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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 900.10 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 566.00 °F. TCC ( 296.50 °C. ) (est)
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| logP (o/w): | 3.390 (est) |
| Soluble in: |
| | water, 611.2 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for poncirin usage levels up to: | | | not for fragrance use.
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| Recommendation for poncirin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 84718 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one |
| Chemidplus: | 0014941083 |
References:
| | 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 84718 |
| Pubchem (sid): | 135041975 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (S)-7-((2-O-(6- | deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one | | 7-[(2S,3R,4S,5S,6R)-4,5- | dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one | | iso | sakuranetin-7-O-neohesperidoside |
Articles:
| PubMed: | Drying effect on flavonoid composition and antioxidant activity of immature kumquat. |
| PubMed: | Determination of Flavanones in Orange Juices Obtained from Different Sources by HPLC/DAD. |
| PubMed: | Metabolism of Rutin and Poncirin by Human Intestinal Microbiota and Cloning of Their Metabolizing α-L-Rhamnosidase from Bifidobacterium dentium. |
| PubMed: | Hydrolysis of flavanone glycosides by β-glucosidase from Pyrococcus furiosus and its application to the production of flavanone aglycones from citrus extracts. |
| PubMed: | Biosynthesis of bioactive O-methylated flavonoids in Escherichia coli. |
| PubMed: | Characterization, Purification of Poncirin from Edible Citrus Ougan (Citrus reticulate cv. Suavissima) and Its Growth Inhibitory Effect on Human Gastric Cancer Cells SGC-7901. |
| PubMed: | Oxidative stress-related lung dysfunction by chromium(VI): alleviation by Citrus aurantium L. |
| PubMed: | Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques. |
| PubMed: | Degreening and postharvest storage influences 'Star Ruby' grapefruit (Citrus paradisi Macf.) bioactive compounds. |
| PubMed: | Poncirin prevents bone loss in glucocorticoid-induced osteoporosis in vivo and in vitro. |
| PubMed: | Effects of Ethyl Acetate Extract of Poncirus trifoliata Fruit for Glucocorticoid-Induced Osteoporosis. |
| PubMed: | A naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblasts. |
| PubMed: | Optimization of flavanones extraction by modulating differential solvent densities and centrifuge temperatures. |
| PubMed: | Poncirin promotes osteoblast differentiation but inhibits adipocyte differentiation in mesenchymal stem cells. |
| PubMed: | [Flavonoids--bioactive compounds in fruits juice]. |
| PubMed: | Simultaneous quantification of marker components in Ojeok-san by HPLC-DAD. |
| PubMed: | Development of radiation indicators to distinguish between irradiated and non-irradiated herbal medicines using HPLC and GC-MS. |
| PubMed: | Depressant effects of Clinopodium mexicanum Benth. Govaerts (Lamiaceae) on the central nervous system. |
| PubMed: | Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: potential prophylactic ingredients for functional foods application. |
| PubMed: | Protective effects of neohesperidin and poncirin isolated from the fruits of Poncirus trifoliata on potential gastric disease. |
| PubMed: | Bioactivity of flavonoid compounds from Poncirus trifoliata L. (Family: Rutaceae) against the dengue vector, Aedes aegypti L. (Diptera: Culicidae). |
| PubMed: | Biotransformation of ginsenoside Rb1, crocin, amygdalin, geniposide, puerarin, ginsenoside Re, hesperidin, poncirin, glycyrrhizin, and baicalin by human fecal microflora and its relation to cytotoxicity against tumor cells. |
| PubMed: | Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells. |
| PubMed: | One step purification of flavanone glycosides from Poncirus trifoliata by centrifugal partition chromatography. |
| PubMed: | A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata. |
| PubMed: | [Studies on chemical constituents from fruits of Paliurus ramosissimus]. |
| PubMed: | Passive cutaneous anaphylaxis-inhibitory activity of flavanones from Citrus unshiu and Poncirus trifoliata. |
| PubMed: | Phytochemical analysis of anti-atherogenic constituents of Xue-Fu-Zhu-Yu-Tang using HPLC-DAD-ESI-MS. |
| PubMed: | Fecal metabolic activities of herbal components to bioactive compounds. |
| PubMed: | Variance of common flavonoids by brand of grapefruit juice. |
| PubMed: | Anti-Helicobacter pylori activity of the metabolites of poncirin from Poncirus trifoliata by human intestinal bacteria. |
| PubMed: | Intestinal bacterial metabolism of flavonoids and its relation to some biological activities. |
| PubMed: | Simultaneous separation of flavanone glycosides and polymethoxylated flavones in citrus juices using liquid chromatography. |
| PubMed: | [Screening of phagocyte activators in plants; enhancement of TNF production by flavonoids]. |
| PubMed: | [Synthesis of poncirin, an isosakuranetin-7-beta-neohesperidoside from Poncirus trifoliata Raf]. |
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