| PubMed: | Micropropagation and validation of genetic and biochemical fidelity amongst regenerants of Cassia angustifolia Vahl employing RAPD marker and HPLC. |
| PubMed: | Monitoring of 29 weight loss compounds in foods and dietary supplements by LC-MS/MS. |
| PubMed: | Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract. |
| PubMed: | Simultaneous analysis and quantification of markers of manjisthadi churna using high performance thin layer chromatography. |
| PubMed: | Commentary on 'Osmotic and stimulant laxatives for the management of childhood constipation'. |
| PubMed: | Cochrane Review: Osmotic and stimulant laxatives for the management of childhood constipation (Review). |
| PubMed: | Chemical differentiation of Da-Cheng-Qi-Tang, a Chinese medicine formula, prepared by traditional and modern decoction methods using UPLC/Q-TOFMS-based metabolomics approach. |
| PubMed: | Bioactivities and serum pharmacochemistry of Qi-Wei-Xiao-Yan-Tang. |
| PubMed: | The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice. |
| PubMed: | Study on spectrum-effect relationship of rhizoma Rhei, cortex Magnoliae Officinalis, fructus Aurantii Immaturus and their formula. |
| PubMed: | Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery. |
| PubMed: | Constipation and aspiration pneumonia. |
| PubMed: | Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model. |
| PubMed: | [Analysis on changes of purgative biopotency in different processed products of rhubarb]. |
| PubMed: | Promotion of intestinal peristalsis by Bifidobacterium spp. capable of hydrolysing sennosides in mice. |
| PubMed: | Inhibition of antigen trafficking through scavenger receptor A. |
| PubMed: | Chemical-based species classification of rhubarb using simultaneous determination of five bioactive substances by HPLC and LDA analysis. |
| PubMed: | High-performance liquid chromatographic determination and metabolic study of sennoside a in daiokanzoto by mouse intestinal bacteria. |
| PubMed: | The influence of glycyrrhiza and antibiotics on the purgative action of sennoside a from Daiokanzoto in mice. |
| PubMed: | Exposure to sennoside-digoxin interaction and risk of digoxin toxicity: a population-based nested case-control study. |
| PubMed: | [Determination of sennoside A and sennoside B simultaneously in health food by HPLC]. |
| PubMed: | Prospective randomized comparison of oral sodium phosphate and sennoside A+B calcium lavage for colonoscopy preparation. |
| PubMed: | Ultra-performance LC-photodiode array-eλ-ESI-MS/MS screening method for the detection of radical-scavenging natural antioxidants from radix et rhizoma Rhei. |
| PubMed: | Effects of optimized-SopungSunkiwon on memory impairment and enhancement. |
| PubMed: | Acute hemorrhagic colitis following administration of sennosides for colon cleansing. |
| PubMed: | Simple and rapid analysis of sennoside A and sennoside B contained in crude drugs and crude drug products by solid-phase extraction and high-performance liquid chromatography. |
| PubMed: | Simultaneous analysis of nine components in patch preparations of Ru-Yi-Jin-Huang-San by high-performance liquid chromatography. |
| PubMed: | [Study on processed senna found in health teas]. |
| PubMed: | Stimulatory action of mitemcinal (GM-611), an acid-resistant non-peptide motilin receptor agonist, on colonic motor activity and defecation: spontaneous and mitemcinal-induced giant migrating contractions during defecation in dogs. |
| PubMed: | Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells. |
| PubMed: | Development of eastern blotting technique for sennoside A and sennoside B using anti-sennoside A and anti-sennoside B monoclonal antibodies. |
| PubMed: | Enzyme-linked immunosorbent assay for total sennosides using anti-sennside A and anti-sennoside B monoclonal antibodies. |
| PubMed: | Efficacy of prokinetic agents in improving bowel preparation for colonoscopy. |
| PubMed: | [Determination of five primary chemical constituents in Cassia angustifolia by HPLC]. |
| PubMed: | Production, characterization of a monoclonal antibody against aristolochic acid-II and development of its assay system. |
| PubMed: | A comparison of sennosides-based bowel protocols with and without docusate in hospitalized patients with cancer. |
| PubMed: | Acute generalized exanthematous pustulosis caused by sennoside in a patient with multiple myeloma. |
| PubMed: | The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia. |
| PubMed: | Regionally differential effects of sennoside A on spontaneous contractions of colon in mice. |
| PubMed: | Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers--an in vitro model for intestinal absorption. |
| PubMed: | [Comparative studies on purgative potency among three spieces of certified rhubarb]. |
| PubMed: | Determination of 19 rhubarb constituents by high-performance liquid chromatography-ultraviolet-mass spectrometry. |
| PubMed: | Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis. |
| PubMed: | Increasing sennoside yields in tinnevelly senna (Cassia angustifolia) I: effects of drought, foliar nitrogen spray and crop type. |
| PubMed: | [Bowel lavage solutions: are senosidos A+B harmless?]. |
| PubMed: | The bowel cleansing for colonoscopy. A randomized trial comparing three methods. |
| PubMed: | Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2). |
| PubMed: | Analysis of phenolic compounds in rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry. |
| PubMed: | Erythema multiforme-like drug eruption caused by sennoside. |
| PubMed: | Liquid chromatographic determination of sennosides in Cassia angustifolia leaves. |
| PubMed: | Sennosides A and B production by hairy roots of Senna alata (L.) Roxb. |
| PubMed: | Safety and efficacy of NT, an herbal supplement, in treating human obesity. |
| PubMed: | Advice needed. |
| PubMed: | Combined low volume polyethylene glycol solution plus stimulant laxatives versus standard volume polyethylene glycol solution: a prospective, randomized study of colon cleansing before colonoscopy. |
| PubMed: | The influence of the sennosides on absorption of glycyrrhetic acid in rats. |
| PubMed: | Insulin sensitizing and alpha-glucoamylase inhibitory action of sennosides, rheins and rhaponticin in Rhei Rhizoma. |
| PubMed: | High-performance liquid chromatographic method for simultaneous quantification of eight major biologically active ingredients in 'Da-Chai-Hu-Tang' preparation. |
| PubMed: | Simultaneous determination of anthraquinones, their 8-beta-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis. |
| PubMed: | [Determination of sennoside A in rhubarb extracts by HPLC]. |
| PubMed: | [Determination of sennosides and degraded products in the process of sennoside metabolism by HPLC]. |
| PubMed: | In vitro studies on guar gum based formulation for the colon targeted delivery of Sennosides. |
| PubMed: | [Development of rapid and sensitive screening methods for natural products using specific monoclonal antibodies]. |
| PubMed: | Compatibility of sennoside A and B with pharmaceutical excipients. |
| PubMed: | A case of interstitial granulomatous drug reaction due to sennoside. |
| PubMed: | Development of a one-step immunochromatographic strip test for the detection of sennosides A and B. |
| PubMed: | [Comparison of the effectiveness and tolerability of the saccharosum-sennosid-B solution and sodium-picosulfate in preparation for colonoscopy. Prospective, multicenter, randomized study]. |
| PubMed: | Pharmacokinetics of rhein from Onpi-to, an Oriental herbal medicine, in rats. |
| PubMed: | Validated HPLC method for determination of sennosides A and B in senna tablets. |
| PubMed: | An improved method for the analysis of sennosides in Cassia angustifolia by high-performance liquid chromatography. |
| PubMed: | [Origin of sennosides in health teas including Malva leaves]. |
| PubMed: | Production of monoclonal antibodies against a major purgative component, sennoside B, their characterization and use in ELISA. |
| PubMed: | Apoptosis induction by sennoside laxatives in man; escape from a protective mechanism during chronic sennoside use? |
| PubMed: | [The effects of kampo-formulation and the constituting crude drugs, prescribed for the treatment of peptic ulcer on H,K-ATPase activity]. |
| PubMed: | [Intestinal preparation with an osmotic solution for edema with double contrast media]. |
| PubMed: | Prospective randomized trial comparing bowel cleaning preparations for colonoscopy. |
| PubMed: | Calcium polycarbophil, a water absorbing polymer, increases bowel movement and prevents sennoside-induced diarrhea in dogs. |
| PubMed: | [The double-contrast enema. The Genoa technic between tradition and progress]. |
| PubMed: | Amitriptyline-induced constipation in cynomolgus monkeys is beneficial for the evaluation of laxative efficacy. |
| PubMed: | Estimation of individual sennosides in plant materials and marketed formulations by an HPTLC method. |
| PubMed: | Significant increase in prostaglandin E-main urinary metabolite by laxative administration: comparison with ulcerative colitis. |
| PubMed: | A blinded, randomized comparison of a novel, low-dose, triple regimen with fleet phospho-soda: a study of colon cleanliness, speed and success of colonoscopy. |
| PubMed: | Does senna extract promote growth of aberrant crypt foci and malignant tumors in rat colon? |
| PubMed: | [Comparative study of the use of sennoside A and B vs polyethylene glycol and electrolytes in anterograde preparation of the colon]. |
| PubMed: | Do magnesium ions influence barium mucosal coating of the large bowel? |
| PubMed: | Review article: anthranoid laxatives and their potential carcinogenic effects. |
| PubMed: | Bowel preparation for the double-contrast barium enema: how to maintain coating with cleansing? |
| PubMed: | A new magnesium-containing PEG-electrolyte solution for the oral lavage of the colon. |
| PubMed: | [Determination of sennoside A and sennoside B in formulation using capillary electrophoresis]. |
| PubMed: | The effect of sennosides on bacterial translocation and survival in a model of acute hemorrhagic pancreatitis. |
| PubMed: | Genotoxicity of sennosides on the bone marrow cells of mice. |
| PubMed: | Analysis of sennosides A and B from Dieter's tea by HPLC-diode array spectrophotometry and negative ion electrospray mass spectrometry. |
| PubMed: | The effect of sennosides on colonic mucosal histology and bowel preparation. |
| PubMed: | Randomized comparison of two preoperative methods for preparation of the colon: oral administration of a solution of polyethylene glycol plus electrolytes and total parenteral nutrition. |
| PubMed: | Correction of outflow obstruction with the use of sennosides in CAPD patients. |
| PubMed: | Purification and characterization of a novel sennoside-hydrolyzing beta-glucosidase from Bifidobacterium sp. strain SEN, a human intestinal anaerobe. |
| PubMed: | A sennoside-hydrolyzing beta-glucosidase from Bifidobacterium sp. strain SEN is inducible. |
| PubMed: | [Use of sennosides A + B in the preparation of the colon for endoscopy]. |
| PubMed: | Evaluation of the potential carcinogenic activity of Senna and Cascara glycosides for the rat colon. |
| PubMed: | [The mechanism of action of sennosides]. |
| PubMed: | [Sennosides Reference Standard (Control 951) of the National Institute of Health Sciences]. |
| PubMed: | Antibacterial activity of bowel-cleansing agents: implications of antibacteroides activity of senna. |
| PubMed: | [Effects of emodin, sennosides and rheum polysaccharides on free calcium in isolated rat liver cells]. |
| PubMed: | [High performance liquid chromatographic determination of sennoside A in maren pills]. |
| PubMed: | Determination of eight constituents of hsiao-cheng-chi-tang by high-performance liquid chromatography. |
| PubMed: | [Effects of sennosides, rhubarb polysaccharides and emodin on the cytoplasmic free calcium in isolated rat brain cells]. |
| PubMed: | Potassium supplements prevent serious hypokalaemia in colon cleansing. |
| PubMed: | Study of various rhubarbs regarding the cathartic effect and endotoxin-induced disseminated intravascular coagulation. |
| PubMed: | Isolation of a human intestinal anaerobe, Bifidobacterium sp. strain SEN, capable of hydrolyzing sennosides to sennidins. |
| PubMed: | Sennoside-induced secretion is not caused by changes in mucosal permeability or Na+,K(+)-ATPase activity. |
| PubMed: | Analytics of senna drugs with regard to the toxicological discussion of anthranoids. |
| PubMed: | Metabolism and pharmacokinetics of anthranoids. |
| PubMed: | Serotonin antagonists inhibit sennoside-induced fluid secretion and diarrhea. |
| PubMed: | Anthranoids and the mucosal immune system of the colon. |
| PubMed: | Suppression of the purgative action of rhein anthrone, the active metabolite of sennosides A and B, by calcium channel blockers, calmodulin antagonists and indomethacin. |
| PubMed: | Two-year carcinogenicity study with sennosides in the rat: emphasis on gastro-intestinal alterations. |
| PubMed: | Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice. |
| PubMed: | The senna drug and its chemistry. |
| PubMed: | Light and electron-microscopic changes in the colon of the guinea pig after treatment with anthranoid and non-anthranoid laxatives. |
| PubMed: | Chronic sennoside treatment does not cause habituation and secondary hyperaldosteronism in rats. |
| PubMed: | In vivo motility of rat colon chronically pretreated with sennosides. |
| PubMed: | Effects of long-term sennoside treatment on in vitro motility of rat colon. |
| PubMed: | Sennoside-induced secretion and its relevance for the laxative effect. |
| PubMed: | Cleavages of the O- and C-glucosyl bonds of anthrone and 10,10'-bianthrone derivatives by human intestinal bacteria. |
| PubMed: | Rhein and aloe-emodin kinetics from senna laxatives in man. |
| PubMed: | Effects of sennosides and nonanthranoid laxatives on cytochemistry of epithelial cells in rat colon. |
| PubMed: | [Effects of sennosides on cellular electric activities in smooth muscle cells of guinea pig taenia coli]. |
| PubMed: | [Identification and determination of marker substances in niuhuang jiedu pian by three dimensional HPLC]. |
| PubMed: | Bowel preparation for the total colonoscopy by 2,000 ml of balanced lavage solution (Golytely) and sennoside. |
| PubMed: | Influence of rhein anthrone and rhein on small intestine transit rate in rats: evidence of prostaglandin mediation. |
| PubMed: | [The effects of dachengqi decoction, shaogan decoction, emodin and sennoside on the histamine level of intestinal mucosa in intestinally obstructed rats]. |
| PubMed: | [Determination of sennoside A in oriental pharmaceutical decoctions containing Rhei Rhizoma by ion-pair high-performance liquid chromatography]. |
| PubMed: | A trial to assess the effectiveness of bowel preparation prior to intravenous urography. |
| PubMed: | [Are drugs with anthranoid group harmful or non-harmful laxatives?]. |
| PubMed: | Suppression of the purgative action of rhein anthrone, the active metabolite of sennosides A and B, by indomethacin in rats. |
| PubMed: | Perfusion of rat colon with sennosides, rhein and rheinanthrone. Concentration-related histamine release. |
| PubMed: | [Electromyography of the human colon]. |
| PubMed: | The sennoside constituents of rhei rhizoma and sennae folium as inhibitors of serum monoamine oxidase. |
| PubMed: | Effects of sennosides on colonic myoelectrical activity in man. |
| PubMed: | Effects of sennosides A + B and bisacodyl on rat large intestine. |
| PubMed: | Sennosides do not kill myenteric neurons in the colon of the rat or mouse. |
| PubMed: | Changes in colonic motility induced by sennosides in dogs: evidence of a prostaglandin mediation. |
| PubMed: | The effect of different storage conditions on the chemical stability, laxative effect and acute toxicity of sennoside solutions. |
| PubMed: | Tissue culture of rhubarb and isolation of sennosides from the callus. |
| PubMed: | Combined manometric and radiological study of the changes in colonic motility induced by sennosides in rats. |
| PubMed: | In vitro effects of anthraquinones on rat intestine and uterus. |
| PubMed: | Effect of sennosides and related compounds on intestinal transit in the rat. |
| PubMed: | Effect of sennosides on colon motility in cats. |
| PubMed: | Milk transfer of rhein in the rhesus monkey. |
| PubMed: | Evaluation of the effects of sennosides on uterine motility in the pregnant ewe. |
| PubMed: | Long-term mucosal alterations by sennosides and related compounds. |
| PubMed: | Electron microscopical studies on rat intestine after long-term treatment with sennosides. |
| PubMed: | Toxic effects of sennosides in laboratory animals and in vitro. |
| PubMed: | Metabolism of sennosides by human intestinal bacteria. |
| PubMed: | New aspects on the metabolism of the sennosides. |
| PubMed: | Metabolism of sennosides--an overview. |
| PubMed: | Sennosides and human colonic motility. |
| PubMed: | Effect of sennosides on colon motility in dogs. |
| PubMed: | Studies in the field of drugs containing anthraquinone derivatives. XXXVI. The metabolism of cascarosides by intestinal bacteria. |
| PubMed: | Prostaglandin-mediated action of sennosides. |
| PubMed: | Involvement of prostaglandin E-like material in the purgative action of rhein anthrone, the intraluminal active metabolite of sennosides A and B in mice. |
| PubMed: | Rapid and simple determination of sennoside A and B in rhei rhizoma by ion-pair high-performance liquid chromatography. |
| PubMed: | Non-enzymatic reduction of sennidins and sennosides by reduced flavin. |
| PubMed: | Effect of changing transit time on colonic microbial metabolism in man. |
| PubMed: | Irritable bowel-type symptoms in spontaneous and induced constipation. |
| PubMed: | [Mode of action of anthraquinone laxatives on the rat]. |
| PubMed: | Reproductive toxicological investigations with sennosides. |
| PubMed: | [Clinical effect and experimental study on folium Sennae in acute gastroduodenal hemorrhage]. |
| PubMed: | Dual effect of orally administered sennosides on large intestine transit and fluid absorption in the rat. |
| PubMed: | Acceleration of large intestine transit time in rats by sennosides and related compounds. |
| PubMed: | [Determination of anthraquinone derivatives in rhubarb grown for export]. |
| PubMed: | Enzymatic reduction of sennidin and sennoside in Peptostreptococcus intermedius. |
| PubMed: | Isolation of a new aloe-emodin dianthrone diglucoside from senna and its potentiating effect on the purgative activity of sennoside A in mice. |
| PubMed: | Comparative physiological disposition of some anthraquinone glycosides and aglycones. |
| PubMed: | Decrease of cholesterol and triglycerides serum levels by metoclopramide and by sennosides. |
| PubMed: | [Acute hemorrhagic colitis following administration of sennosides A and B]. |
| PubMed: | Ultrastructure of mouse intestinal mucosa and changes observed after long term anthraquinone administration. |
| PubMed: | [High performance liquid chromatography of the evolution of sennosides A and B in solution]. |
| PubMed: | [Measurement of the intestinal clearance of alpha 1-antitrypsin and the exchangeable potassium pool in elderly patients treated with anthraquinone glycosides]. |
| PubMed: | A physiological appraisal of polyethylene glycol and a balanced electrolyte solution as bowel preparation. |
| PubMed: | Anthraquinone-induced clubbing associated with laxative abuse. |
| PubMed: | Mutagenicity of anthraquinones in the Salmonella preincubation test. |
| PubMed: | Sennosides and carbohydrates in developing pods of Cassia species. |
| PubMed: | Left-sided colonoscopy in screening programs. What preparation? |
| PubMed: | Metabolism of sennosides by intestinal flora. |
| PubMed: | Faecal peritonitis after laxative preparation for barium enema. |
| PubMed: | Faecal peritonitis after laxative preparation for barium enema. |
| PubMed: | Qualitative and quantitative interactions between the sennosides and some human intestinal bacteria. |
| PubMed: | The metabolism of sennosides A and B by the intestinal microflora: in vitro and in vivo studies on the rat and the mouse. |
| PubMed: | Potentiating effect of sennoside C on purgative activity of sennoside A in mice. |
| PubMed: | High-pressure liquid chromatographic analysis of sennosides A and B purgative drugs. |
| PubMed: | A screening method for establishing laxative abuse. |
| PubMed: | Formation and distribution of sennosides in Cassia angustifolia, as determined by a sensitive and specific radioimmunoassay. |
| PubMed: | Effects of sodium picosulfate, bisacodyl and sennoside in cultured human, rat and rabbit liver cells. |
| PubMed: | Metabolism of sennosides by human intestinal bacteria. |
| PubMed: | Spectrophotometric estimation of sennosides and rhein glycosides in senna and its preparations. |
| PubMed: | [Simple, safe and effective method of intestinal cleansing without enemas]. |
| PubMed: | Analytical studies on the active constituents in crude drugs. IV. Determination of sennosides in senna and formulations by high-performance liquid chromatography. |
| PubMed: | [A preliminary study of the correlation between phylogeny, chemical constituents and therapeutic effects of Rheum species]. |
| PubMed: | Metabolic activation of sennoside A in mice. |
| PubMed: | Effect of ricinoleic acid and other laxatives on net water flux and prostaglandin E release by the rat colon. |
| PubMed: | [Isolation and structural definition of a new sennoside from Cassia senna L. (author's transl)]. |
| PubMed: | [Transport and mode of action of sennosides]. |
| PubMed: | The diffusion of sennoside A through a cellulose membrane. |
| PubMed: | [Quantitative chromatographic determination of the active principles of senna (sennoside A, sennoside B)]. |
| PubMed: | LAXATIVE EFFECT OF SENNOSIDE A AND PLACEBO IN A DOUBLE-BLIND CROSS-OVER TEST. |
| PubMed: | [Postoperative use of sennoside A and B]. |