: Mechanism of K+-induced actin assembly
PubMed: Association of actin with the nuclear matrix from bovine lymphocytes
PubMed: Identification of two proteins (actin-binding protein and P235) that are hydrolyzed by endogenous Ca2+-dependent protease during platelet aggregation
PubMed: A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
PubMed: Noncooperative stabilization effect of phalloidin on ADP.BeFx- and ADP.AlF4-actin filaments
PubMed: Covalent binding of ATPgammaS to the nucleotide-binding site in S14C-actin
PubMed: Direct evidence for ADP-Pi-F-actin as the major intermediate in ATP-actin polymerization. Rate of dissociation of Pi from actin filaments
PubMed: Actin polymerization is controlled by residue size at position 204
PubMed: Glutamyl phosphate is an activated intermediate in actin crosslinking by actin crosslinking domain (ACD) toxin
PubMed: Identification of actin-binding protein as the protein linking the membrane skeleton to glycoproteins on platelet plasma membranes
PubMed: Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
PubMed: Actin-activated adenosine triphosphatase activity of native and N-ethylmaleimide-modified cardiac myosin from normal and thyrotoxic rabbits
PubMed: Spectrin is associated with membrane-bound actin filaments in platelets and is hydrolyzed by the Ca2+-dependent protease during platelet activation
PubMed: Myosin subfragment-1 interacts with two G-actin molecules in the absence of ATP
PubMed: The Isolation of Actin from Pea Roots by DNase I Affinity Chromatography
PubMed: A SAC Phosphoinositide Phosphatase Controls Rice Development via Hydrolyzing PI4P and PI(4,5)P(2)
PubMed: Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB
PubMed: Hydrolysis of cytoskeletal proteins by the Ca2+-dependent protease during platelet activation
PubMed: Partially hydrolyzed guar gum enhances colonic epithelial wound healing via activation of RhoA and ERK1/2
PubMed: Structural dynamics of actin during active interaction with myosin: different effects of weakly and strongly bound myosin heads
PubMed: Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments
PubMed: The influence of surfactants and hydrolyzed proteins on keratinocytes viability and elasticity
PubMed: Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus
PubMed: Mechanism of interaction of Acanthamoeba actophorin (ADF/Cofilin) with actin filaments
PubMed: Nucleotide hydrolysis in cytoskeletal assembly
PubMed: ATP hydrolysis on actin-related protein 2/3 complex causes debranching of dendritic actin arrays
PubMed: Inorganic polyphosphate hydrolysis catalyzed by skeletal muscular actomyosin complexes is uncoupled with motility
PubMed: Phytate hydrolysate induces circumferential F-actin ring formation at cell-cell contacts by a Rho-associated kinase-dependent mechanism in colorectal cancer HT-29 cells
PubMed: Stem cell adhesion and proliferation on hydrolyzed poly(butylene succinate)/?-tricalcium phosphate composites
PubMed: Proteolytic specificity of cathepsin D on bovine F-actin
PubMed: How ATP hydrolysis controls filament assembly from profilin-actin: implication for formin processivity
PubMed: Phosphorylation of Acanthamoeba actophorin (ADF/cofilin) blocks interaction with actin without a change in atomic structure
PubMed: The association of actin and myosin in the presence of gamma-amido-ATP proceeds mainly via a complex with myosin in the closed conformation
PubMed: Kinetics of myosin subfragment-1-induced condensation of G-actin into oligomers, precursors in the assembly of F-actin-S1. Role of the tightly bound metal ion and ATP hydrolysis
PubMed: Myosin subfragment 1 inhibits dissociation of nucleotide and calcium from G-actin
PubMed: Proteolytic activity of arginine esterase from dog seminal plasma towards actin and other structural proteins. Comparison with trypsin and kallikrein
PubMed: Myosin subfragment 1 activates ATP hydrolysis on Mg(2+)-G-actin
PubMed: Continuous monitoring of Pi release following nucleotide hydrolysis in actin or tubulin assembly using 2-amino-6-mercapto-7-methylpurine ribonucleoside and purine-nucleoside phosphorylase as an enzy
PubMed: Disruption of actin cytoskeleton enhanced cytokine synthesis of splenocytes stimulated with beta-glucan from the cauliflower medicinal mushroom, Sparassis crispa Wulf.:Fr. (higher Basidiomycetes) in
PubMed: Sliding distance per ATP molecule hydrolyzed by myosin heads during isotonic shortening of skinned muscle fibers
PubMed: Stimuli-responsive polymer-doxorubicin conjugate: Antitumor mechanism and potential as nano-prodrug
PubMed: Direct extraction of G-actin from the myosin-removed myofibrils under the conditions of low ionic strength
PubMed: Mechanism of actomyosin adenosine triphosphatase. Evidence that adenosine 5'-triphosphate hydrolysis can occur without dissociation of the actomyosin complex
PubMed: Myosin V: Chemomechanical-coupling ratchet with load-induced mechanical slip
PubMed: The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma
PubMed: Cooperative actions between myosin heads bring effective functions
PubMed: Cloning and characterization of the ecto-nucleotidase NTPDase3 from rat brain: Predicted secondary structure and relation to other members of the E-NTPDase family and actin
PubMed: Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis
PubMed: The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay
PubMed: Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin
PubMed: Mechanism of ATP hydrolysis by polymeric actin
PubMed: The end of a polymerizing actin filament contains numerous ATP-subunit segments that are disconnected by ADP-subunits resulting from ATP hydrolysis
PubMed: Small nuclear RNA-protein complex anchors on the actin filaments in bovine lymphocyte nuclear matrix
PubMed: The enterotoxin of Bacteroides fragilis is a metalloprotease
PubMed: Interaction of actin with N-ethylmaleimide modified heavy meromyosin in the presence and absence of adenosine triphosphate
PubMed: Influence of the interaction between Ac?SDKP and Ang II on the pathogenesis and development of silicotic fibrosis
PubMed: Nonlinear dependence on actin of acto-heavy meromyosin 18O exchange and ATPase rate at low actin concentrations
PubMed: ATP-dependent fluctuations of single actin filaments in vitro
PubMed: Phosphatidylinositol 4-kinases and the role of polyphosphoinositides in cellular regulation
PubMed: Activation of Arp2/3 complex by Wiskott-Aldrich Syndrome protein is linked to enhanced binding of ATP to Arp2
PubMed: A genetic approach to detect muscle protein interactions in vivo
PubMed: Design and functional analysis of actomyosin motor domain chimera proteins
PubMed: On the mechanism of actin monomer-polymer subunit exchange at steady state
PubMed: Influence of phalloidin on ATP hydrolysis during actin polymerization
PubMed: Tropomyosin as a regulator of the sliding movement of actin filaments
PubMed: The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase
PubMed: Purification and characterization of myosin from calf brain
PubMed: Adenosine 5'-(gamma-thiotriphosphate): an ATP analog that should be used with caution in muscle contraction studies
PubMed: The purification and characterization of a globular subfragment of Acanthamoeba myosin II that is fully active when cross-linked to F-actin
PubMed: Elementary steps of the actin-activated ATPase reaction of cardiac muscle myosin subfragment-1
PubMed: Differential SKIP expression in PTEN-deficient glioblastoma regulates cellular proliferation and migration
PubMed: Gamma-amido-ATP stabilizes a high-fluorescence state of myosin subfragment 1
PubMed: Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin
PubMed: Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene
PubMed: Enzymatic characterization of arginine esterase from dog seminal plasma
PubMed: Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts
PubMed: Fragmentation of actin by thrombin-like snake venom proteases
PubMed: Glatiramer acetate and nanny proteins restrict access of the multiple sclerosis autoantigen myelin basic protein to the 26S proteasome
PubMed: Pollen tube tip growth depends on plasma membrane polarization mediated by tobacco PLC3 activity and endocytic membrane recycling
PubMed: HIV-1 protease cleaves actin during acute infection of human T-lymphocytes
PubMed: Upregulation of soluble epoxide hydrolase in proximal tubular cells mediated proteinuria-induced renal damage
PubMed: Enzymatic activities, activation by actin, and synthesis of cardiac atrial myosin: distinctive enzymatic properties compared with cardiac ventricular myosin
PubMed: Function of M-line-bound creatine kinase as intramyofibrillar ATP regenerator at the receiving end of the phosphorylcreatine shuttle in muscle
PubMed: The interaction and photolabeling of myosin subfragment 1 with 3'(2')-O-(4-benzoyl)benzoyladenosine 5'-triphosphate
PubMed: Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
PubMed: Cyclic Hydraulic Pressure and Fluid Flow Differentially Modulate Cytoskeleton Re-Organization in MC3T3 Osteoblasts
PubMed: Proteomic analysis of water soluble and myofibrillar protein changes occurring in dry-cured hams
PubMed: Influence of phallotoxins and metal ions on the rate of proteolysis of actin
PubMed: Interaction of myosin subfragment 1 with two non-nucleotide ATP analogues
PubMed: VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue
PubMed: Phosphoinositide-specific phospholipase C interacts with phosphatidylinositol kinase homolog TOR2
PubMed: Role of creatine in the regulation of cardiac protein synthesis
PubMed: Statistical properties of the dichotomous noise generated in biochemical processes
PubMed: Proteolytic fragments of connectin cause aggregation of myosin filaments but not of actin filaments
PubMed: A mutant heterodimeric myosin with one inactive head generates maximal displacement
PubMed: Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement
PubMed: Fibrillar microfilaments associated with a high-amylose rice, goami 2, a mutant of ilpumbyeo, a high-quality japonica rice
PubMed: Catalytic consequences of oligomeric organization: kinetic evidence for "tethered" acto-heavy meromyosin at low ATP concentrations
PubMed: Purification and characterization of heat-stable alkaline proteinase from bigeye snapper (Priacanthus macracanthus) muscle
PubMed: Stiffness and fraction of Myosin motors responsible for active force in permeabilized muscle fibers from rabbit psoas
PubMed: A thermodynamic muscle model and a chemical basis for A.V. Hill's muscle equation
PubMed: Oxygen exchange during the acto-subfragment-1 ATPase reaction: evidence for the two-route mechanism of the actomyosin ATPase reaction
PubMed: Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito
PubMed: ADP-ribosylarginine glycohydrolase catalyzing the release of ADP-ribose from the cholera toxin-modified alpha-subunits of GTP-binding proteins
PubMed: X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain
PubMed: Ultrastructure of the cell wall of Schizosaccharomyces pombe following treatment with various glucanases
PubMed: Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane
PubMed: Identification of the Jak/Stat proteins as novel downstream targets of EphA4 signaling in muscle: implications in the regulation of acetylcholinesterase expression
PubMed: Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins
PubMed: Gelsolin binding to phosphatidylinositol 4,5-bisphosphate is modulated by calcium and pH
PubMed: FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima--quantitation, GTP hydrolysis, and assembly
PubMed: Isolation of a sixth dynein subunit adenosine triphosphatase of Chlamydomonas axonemes
PubMed: Computational simulation of hypertrophic cardiomyopathy mutations in troponin I: influence of increased myofilament calcium sensitivity on isometric force, ATPase and [Ca2+]i
PubMed: Phospholipaise A2 and arachidonic acid-mediated mechanism of neuroexocytosis: a possible target of botidinum neurotoxin A other then SNAP-25
PubMed: Identification of a myofibril-bound serine proteinase (MBSP) in the skeletal muscle of lizard fish Saurida wanieso which specifically cleaves the arginine site
PubMed: Purification and characterization of myofibril-bound serine protease from lizard fish (Saurida undosquamis) muscle
PubMed: Protein-blotting on Polybrene-coated glass-fiber sheets. A basis for acid hydrolysis and gas-phase sequencing of picomole quantities of protein previously separated on sodium dodecyl sulfate/polyacr
PubMed: Texas Res-X and rhodamine Red-X, new derivatives of sulforhodamine 101 and lissamine rhodamine B with improved labeling and fluorescence properties
PubMed: Pioglitazone induces plasma platelet activating factor-acetylhydrolase and inhibits platelet activating factor-mediated cytoskeletal reorganization in macrophage
PubMed: Determination of 3-methylhistidine by capillary electrophoresis
PubMed: Comparative action of cathepsins D, B, H, L and of a new lysosomal cysteine proteinase on rabbit myofibrils
PubMed: Characterization of an alkaline proteinase of fish muscle
PubMed: Reaction of two heads of gizzard myosin with ATP
PubMed: Effects of surface adsorption on catalytic activity of heavy meromyosin studied using a fluorescent ATP analogue
PubMed: Purification and characterization of high Ca2+-requiring neutral proteases from porcine and bovine brains
PubMed: Cyclic peptides. VIII. Synthesis and tryptic hydrolysis of cyclic depsidipeptides containing a lysine residue
PubMed: Cell motility and thermodynamic fluctuations tailoring quantum mechanics for biology
PubMed: Orientation of spin-labeled nucleotides bound to myosin in glycerinated muscle fibers
PubMed: 2-[(4-Azido-2-nitrophenyl)amino]ethyl triphosphate, a novel chromophoric and photoaffinity analogue of ATP. Synthesis, characterization, and interaction with myosin subfragment 1
PubMed: Localization of the ATP-binding site in the 23-kDa and 20-kDa regions of the heavy chain of the skeletal muscle myosin head
PubMed: Structural changes induced in Ca2+-regulated myosin filaments by Ca2+ and ATP
PubMed: Mode of action of rabbit skeletal muscle cathepsin B towards myofibrillar proteins and the myofibrillar structure
PubMed: ATP dependence of NHE-1, the ubiquitous isoform of the Na+/H+ antiporter. Analysis of phosphorylation and subcellular localization
PubMed: Use of a commercial protease and yeasts to obtain CGRP-like molecules from saithe protein
PubMed: Effect of cerastobin, a thrombinlike enzyme from Cerastes vipera (Egyptian sand snake) venom, on human platelets
PubMed: Persistent activation of platelet membrane phospholipase C by proteolytic action of trypsin and thrombin
PubMed: Endotoxin stimulates lymphocyte glutaminase expression
PubMed: Human Tonic and Phasic Smooth Muscle Myosin Isoforms Are Unresponsive to the Loop 1 Insert
PubMed: Purification and characterization of cathepsin B from monkey skeletal muscle
PubMed: The internalist enterprise on constructing cell motility in a bottom-up manner
PubMed: The role of calpain in stimulus-response coupling: evidence that calpain mediates agonist-induced expression of procoagulant activity in platelets
PubMed: Interaction of myosin with thin filaments during contraction and relaxation: effect of ionic strength
PubMed: Mode of degradation of myofibrillar proteins by rabbit muscle cathepsin D
PubMed: Heterologous Expression of a Candida molischiana Anthocyanin-beta-glucosidase in a Wine Yeast Strain
PubMed: Ca2+-dependent proteolytic activity in crab claw muscle. Effects of inhibitors and specificity for myofibrillar proteins
PubMed: [Purification and some properties of skeletal muscle sarcolemma Ca2+-ATPase]
PubMed: Contractile proteins in epidermis. Isolation and properties of guinea-pig epidermal myosin
PubMed: Rotation of the c subunit oligomer in EF(0)EF(1) mutant cD61N
PubMed: Adenosine triphosphatases associated with bovine brain microtubules. II. Properties of ATPases I and II
PubMed: Interaction between actomyosin and 8-substituted ATP analogs
PubMed: A study on the reactions of tubercidin triphosphate with myosin and actomyosin
PubMed: Patterns of guanine nucleotide exchange reflecting disparate neutrophil activation pathways by opsonized and unopsonized Candida albicans hyphae
PubMed: Apparently irreversible GTP hydrolysis attends tubulin self-assembly
PubMed: Characterization of a pancreatic DNase from pyloric caeca of atlantic cod (Gadus morhua L.)
PubMed: Identification of two new calcium dependent hydrolases in the human heart
PubMed: Covalent binding of lipids to cytoskeletal proteins of mouse mammary epithelial cells
PubMed: [ECP 32 proteinase: characteristics of the enzyme, study of specificity]
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