arecoline hydrobromide
methyl N-methyl-1,2,5,6-tetrahydronicotinate hydrobromide
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
      Facebook
      Twitter
      Linkedin
      Blog
      Get the App!
      Product(s):
      300-08-3 Arecoline hydrobromide >98%
      Arecoline is a muscarinic acetylcholine receptor agonist.
       
       
  • Glentham Life Sciences
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
      Facebook
      Twitter
      Instagram
      Linkedin
      Product(s):
      A0523 Arecoline Hydrobromide >98.0%(HPLC)(T)
       
Synonyms   Articles   Notes   Search
CAS Number: 300-08-3Picture of molecule3D/inchi
FDA UNII: 24S79B9CX7
Beilstein Number: 3914826
MDL: MFCD00039041
Molecular Weight: 236.10898000
Formula: C8 H14 Br N O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 3.538e+005 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Arecoline hydrobromide 98%
BOC Sciences
For experimental / research use only.
Arecoline hydrobromide >98%
Odor: characteristic
Use: Arecoline is a muscarinic acetylcholine receptor agonist.
ExtraSynthese
For experimental / research use only.
Arecoline Hydrobromide
Glentham Life Sciences
Arecoline hydrobromide
Santa Cruz Biotechnology
For experimental / research use only.
Arecoline Hydrobromide ≥99%
Sigma-Aldrich
For experimental / research use only.
Arecoline Hydrobromide VETRANAL™
analytical standard
TCI AMERICA
For experimental / research use only.
Arecoline Hydrobromide >98.0%(HPLC)(T)
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
parenteral-frog LD50  160 mg/kg
Acta Biologica et Medica Germanica. Vol. 28, Pg. 681, 1972.

intravenous-mouse LD50  18 mg/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11778

oral-mouse LD50  600 mg/kg
United States Patent Document. Vol. #4921868

parenteral-rat LD50  270 mg/kg
Acta Biologica et Medica Germanica. Vol. 28, Pg. 681, 1972.

Dermal Toxicity:
subcutaneous-mouse LDLo 65 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 35, Pg. 75, 1929.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: pharmaceuticals / chemical synthisis
Recommendation for arecoline hydrobromide usage levels up to:
 not for fragrance use.
 
Recommendation for arecoline hydrobromide flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 9301
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide
Chemidplus: 0000300083
RTECS: QT2275000 for cas# 300-08-3
Synonyms   Articles   Notes   Search   Top
References:
 methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 9301
Pubchem (sid): 134975283
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
 arecoline bromide
 arekolinhydrobromid
 methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide
 methyl 1,2,5,6-tetrahydro-1-methylnicotinate, hydrobromide
 methyl N-methyl-1,2,5,6-tetrahydronicotinate hydrobromide
N-methyltetrahydronicotinic acid methyl ester hydrobromide
 nicotinic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide
3-pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide (9CI)
 taeniolin
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Determination and pharmacokinetic studies of arecoline in dog plasma by liquid chromatography-tandem mass spectrometry.
PubMed: Effects of arecoline on hepatic cytochrome P450 activity and oxidative stress.
PubMed: Assessment of the mutagenic potential of arecoline in gpt delta transgenic mice.
PubMed: Frequency- and state-dependent blockade of human ether-a-go-go-related gene K+ channel by arecoline hydrobromide.
PubMed: Surface plasmon resonance based biosensors for exploring the influence of alkaloids on aggregation of amyloid-β peptide.
PubMed: Association constants of pyridine and piperidine alkaloids to amyloid beta peptide determined by electrochemical impedance spectroscopy.
PubMed: Echinococcus granulosus and other intestinal helminths in semi-stray dogs in Tunisia: infection and re-infection rates.
PubMed: Screening for Echinococcus granulosus in dogs: Comparison between arecoline purgation, coproELISA and coproPCR with necropsy in pre-patent infections.
PubMed: Echinococcus granulosus in northern Queensland. 2. Ecological determinants of infection in beef cattle.
PubMed: Patent and pre-patent detection of Echinococcus granulosus genotypes in the definitive host.
PubMed: Combined use of tertiary amine parasympathomimetics with a quaternary amine parasympatholitic--a new perspective to use parasympathomimetic drugs for systemic analgesia.
PubMed: Hydatidosis in the province of La Pampa, Argentina, 1998.
PubMed: Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.
PubMed: [Echinococcosis/hydatidosis in the VII Region of Chile: diagnosis and educational intervention].
PubMed: Canine echinococcosis: an alternative for surveillance epidemiology.
PubMed: Teratogenicity of arecoline hydrobromide on developing chick embryos: a preliminary report.
PubMed: An epidemiological survey of Echinococcus granulosus and other helminths in animal populations in northern Israel.
PubMed: Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.
PubMed: Echinococcus granulosus infection of farm dogs of Iran.
PubMed: Echinococcus granulosus infections of dogs in the Durazno region of Uruguay.
PubMed: Histological preparation of the Echinococcus sp. tapeworms: staining affinity of the adult form.
PubMed: The cholinergic rapid eye movement induction test with arecoline in depression.
PubMed: Arecoline, but not haloperidol, induces changes in the permeability of the blood-brain barrier in the rat.
PubMed: Multiple-dose arecoline infusions in Alzheimer's disease.
PubMed: Memory retention test performance in mice: improvement by chronic oral cholinergic drug treatment.
PubMed: Autonomic function in cholinergic urticaria and atopic eczema.
PubMed: Memory retention: effect of prolonged cholinergic stimulation in mice.
PubMed: [Hydatidosis: epidemiological study in the eastern region of the province of Formosa].
PubMed: The toxicity and efficiency of arecoline hydrobromide in the Tasmanian hydatid control program.
PubMed: Activity of uredofos, niclosamide, bunamidine hydrochloride, and arecoline hydrobromide against Mesocestoides corti in experimentally infected dogs.
PubMed: Prevalence of Echinococcus granulosus and other cestodes in dogs on the Navajo reservation in Arizona and New Mexico.
PubMed: Effect of deworming medication on the microbial flora of the upper gastrointestinal tract of dogs.
PubMed: Areca nut: a review.
PubMed: Comparative value of arecoline hydrobromide and bunamidine hydrochloride for the treatment of Echinococcus granulosus in dogs.
PubMed: [A guide to the use of arecoline hydrobromide for the diagnosis of echinococcus granulosus infection in the dog (author's transl)].
PubMed: Surveillance of Echinococcus granulosus in dogs with arecoline hydrobromide.
PubMed: The Styx field-trial. A study on the application of control measures against hydatid disease caused by Echinococcus granulosus.
PubMed: Evaluation of selected drugs for the treatment of canine echinococcosis.
PubMed: THE RELATION BETWEEN METHOD OF ADMINISTRATION, ROUTE OF ABSORPTION, INHIBITORY ACTIONS AND ACUTE TOXICITY OF ARECOLINE HYDROBROMIDE IN DOGS.
PubMed: THE USE OF ARECOLINE HYDROBROMIDE IN THE TREATMENT OF TAENIID INFECTIONS IN DOGS.
PubMed: Effect of combined arecoline hydrobromide and n-butyl chloride complex on parasites of dogs.
PubMed: [Dehelmintization of geese with arecoline hydrobromide].
PubMed: [Effect of vitamin B1 on arecoline hydrobromide in dye shock].
PubMed: [Effect of arecoline hydrobromide on the peripheral blood vessels in rabbits].
PubMed: Testing arecoline hydrobromide as an anthelminthic for hydatid worms in dogs.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2021 Perflavory ™ Disclaimer Privacy Policy