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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 583.80 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 432.00 °F. TCC ( 222.10 °C. ) (est)
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| logP (o/w): | 2.900 (est) |
| Soluble in: |
| | water, 375 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for homoeriodictyol usage levels up to: | | | not for fragrance use.
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| Recommendation for homoeriodictyol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 3512637 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one |
References:
| | 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 3512637 |
| Pubchem (sid): | 37556616 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4H-1- | benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)- | | 5,7- | dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one | | 5,7- | dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one | | 4',5,7- | trihydroxy-3'-methoxyflavanone |
Articles:
| PubMed: | Cytotoxic and Anti-metastatic Activities of Phenolic Compounds from Dendrobium ellipsophyllum. |
| PubMed: | UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries. |
| PubMed: | Biosynthesis of homoeriodictyol from eriodictyol by flavone 3'-O-methyltransferase from recombinant Yarrowia lioplytica: Heterologous expression, biochemical characterization, and optimal transformation. |
| PubMed: | Physical activity increases the bioavailability of flavanones after dietary aronia-citrus juice intake in triathletes. |
| PubMed: | Identification of enterodiol as a masker for caffeine bitterness by using a pharmacophore model based on structural analogues of homoeriodictyol. |
| PubMed: | Optimizing the orosensory properties of model functional beverages: the influence of novel sweeteners, odorants, bitter blockers, and their mixtures on (+)-catechin. |
| PubMed: | [Study on the chemical constituents from Fructus Toosendan (III)]. |
| PubMed: | Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes. |
| PubMed: | Simultaneous determination of ten flavonoids from Viscum coloratum grown on different host species and different sources by LC-MS. |
| PubMed: | Flavanone glycosides from viscum coloratum and their inhibitory effects on osteoclast formation. |
| PubMed: | Isolation and identification of flavonoids accumulated in proanthocyanidin-free barley. |
| PubMed: | [Studies on the chemical constituents from the leave of Paulownia tomentosa]. |
| PubMed: | Stereospecific pharmacokinetics of racemic homoeriodictyol, isosakuranetin, and taxifolin in rats and their disposition in fruit. |
| PubMed: | Stereoisomeric separation of some flavanones using highly succinate-substituted α-cyclosophoro-octadecaoses as chiral additives in capillary electrophoresis. |
| PubMed: | [Studies on the flavonoids from Lignum Dalbergiae Odoriferae (II)]. |
| PubMed: | Identification of bisprenylated benzoic acid derivatives from yerba santa (Eriodictyon ssp.) using sensory-guided fractionation. |
| PubMed: | Characterization of flavor modulating effects in complex mixtures via high temperature liquid chromatography. |
| PubMed: | Flavonoids from Bauhinia glauca subsp. pernervosa. |
| PubMed: | [Flavones from flowers of Paulownia fortunei]. |
| PubMed: | Enantiomeric separation of some flavanones using shinorhizobial linear octasaccharides in CE. |
| PubMed: | Structural analogues of homoeriodictyol as flavor modifiers. Part III: short chain gingerdione derivatives. |
| PubMed: | Inhibitory activity of the ethyl acetate fraction from Viscum coloratum on bone resorption. |
| PubMed: | Stereospecific high-performance liquid chromatographic validation of homoeriodictyol in serum and Yerba Santa (Eriodictyon glutinosum). |
| PubMed: | HPLC determination and pharmacokinetic study of homoeriodictyol-7-O-beta-D-glucopyranoside in rat plasma and tissues. |
| PubMed: | Simultaneous determination of homoeriodictyol-7-O-beta-D-Glccopyranoside and its metabolite homoeriodictyol in rat tissues and urine by liquid chromatography-mass spectrometry. |
| PubMed: | Enantioseparation of some chiral flavanones using microbial cyclic beta-(1-->3),(1-->6)-glucans as novel chiral additives in capillary electrophoresis. |
| PubMed: | [Isolation and determination of homoeriodictyol-7-O-beta-D-glycoside in Viscum coloratum]. |
| PubMed: | New bitter-masking compounds: hydroxylated benzoic acid amides of aromatic amines as structural analogues of homoeriodictyol. |
| PubMed: | [Chemical constituents from Viscum nudum and their accelerating PC12 cell differentiation]. |
| PubMed: | Stereoisomeric separation of flavanones and flavanone-7-O-glycosides by capillary electrophoresis and determination of interconversion barriers. |
| PubMed: | Difference in plasma metabolite concentration after ingestion of lemon flavonoids and their aglycones in humans. |
| PubMed: | Antioxidative flavanone glycosides from the branches and leaves of Viscum coloratum. |
| PubMed: | Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae). |
| PubMed: | Identification and quantification of the conjugated metabolites derived from orally administered hesperidin in rat plasma. |
| PubMed: | Flavonoid methylation: a novel 4'-O-methyltransferase from Catharanthus roseus, and evidence that partially methylated flavanones are substrates of four different flavonoid dioxygenases. |
| PubMed: | Effect of the rootstock and interstock grafted in lemon tree (Citrus limon (L.) Burm.) on the flavonoid content of lemon juice. |
| PubMed: | Separation of some chiral flavanones by micellar electrokinetic chromatography. |
| PubMed: | O-demethylation and sulfation of 7-methoxylated flavanones by Cunninghamella elegans. |
| PubMed: | [Studies on the chemical constituents of Viscum coloratum]. |
| PubMed: | Phenolic glycosides from Viscum angulatum. |
| PubMed: | Identification and antioxidant activity of flavonoid metabolites in plasma and urine of eriocitrin-treated rats. |
| PubMed: | A study of the trypanocidal and analgesic properties from Lychnophora granmongolense (Duarte) Semir & Leitão Filho. |
| PubMed: | Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. |
| PubMed: | A chalcone synthase with an unusual substrate preference is expressed in barley leaves in response to UV light and pathogen attack. |
| PubMed: | Isolation of potential cancer chemopreventive agents from Eriodictyon californicum. |
| PubMed: | Pigment synthesis in maize aleurone from precursors fed to anthocyanin mutants. |
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