Articles:
| PubMed: | Non-competitive androgen receptor inhibition in vitro and in vivo. |
7H-pyrido[3,4-b]indol-7-one, 2,9-dihydro-1-methyl-, hydrochloride (1:1)
Notes:
None found
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 40580-83-4 Harmol HCl > 95% Harmol HCl induces apoptosis by Caspase-8 activation.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GP8204 Harmol hydrochloride hydrate
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| CAS Number: | 40580-83-4 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 254-980-1 | |
| FDA UNII: | 7E16Y4FM83 | |
| MDL: | MFCD00150057 | |
| Molecular Weight: | 234.68487000 | |
| Formula: | C12 H11 Cl N2 O | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| Soluble in: | |
| water, 13.02 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Harmol HCl > 95%
Odor: characteristic Use: Harmol HCl induces apoptosis by Caspase-8 activation. |
| ExtraSynthese |
| For experimental / research use only. |
| Harmol Hydrochloride (HPLC) ≥95% |
| Glentham Life Sciences |
| Harmol hydrochloride hydrate |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Harmol Hydrochloride |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LDLo 140 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 4, Pg. 33, 1931. | |
| Dermal Toxicity: | |
|
subcutaneous-frog LDLo 180 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: ATAXIA CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION Quarterly Journal of Pharmacy & Pharmacology. Vol. 4, Pg. 33, 1931. subcutaneous-guinea pig LDLo 280 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 4, Pg. 33, 1931. subcutaneous-rabbit LDLo 400 mg/kg CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP BEHAVIORAL: FOOD INTAKE (ANIMAL) CARDIAC: PULSE RATE Quarterly Journal of Pharmacy & Pharmacology. Vol. 4, Pg. 33, 1931. subcutaneous-rat LDLo 400 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 4, Pg. 33, 1931. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis | ||
| Recommendation for harmol hydrochloride usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for harmol hydrochloride flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 94507 |
| National Institute of Allergy and Infectious Diseases: | Data |
| 1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one;hydrochloride | |
| Chemidplus: | 0040580834 |
| RTECS: | UV1048000 for cas# 40580-83-4 |
References:
| 1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one;hydrochloride | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 94507 |
| Pubchem (sid): | 135052100 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| harmol HCl | |
| 1- | methyl-beta-carbolin-7-ol hydrochloride monohydrate |
| 9H- | pyrido(3,4-b)indol-7-ol, 1-methyl-, hydrochloride |
| 7H- | pyrido[3,4-b]indol-7-one, 2,9-dihydro-1-methyl-, hydrochloride (1:1) |