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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 572.10 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 423.00 °F. TCC ( 217.30 °C. ) (est)
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| logP (o/w): | 1.020 (est) |
| Soluble in: |
| | water, 1.05e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for methyl umbelliferyl-beta-D-xyloside usage levels up to: | | | not for fragrance use.
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| Recommendation for methyl umbelliferyl-beta-D-xyloside flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 4-methyl-7-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxychromen-2-one |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 92229 |
| Pubchem (sid): | 135047797 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2H-1- | benzopyran-2-one, 4-methyl-7-(beta-D-xylopyranosyloxy)- | | 4- | methyl-7-(beta-D-xylopyranosyloxy)-2H-1-benzopyran-2-one | | 4- | methyl-7-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxychromen-2-one | | 4- | methylumbelliferyl beta-xyloside | | | methylumbelliferyl-beta-D-xyloside |
Articles:
| PubMed: | Regulation of heparan sulfate and chondroitin sulfate glycosaminoglycan biosynthesis by 4-fluoro-glucosamine in murine airway smooth muscle cells. |
| PubMed: | A novel efflux-recapture process underlies the mechanism of high-density lipoprotein cholesteryl ester-selective uptake mediated by the low-density lipoprotein receptor-related protein. |
| PubMed: | Effects of [3H]glucosamine concentration on [3H]chondroitin sulphate formation by cultured chondrocytes. |
| PubMed: | HNK-1-Reactive oligosaccharide, sulfate-O-3GlcAbeta1-4Xylbeta1-MU, synthesized by cultured human colorectal cancer cells. |
| PubMed: | A sulfated proteoglycan is necessary for storage of exocrine secretory proteins in the rat parotid gland. |
| PubMed: | Obligatory requirement of sulfation for P-selectin binding to human salivary gland carcinoma Acc-M cells and breast carcinoma ZR-75-30 cells. |
| PubMed: | Effects of ATP on regulation of galactosyltransferase-I activity responsible for synthesis of the linkage region between the core protein and glycosaminoglycan chains of proteoglycans. |
| PubMed: | Mechanistic studies of active site mutants of Thermomonospora fusca endocellulase E2. |
| PubMed: | Enhanced channelling of sulphate through a rapidly exchangeable sulphate pool in response to stimulated glycosaminoglycan synthesis in pancreatic epithelial cells. |
| PubMed: | Alterations of matrix- and cell-associated proteoglycans inhibit osteogenesis and growth response to fibroblast growth factor-2 in cultured rat mandibular condyle and calvaria. |
| PubMed: | ApoE of the HepG2 cell surface includes a major pool associated with chondroitin sulfate proteoglycans. |
| PubMed: | Characterization of beta-D-xyloside-initiated glycosaminoglycan synthesized by human skin fibroblasts in the presence of tunicamycin. |
| PubMed: | A novel 4-methylumbelliferyl-beta-D-xyloside derivative, sulfate-O-3-xylosylbeta1-(4-methylumbelliferone), isolated from culture medium of human skin fibroblasts, and its role in methylumbelliferone-initiated glycosaminoglycan biosynthesis. |
| PubMed: | Effects of O-glycosylation inhibitors on the differentiation of HL-60 cells. |
| PubMed: | Effect of monensin on the synthesis of beta-D-xyloside-initiated glycosaminoglycan and its linkage region oligosaccharides in human skin fibroblasts. |
| PubMed: | Uptake of hypertriglyceridemic very low density lipoproteins and their remnants by HepG2 cells: the role of lipoprotein lipase, hepatic triglyceride lipase, and cell surface proteoglycans. |
| PubMed: | Lipoprotein lipase reduces secretion of apolipoprotein E from macrophages. |
| PubMed: | Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth. |
| PubMed: | Cell surface proteoglycans modulate net synthesis and secretion of macrophage apolipoprotein E. |
| PubMed: | Characterization and biological significance of sialyl alpha 2-3galactosyl beta 1-4xylosyl beta 1-(4-methylumbelliferone) synthesized in cultured human skin fibroblasts. |
| PubMed: | Inhibitory effect of platelet factor 4 on human erythroleukemic cells is dependent on cell surface heparan sulfate. |
| PubMed: | A new approach to mapping co-localization of multiple glycosyl transferases in functional Golgi preparations. |
| PubMed: | Reduction of intimal hyperplasia by naroparcil, a 4-methylumbelliferyl beta-D-xyloside analogue, after arterial injury in the hypercholesterolemic rabbit. |
| PubMed: | Inhibition of proteoglycan synthesis influences regeneration of goldfish retinal axons on polylysine and laminin. |
| PubMed: | HNK-1-reactive novel oligosaccharide, sulfate-O-3GlcA beta 1-4Xyl beta 1-(4-methylumbelliferone), synthesized by cultured human skin fibroblasts. |
| PubMed: | Identification of a novel glycosaminoglycan core-like molecule. I. 500 MHz 1H NMR analysis using a nano-NMR probe indicates the presence of a terminal alpha-GalNAc residue capping 4-methylumbelliferyl-beta-D-xylosides. |
| PubMed: | A novel oligosaccharide, GlcA beta 1-4Xyl beta 1-(4-methylumbelliferone), synthesized by human cultured skin fibroblasts. |
| PubMed: | A novel oligosaccharide, xylosyl beta 1-4xylosyl beta 1-(4-methylumbelliferone), synthesized by cultured human skin fibroblasts in the presence of 4-methylumbelliferyl-beta-D-xyloside. |
| PubMed: | A method for determination of galactosyltransferase I activity synthesizing the proteoglycan linkage region. |
| PubMed: | Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells. |
| PubMed: | Sulphation of proteochondroitin and 4-methylumbelliferyl beta-D-xyloside-chondroitin formed by mouse mastocytoma cells cultured in sulphate-deficient medium. |
| PubMed: | Simple measurement of glycosaminoglycan produced by cultured fibroblasts using 4-methylumbelliferyl beta-D-xyloside. |
| PubMed: | Heparin releases newly synthesized cell surface-associated apolipoprotein E from HepG2 cells. |
| PubMed: | Alpha- and beta-xylosides alter glycolipid synthesis in human melanoma and Chinese hamster ovary cells. |
| PubMed: | The neural cell adhesion molecule (NCAM) heparin binding domain binds to cell surface heparan sulfate proteoglycans. |
| PubMed: | Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix. |
| PubMed: | Characterization of beta-D-xyloside-induced glycosaminoglycans and oligosaccharides in cultured human skin fibroblasts. |
| PubMed: | Decreased thrombin affinity of cell-surface thrombomodulin following treatment of cultured endothelial cells with beta-D-xyloside. |
| PubMed: | Effect of forskolin on synthesis of xyloside-initiated glycosaminoglycans in embryonic chick chondrocytes. |
| PubMed: | Preparation and application of a fluorogenic substrate for endo-beta-xylosidase. |
| PubMed: | Inhibition of proteoglycan synthesis alters extracellular matrix deposition, proliferation, and cytoskeletal organization of rat aortic smooth muscle cells in culture. |
| PubMed: | Cerebellar granule cells contain a membrane mitogen for cultured Schwann cells. |
| PubMed: | Inhibition of endothelial cell morphogenetic interactions in vitro by alpha- and beta-xylosides. |
| PubMed: | Modulation of glycosaminoglycan production and antithrombin III binding by cultured aortic endothelial cells treated with 4-methylumbelliferyl-beta-D-xyloside. |
| PubMed: | Changes in glycosaminoglycan synthesis during the differentiation of HL-60 cells induced by 12-O-tetra-decanoylphorbol-13-acetate. |
| PubMed: | Effects of inhibition of proteoglycan synthesis on the differentiation of cultured rat Schwann cells. |
| PubMed: | Glycosaminoglycan metabolism of HL-60 cells during differentiation induction by tetradecanoylphorbol-13-acetate. |
| PubMed: | Sulfated proteoglycans produced by rat dorsal root ganglion cells. |
| PubMed: | Altered glycosaminoglycan production by HL-60 cells treated with 4-methylumbelliferyl-beta-D-xyloside. |
| PubMed: | A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation. |
| PubMed: | Increased sulphation level and altered composition of glycosaminoglycans synthesized by cultured smooth muscle cells in the presence of beta-D-xylosides. |
| PubMed: | Tissue interactions in the organization and maintenance of the muscle pattern in the chick limb. |
| PubMed: | Effect of 4-methylumbelliferyl-beta-d-xyloside on collagen synthesis in chick limb bud mesenchymal cell cultures. |
| PubMed: | Fluid and glycosaminoglycan excretion by chick embryos treated with a beta-D-xyloside. |
| PubMed: | Development of the biochemical and morphological changes induced by administration of a beta-xyloside to chick embryos. |
| PubMed: | Initiation of altered heparan sulphate on beta-D-xyloside in rat hepatocytes. |
| PubMed: | The action of somatomedin on glycosaminoglycan synthesis in cultured chick chondrocytes. |
| PubMed: | Changes in chemical composition of chick embryos treated with a beta-xyloside and a lathyrogen. |
| PubMed: | The effect of beta-xylosides on heparan sulfate synthesis by SV40-transformed Swiss mouse 3T3 cells. |
| PubMed: | The mode of action of 4-methylumbelliferyl beta-D-xyloside on the synthesis of chondroitin sulphate in embryonic-chicken sternum. |
| PubMed: | Glycosaminoglycan synthesis by cultured human skin fibroblasts after transformation with simian virus 40. |
| PubMed: | The effect of beta-D-xylosides on chondroitin sulphate biosynthesis in embryonic chicken cartilage in the absence of protein synthesis inhibitors. |
| PubMed: | Collagen synthesis and deposition in cartilage during disrupted proteoglycan production. |
| PubMed: | Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells. |
| PubMed: | Synthesis of a fluorogenic mucopolysaccharide by chondrocytes in cell culture with 4-methylumbelliferyl beta-D-xyloside. |
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