rhoifolin
rhoifoloside
 
Notes:
from many plants. Isol. from Citrus aurantium (Seville orange)
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      Product(s):
      17306-46-6 Rhoifolin
       
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CAS Number: 17306-46-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 241-335-4
FDA UNII: K86F9AKS2A
MDL: MFCD00016773
XlogP3-AA: -0.20 (est)
Molecular Weight: 578.52490000
Formula: C27 H30 O14
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 916.50 °C. @ 760.00 mm Hg (est)
Flash Point: 582.00 °F. TCC ( 305.40 °C. ) (est)
logP (o/w): -0.060 (est)
Soluble in:
 water, 1487 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Alfa Biotechnology
For experimental / research use only.
Rhoifolin 98%
BOC Sciences
For experimental / research use only.
Rhoifolin
ExtraSynthese
For experimental / research use only.
Rhoifolin (HPLC) ≥99%
Santa Cruz Biotechnology
For experimental / research use only.
Apigenin 7-O-neohesperidoside
Sigma-Aldrich: Sigma
For experimental / research use only.
Apigenin 7-O-neohesperidoside
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for rhoifolin usage levels up to:
 not for fragrance use.
 
Recommendation for rhoifolin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5483904
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 7-[(2S,3R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
Chemidplus: 0017306466
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References:
 7-[(2S,3R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 5483904
Pubchem (sid): 135044147
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
HMDB (The Human Metabolome Database): HMDB38848
FooDB: FDB018285
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 boehmeria nivea
Search Trop  Picture
 chamomile sweet false chamomile flower
Search Trop  Picture
 lemon leaf
Search Trop  Picture
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Synonyms:
 apigenin-7-O-rhamnoglucoside
4H-1-benzopyran-4-one, 7-((2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-
7-((2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one
7-[(2S,3R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
 rhoifoloside
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Articles:
PubMed: Comparison of Flavonoid Compounds in the Flavedo and Juice of Two Pummelo Cultivars (Citrus grandis L. Osbeck) from Different Cultivation Regions in China.
PubMed: Drying effect on flavonoid composition and antioxidant activity of immature kumquat.
PubMed: [Chemical constituents of Fortunella margarita fruits].
PubMed: [Quantitative analysis of six flavonoids of hongzhu capsule by QAMS].
PubMed: [Flavonoid glycosides from leaves of Turpinia arguta and their anti-inflammatory activity].
PubMed: HPLC with quadrupole TOF-MS and chemometrics analysis for the characterization of Folium Turpiniae from different regions.
PubMed: Inhibition of angiotensin-converting enzyme activity by flavonoids: structure-activity relationship studies.
PubMed: HPLC-PDA-MS and NMR characterization of a hydroalcoholic extract of Citrus aurantium L. var. amara peel with antiedematogenic activity.
PubMed: Study on impurities in naringin extracted from Citrus grandis 'tomentosa'.
PubMed: [Chemical constituents from stems of Lonicera japonica].
PubMed: Two new C-glucosyl benzoic acids and flavonoids from Mallotus nanus and their antioxidant activity.
PubMed: Flavonoid composition and antioxidant activity of juices from Chinotto ( Citrus x myrtifolia Raf.) fruits at different ripening stages.
PubMed: Insulin-Mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells.
PubMed: Evaluation of flavonoids and furanocoumarins from Citrus bergamia (Bergamot) juice and identification of new compounds.
PubMed: Bioactivity of flavonoid compounds from Poncirus trifoliata L. (Family: Rutaceae) against the dengue vector, Aedes aegypti L. (Diptera: Culicidae).
PubMed: Influence of postharvest hot water treatment on nutritional and functional properties of kumquat (Fortunella japonica Lour. Swingle Cv. Ovale) fruit.
PubMed: Flavonoid glycosides in bergamot juice (Citrus bergamia Risso).
PubMed: Flavonoid composition of fruit tissues of citrus species.
PubMed: Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.
PubMed: Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations.
PubMed: Antioxidative glycosides from the leaves of Ligustrum robustum.
PubMed: Protective effects of some flavonoids on the renal cellular membrane.
PubMed: Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid.
PubMed: Determination of rhoifolin and daidzin in human plasma by high-performance liquid chromatography.
PubMed: [The contents of sabal fruits and testing of their anti-inflammatory effect].
PubMed: Flavonoids as antioxidants evaluated by in vitro and in situ liver chemiluminescence.
PubMed: Flavanone glycosides as oviposition stimulants in a papilionid butterfly,Papilio protenor.
PubMed: [Flavoneglycosides in the flowers of Paeonia arborea and P. suffruticosa].
PubMed: [Studies on the constituents of Evodiopanax innovans nakai. I. Isolation of maltol and rhoifolin from the leaves].
PubMed: Isolation of rhoifolin from Chorisia species (Bombacaceae).
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