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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 408.90 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 317.00 °F. TCC ( 158.20 °C. ) (est)
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| logP (o/w): | 0.220 (est) |
| Soluble in: |
| | water, 9.105e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for elenolic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for elenolic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 169607 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | 2-[(2S,3S,4S)-3-formyl-5-methoxycarbonyl-2-methyl-3,4-dihydro-2H-pyran-4-yl]acetic acid |
| Chemidplus: | 0034422123 |
References:
| | 2-[(2S,3S,4S)-3-formyl-5-methoxycarbonyl-2-methyl-3,4-dihydro-2H-pyran-4-yl]acetic acid |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 169607 |
| Pubchem (sid): | 135126592 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 3- | formyl-3,4-dihydro-5-(methoxycarbonyl)-2-methyl-2H-pyran-4-acetic acid | | [(2S,3S,4S)-3- | formyl-5-(methoxycarbonyl)-2-methyl-3,4-dihydro-2H-pyran-4-yl]acetic acid | | 2-[(2S,3S,4S)-3- | formyl-5-methoxycarbonyl-2-methyl-3,4-dihydro-2H-pyran-4-yl]acetic acid | | | glutaric acid, 3-(1-formylpropenyl)-2-(hydroxymethylene)-, 1-methyl ester | | 2H- | pyran-4-acetic acid, 3-formyl-3,4-dihydro-5-(methoxycarbonyl)-2-methyl-, (2S-(2alpha,3alpha,4beta))- |
Articles:
| PubMed: | Oleacein. Translation from Mediterranean Diet to Potential Antiatherosclerotic Drug. |
| PubMed: | Recovering bioactive compounds from olive oil filter cake by advanced extraction techniques. |
| PubMed: | Use of dried stoned olive pomace in the feeding of lactating buffaloes: effect on the quantity and quality of the milk produced. |
| PubMed: | Secoiridoid type of antiallergic substances in olive waste materials of three Japanese varieties of Olea europaea. |
| PubMed: | Inhibition of human neutrophils NEP activity, CD11b/CD18 expression and elastase release by 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde, oleacein. |
| PubMed: | Looking beyond sugars: phytochemical profiling and standardization of manna exudates from Sicilian Fraxinus excelsior L. |
| PubMed: | Insight into virgin olive oil secoiridoids characterization by high-resolution mass spectrometry and accurate mass measurements. |
| PubMed: | Effect of olive oil phenols on the production of inflammatory mediators in freshly isolated human monocytes. |
| PubMed: | Characterization of 3,4-DHPEA-EDA oxidation products in virgin olive oil by high performance liquid chromatography coupled with mass spectrometry. |
| PubMed: | Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer. |
| PubMed: | High-performance liquid chromatography-mass spectrometry profiling of phenolic compounds for evaluation of olive oil bitterness and pungency. |
| PubMed: | Phenolic composition, isolation, and structure of a new deoxyloganic acid derivative from Dhokar and Gemri-Dhokar olive cultivars. |
| PubMed: | Absorption and metabolism of olive oil secoiridoids in the small intestine. |
| PubMed: | Chemical and cellular antioxidant activity of phytochemicals purified from olive mill waste waters. |
| PubMed: | Characterization of antioxidant olive oil biophenols by spectroscopic methods. |
| PubMed: | Cardioprotective and neuroprotective roles of oleuropein in olive. |
| PubMed: | Effects of heating on virgin olive oils and their blends: focus on modifications of phenolic fraction. |
| PubMed: | Effects of olive maturation and stoning on quality indices and antioxidant content of extra virgin oils (cv. Coratina) during storage. |
| PubMed: | Effect of olive ripeness on chemical properties and phenolic composition of Chétoui virgin olive oil. |
| PubMed: | Qualitative screening of phenolic compounds in olive leaf extracts by hyphenated liquid chromatography and preliminary evaluation of cytotoxic activity against human breast cancer cells. |
| PubMed: | Bactericidal activity of glutaraldehyde-like compounds from olive products. |
| PubMed: | Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-induced hemolysis. |
| PubMed: | Simultaneous quantification of oleuropein and its metabolites in rat plasma by liquid chromatography electrospray ionization tandem mass spectrometry. |
| PubMed: | Effect of irrigation on quality attributes of olive oil. |
| PubMed: | Effects of olive oil polyphenols on erythrocyte oxidative damage. |
| PubMed: | Effect of malaxation conditions on phenol and volatile profiles in olive paste and the corresponding virgin olive oils (Olea europaea L. Cv. Cornicabra). |
| PubMed: | Chemistry and bioactivity of olive biophenols in some antioxidant and antiproliferative in vitro bioassays. |
| PubMed: | tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO). |
| PubMed: | Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2. |
| PubMed: | Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays. |
| PubMed: | Main antimicrobial compounds in table olives. |
| PubMed: | Chemical screening of olive biophenol extracts by hyphenated liquid chromatography. |
| PubMed: | Effect of olive stoning on the volatile and phenolic composition of virgin olive oil. |
| PubMed: | Irrigation effects on quality, phenolic composition, and selected volatiles of virgin olive oils cv. Leccino. |
| PubMed: | Computational study of bindings of olive leaf extract (OLE) to HIV-1 fusion protein gp41. |
| PubMed: | Evaluation of the influence of thermal oxidation on the phenolic composition and on the antioxidant activity of extra-virgin olive oils. |
| PubMed: | Changes in volatile and phenolic compounds with malaxation time and temperature during virgin olive oil production. |
| PubMed: | Capillary electrophoresis-electrospray ionization-mass spectrometry method to determine the phenolic fraction of extra-virgin olive oil. |
| PubMed: | Effects of copper on the antioxidant activity of olive polyphenols in bulk oil and oil-in-water emulsions. |
| PubMed: | Evaluation of phenolic compounds in virgin olive oil by direct injection in high-performance liquid chromatography with fluorometric detection. |
| PubMed: | Solid-phase extraction gas chromatography-ion trap-mass spectrometry qualitative method for evaluation of phenolic compounds in virgin olive oil and structural confirmation of oleuropein and ligstroside aglycons and their oxidation products. |
| PubMed: | Electrophoretic identification and quantitation of compounds in the polyphenolic fraction of extra-virgin olive oil. |
| PubMed: | Development of a sensitive and specific solid phase extraction--gas chromatography-tandem mass spectrometry method for the determination of elenolic acid, hydroxytyrosol, and tyrosol in rat urine. |
| PubMed: | Interactions of ferric ions with olive oil phenolic compounds. |
| PubMed: | Antioxidant activity of olive pulp and olive oil phenolic compounds of the arbequina cultivar. |
| PubMed: | Polyphenol changes during fermentation of naturally black olives. |
| PubMed: | Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. |
| PubMed: | Changes in phenolic composition and antioxidant activity of virgin olive oil during frying. |
| PubMed: | Comparison of the antioxidant activities of extra virgin olive oils. |
| PubMed: | Phenolic compounds profile of cornicabra virgin olive oil. |
| PubMed: | Deterioration of natural antioxidant species of vegetable edible oils during the domestic deep-frying and pan-frying of potatoes. |
| PubMed: | Partition behavior of virgin olive oil phenolic compounds in oil-brine mixtures during thermal processing for fish canning. |
| PubMed: | Partitioning of olive oil antioxidants between oil and water phases. |
| PubMed: | Changes in the phenolic composition of virgin olive oil from young trees (Olea europaea L. cv. Arbequina) grown under linear irrigation strategies. |
| PubMed: | Antioxidant activity of the main bioactive derivatives from oleuropein hydrolysis by hyperthermophilic beta-glycosidase. |
| PubMed: | Effect of enzyme treatment during mechanical extraction of olive oil on phenolic compounds and polysaccharides. |
| PubMed: | Phenolic Compounds in Different Olive Varieties. |
| PubMed: | Rapid evaluation of phenolic component profile and analysis of oleuropein aglycon in olive oil by atmospheric pressure chemical ionization-mass spectrometry (APCI-MS). |
| PubMed: | Hydrolysis of oleuropein by recombinant beta-glycosidase from hyperthermophilic archaeon Sulfolobus solfataricus immobilised on chitosan matrix. |
| PubMed: | Phenolic compounds in Spanish olive oils. |
| PubMed: | Antioxidant activity of 3,4-DHPEA-EA and protocatechuic acid: a comparative assessment with other olive oil biophenols. |
| PubMed: | [Occlusion by adhesions treated by celioscopic section]. |
| PubMed: | Antimicrobial properties of oleuropein and products of its hydrolysis from green olives. |
| PubMed: | Preparation of antimicrobial compounds by hydrolysis of oleuropein from green olives. |
| PubMed: | Structure and stereochemistry of elenolic acid. |
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