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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 921.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 951.00 °F. TCC ( 510.80 °C. ) (est)
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| logP (o/w): | 3.560 (est) |
| Soluble in: |
| | water, 0.1125 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 1340 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 539, 1975.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for ginsenoside Rf usage levels up to: | | | not for fragrance use.
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| Recommendation for ginsenoside Rf flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | ginsenoside RF | | | panaxoside Rf | | | panaxoside RF |
Articles:
| PubMed: | Discrimination of white ginseng origins using multivariate statistical analysis of data sets. |
| PubMed: | Detoxifying effect of fermented black ginseng on H2O2-induced oxidative stress in HepG2 cells. |
| PubMed: | [Determination of twelve active compounds in Qili Qiangxin capsules by UPLC-MS]. |
| PubMed: | Metabolomic approach for discrimination of processed ginseng genus (Panax ginseng and Panax quinquefolius) using UPLC-QTOF MS. |
| PubMed: | Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters. |
| PubMed: | [Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province]. |
| PubMed: | Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG‑63 cells through the mitochondrial pathway. |
| PubMed: | Production of aglycone protopanaxatriol from ginseng root extract using Dictyoglomus turgidum β-glycosidase that specifically hydrolyzes the xylose at the C-6 position and the glucose in protopanaxatriol-type ginsenosides. |
| PubMed: | Updating chemical profiling of red ginseng via the elucidation of two geometric isomers of ginsenosides Rg9 and Rg10. |
| PubMed: | Ginsenjilinol, a new protopanaxatriol-type saponin with inhibitory activity on LPS-activated NO production in macrophage RAW 264.7 cells from the roots and rhizomes of Panax ginseng. |
| PubMed: | Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice. |
| PubMed: | Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways. |
| PubMed: | Mass spectrometric imaging of ginsenosides localization in Panax ginseng root. |
| PubMed: | Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS. |
| PubMed: | Microbial conversion of rare ginsenoside Rf to 20(S)-protopanaxatriol by Aspergillus niger. |
| PubMed: | On-line concentration of neutral analytes by complexation and acetonitrile sweeping in nonionic microemulsion electrokinetic chromatography with direct ultraviolet detection. |
| PubMed: | Biotransformation of ginsenoside Rf to Rh1 by recombinant beta-glucosidase. |
| PubMed: | Direct on-line analysis of neutral analytes by dual sweeping via complexation and organic solvent field enhancement in nonionic MEKC. |
| PubMed: | [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng]. |
| PubMed: | Pressure and electrokinetic injections for on-line sample stacking neutral analytes in microemulsion electrokinetic chromatography with salt-containing matrixes. |
| PubMed: | Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research. |
| PubMed: | Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons. |
| PubMed: | Retention behavior of ginsenosides on a poly(vinyl alcohol)-bonded stationary phase in hydrophilic interaction chromatography. |
| PubMed: | Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models. |
| PubMed: | Ginsenoside Rf, a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha. |
| PubMed: | Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes. |
| PubMed: | [Study on the chemical constituents of the roots of commercial ginseng]. |
| PubMed: | Phytochemistry of wild populations of Panax quinquefolius L. (North American ginseng). |
| PubMed: | Effects of ginsenosides on glycine receptor alpha1 channels expressed in Xenopus oocytes. |
| PubMed: | [Practical optimization of the two-dimensional thin-layer chromatographic separation of ginsenosides]. |
| PubMed: | Ginsenoside Rf potentiates U-50,488H-induced analgesia and inhibits tolerance to its analgesia in mice. |
| PubMed: | Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes. |
| PubMed: | The antimetastatic and immunomodulating activities of ginseng minor glycosides. |
| PubMed: | Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions. |
| PubMed: | Use of high-performance liquid chromatography-tandem mass spectrometry to distinguish Panax ginseng C. A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng). |
| PubMed: | Preparation of monoclonal antibody against ginsenoside Rf and its enzyme immunoassay. |
| PubMed: | Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS. |
| PubMed: | Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity. |
| PubMed: | Ginsenoside Rf2, a new dammarane glycoside from Korean red ginseng (Panax ginseng). |
| PubMed: | Determination of ginsenoside Rf and Rg2 from Panax ginseng using enzyme immunoassay. |
| PubMed: | Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice. |
| PubMed: | A trace component of ginseng that inhibits Ca2+ channels through a pertussis toxin-sensitive G protein. |
| PubMed: | Saponins from Vietnamese Ginseng, Panax vietnamensis HA et Grushv. Collected in central Vietnam. II. |
| PubMed: | [Suppression of lipid peroxidation by sho-saiko-to and its components in rat liver subcellular membranes]. |
| PubMed: | [Isolation and identification of saponin IV, V, VI and VII in ginseng stems]. |
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