eriocitrin
glucopyranoside, eriodictyol-7 6-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D-
 
Notes:
Isol. from Mentha piperita (peppermint) leaves and from Citrus spp. Eriocitrin is a flavonoid glycoside that can be found in plants like Citrus grandis, Citrus limon, Mentha longifolia, Mentha piperita, Thymus vulgaris. It shows important antioxidant activities.
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      Product(s):
      13463-28-0 Eriocitrin >98%
      Eriocitrin is a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. It might play an important role in the control of the change in glutathione redox status in rat liver during exercise.
       
       
Synonyms   Articles   Notes   Search
CAS Number: 13463-28-0Picture of molecule3D/inchi
Other(deleted CASRN): 32737-63-6
ECHA EINECS - REACH Pre-Reg: 236-668-7
FDA UNII: AS293HR5XQ
Nikkaji Web: J317.894C
Beilstein Number: 1304401
MDL: MFCD00017472
XlogP3-AA: -1.40 (est)
Molecular Weight: 596.54004000
Formula: C27 H32 O15
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 956.90 °C. @ 760.00 mm Hg (est)
Flash Point: 603.00 °F. TCC ( 317.00 °C. ) (est)
logP (o/w): 1.470 (est)
Soluble in:
 water, 4787 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Alfa Biotechnology
For experimental / research use only.
Eriocitrin; Eriodictioside; Eriodictyol 7-O-rutinoside 98%
BOC Sciences
For experimental / research use only.
Eriocitrin >98%
Odor: characteristic
Use: Eriocitrin is a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. It might play an important role in the control of the change in glutathione redox status in rat liver during exercise.
Carbosynth
For experimental / research use only.
Eriocitrin
ExtraSynthese
For experimental / research use only.
Eriocitrin (HPLC) ≥98%
Santa Cruz Biotechnology
For experimental / research use only.
Eriocitrin ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
Eriocitrin ≥98.0% (HPLC)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for eriocitrin usage levels up to:
 not for fragrance use.
 
Recommendation for eriocitrin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 83489
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochrom
Chemidplus: 0013463280
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References:
 (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochrom
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 13463-28-0
Pubchem (cid): 83489
Pubchem (sid): 135041897
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C09732
HMDB (The Human Metabolome Database): HMDB05811
FooDB: FDB016547
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 horsemint plant
Search Trop  Picture
 lemon fruit
Search Trop  Picture
 lemon leaf
Search Trop  Picture
 lemon pericarp
Search Trop  Picture
 mint wild mint
Search Trop  Picture
 orange flower
Search Trop  Picture
 orange pericarp
Search Trop  Picture
 peppermint leaf
Search Trop  Picture
 pomegranate leaf
Search Trop  Picture
 pomelo
Search Trop  Picture
 savory winter savory plant
Search Trop  Picture
 thyme
Search Trop  Picture
 water mint plant
Search Trop  Picture
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Synonyms:
4H-1-benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-, (S)-
(S)-7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-one
(2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochrom
 eriodictioside
 eriodictyol-7-O-rutinoside
 flavanone, 3',4',5,7-tetrahydroxy-, 7-(6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside)
 glucopyranoside, eriodictyol-7 6-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D-
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Articles:
PubMed: Chemopreventive potential of phenolic compounds in oral carcinogenesis.
PubMed: Sonochemical effects on 14 flavonoids common in citrus: relation to stability.
PubMed: Thorough investigation of the oxygen heterocyclic fraction of lime (Citrus aurantifolia (Christm.) Swingle) juice.
PubMed: Feijoa sellowiana Berg fruit juice: anti-inflammatory effect and activity on superoxide anion generation.
PubMed: Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis.
PubMed: Hexanoyl-lysine as an oxidative-injured marker - application of development of functional food.
PubMed: [Analysis on component difference in Citrus reticulata before and after being processed with salt by UPLC-Q-TOF/MS].
PubMed: Simplified miniaturized ultrasound-assisted matrix solid phase dispersion extraction and high performance liquid chromatographic determination of seven flavonoids in citrus fruit juice and human fluid samples: hesperetin and naringenin as biomarkers.
PubMed: Food ingredient extracts of Cyclopia subternata (Honeybush): variation in phenolic composition and antioxidant capacity.
PubMed: In vitro antiallergic effects of aqueous fermented preparations from Citrus and Cydonia fruits.
PubMed: Protective effect of Calamintha officinalis Moench leaves against alcohol-induced gastric mucosa injury in rats. Macroscopic, histologic and phytochemical analysis.
PubMed: HPLC determination of hesperidin, diosmin and eriocitrin in Iranian lime juice using polyamide as an adsorbent for solid phase extraction.
PubMed: UV-B modulates the interplay between terpenoids and flavonoids in peppermint (Mentha x piperita L.).
PubMed: Effect of pre-drying treatments and storage on color and phenolic composition of green honeybush (Cyclopia subternata) herbal tea.
PubMed: In vitro cultures of Cyclopia plants (honeybush) as a source of bioactive xanthones and flavanones.
PubMed: Phenolic profile and antioxidant evaluation of Mentha x piperita L. (peppermint) extracts.
PubMed: Phenolic contribution of South African herbal teas to a healthy diet.
PubMed: Determination of water-soluble polyphenolic compounds in commercial herbal teas from Lamiaceae: peppermint, melissa, and sage.
PubMed: Isolation of antioxidative phenolic glucosides from lemon juice and their suppressive effect on the expression of blood adhesion molecules.
PubMed: The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.) and wild thyme (Thymus serpyllum L.) on the copper-induced oxidation of human low-density lipoproteins.
PubMed: Racemization at C-2 of naringin in sour oranges with increasing maturity determined by chiral high-performance liquid chromatography.
PubMed: Determination of phenolic compounds in fennel by HPLC and HPLC-MS using a monolithic reversed-phase column.
PubMed: A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.).
PubMed: Difference in plasma metabolite concentration after ingestion of lemon flavonoids and their aglycones in humans.
PubMed: Antiradical and anti-H2O2 properties of polyphenolic compounds from an aqueous peppermint extract.
PubMed: Analysis of flavanone-7-O-glycosides in citrus juices by short-end capillary electrochromatography.
PubMed: Phenolic metabolites from honeybush tea (Cyclopia subternata).
PubMed: Separation of flavanone-7-O-glycoside diastereomers and analysis in citrus juices by multidimensional liquid chromatography coupled with mass spectrometry.
PubMed: Screening of free radical scavenging compounds in water extracts of Mentha samples using a postcolumn derivatization method.
PubMed: Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. postulation of a biosynthetic pathway.
PubMed: Effect of the rootstock and interstock grafted in lemon tree (Citrus limon (L.) Burm.) on the flavonoid content of lemon juice.
PubMed: Flavonoids detection by HPLC-DAD-MS-MS in lemon juices from Sicilian cultivars.
PubMed: Lemon flavonoid, eriocitrin, suppresses exercise-induced oxidative damage in rat liver.
PubMed: Antiallergic effect of flavonoid glycosides obtained from Mentha piperita L.
PubMed: Chiral separation of six diastereomeric flavanone-7-O-glycosides by capillary electrophoresis and analysis of lemon juice.
PubMed: Identification and antioxidant activity of flavonoid metabolites in plasma and urine of eriocitrin-treated rats.
PubMed: Preparation of a monoclonal antibody to N(epsilon)-(Hexanonyl)lysine: application to the evaluation of protective effects of flavonoid supplementation against exercise-induced oxidative stress in rat skeletal muscle.
PubMed: Apoptosis induced by the flavonoid from lemon fruit (Citrus limon BURM. f.) and its metabolites in HL-60 cells.
PubMed: Validation of a liquid chromatography ionspray mass spectrometry method for the analysis of flavanones, flavones and flavonols.
PubMed: [Standardization of the sour orange flower and leaf].
PubMed: Protective effects of lemon flavonoids on oxidative stress in diabetic rats.
PubMed: [Aromatic and polyphenolic composition of infused peppermint, Mentha x piperita L].
PubMed: Colorimetric determination of eriodictyol and its glycoside, eriocitrin.
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