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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
parenteral-frog LD50 200 mg/kg Bulletin des Sciences Pharmacologiques. Vol. 47, Pg. 33, 1940.
intraperitoneal-guinea pig LD50 162 mg/kg Bulletin des Sciences Pharmacologiques. Vol. 47, Pg. 33, 1940.
oral-mouse LDLo 125 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD "Zur Pharmakologie der Yohimbealkaloide, Dissertation," Langer, J., Institute fuer Pharmakologie und Experimentelle Therapie der Universitat Breslau, Poland, 1932Vol. -, Pg. -, 1932.
intravenous-rabbit LDLo 2 mg/kg "Zur Pharmakologie der Yohimbealkaloide, Dissertation," Langer, J., Institute fuer Pharmakologie und Experimentelle Therapie der Universitat Breslau, Poland, 1932Vol. -, Pg. -, 1932.
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| Dermal Toxicity: |
subcutaneous-dog LDLo 20 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
BEHAVIORAL: GENERAL ANESTHETIC "Zur Pharmakologie der Yohimbealkaloide, Dissertation," Langer, J., Institute fuer Pharmakologie und Experimentelle Therapie der Universitat Breslau, Poland, 1932Vol. -, Pg. -, 1932.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for rauwolscine hydrochloride usage levels up to: | | | not for fragrance use.
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| Recommendation for rauwolscine hydrochloride flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 197067 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride |
| Chemidplus: | 0006211321 |
| RTECS: | ZG1035000 for cas# 6211-32-1 |
References:
| | methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 197067 |
| Pubchem (sid): | 135175339 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | fauwolscine, hydrochloride | | | methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate hydrochloride | | | methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride | | | rauwolscine HCl | | 20-alpha- | yohimban-16-beta-carboxylic acid, 17-alpha-hydroxy-, methyl ester, hydrochloride | | | yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, monohydrochloride, (16beta,17alpha,20alpha)- (9CI) | | 20alpha- | yohimban-16beta-carboxylic acid, 17alpha-hydroxy-, methyl ester, monohydrochloride (8CI) | | alpha- | yohimbin hydrochloride | | alpha- | yohimbine hydrochloride |
Articles:
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