|
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 943.90 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 593.00 °F. TCC ( 311.90 °C. ) (est)
|
| logP (o/w): | 3.830 (est) |
| Soluble in: |
| | water, 2.652 mg/L @ 25 °C (est) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for tiliroside usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for tiliroside flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| EPI System: | View |
| Cancer Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5320686 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate |
| Chemidplus: | 0020316625 |
References:
| | [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5320686 |
| Pubchem (sid): | 135151859 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| [(2R,3S,4S,5R,6S)-6-[5,7- | dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate | | | kaempferol-3-O[-6-O-trans-p-coumaroyl-β-glucopyranoside | | 2- | propenoic acid, 3-(4-hydroxyphenyl)-, 6'-ester with 3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Articles:
| PubMed: | The Pavonia xanthogloea (Ekman, Malvaceae): Phenolic compounds quantification, anti-oxidant and cytotoxic effect on human lymphocytes cells. |
| PubMed: | Pine (Pinus morrisonicola Hayata) Needle Extracts Sensitize GBM8901 Human Glioblastoma Cells to Temozolomide by Downregulating Autophagy and O(6)-Methylguanine-DNA Methyltransferase Expression. |
| PubMed: | Tiliroside, a dietary glycosidic flavonoid, inhibits TRAF-6/NF-κB/p38-mediated neuroinflammation in activated BV2 microglia. |
| PubMed: | Microphynolides A and B, new spiro-γ-lactone glycosides from Thymelaea microphylla. |
| PubMed: | Studies on cytotoxic constituents from the leaves of Elaeagnus oldhamii Maxim. in non-small cell lung cancer A549 cells. |
| PubMed: | [Determination of ellagic acid, flavonoids and goshonoside-F5 in Rubi Fructus by HPLC]. |
| PubMed: | Antiurease activity of plants growing in the Czech Republic. |
| PubMed: | Rosehip Extract Inhibits Lipid Accumulation in White Adipose Tissue by Suppressing the Expression of Peroxisome Proliferator-activated Receptor Gamma. |
| PubMed: | Isolation of natural compounds from Phlomis stewartii showing α-glucosidase inhibitory activity. |
| PubMed: | Isolation of new flavan-3-ol and lignan glucoside from Loropetalum chinense and their antimicrobial activities. |
| PubMed: | Mechanism of the antihypertensive and vasorelaxant effects of the flavonoid tiliroside in resistance arteries. |
| PubMed: | Flavonoids from Pseudotsuga menziesii. |
| PubMed: | Phenolic antioxidants from Rosa soulieana flowers. |
| PubMed: | Functional screening of metagenome and genome libraries for detection of novel flavonoid-modifying enzymes. |
| PubMed: | Investigation into biologically active constituents of Geum rivale L. |
| PubMed: | Anti-oxidative and cholinesterase inhibitory effects of leaf extracts and their isolated compounds from two closely related Croton species. |
| PubMed: | New phenolic compounds with anti-adipogenic activity from the aerial parts of Pulsatilla koreana. |
| PubMed: | A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii. |
| PubMed: | Preparative purification of five bioactive components from Agrimonia pilosa Ledeb by high-speed counter-current chromatography. |
| PubMed: | Isolation and characterization of new ceramides from aerial parts of Lepidaploa cotoneaster. |
| PubMed: | On-line (HPLC-NMR) and off-line phytochemical profiling of the Australian plant, Lasiopetalum macrophyllum. |
| PubMed: | Microarray-based mRNA expression profiling of leukemia cells treated with the flavonoid, casticin. |
| PubMed: | Flavonoid constituents and free radical scavenging activity of Alchemilla mollis. |
| PubMed: | On-line (HPLC-NMR) and off-line phytochemical profiling of the Australian plant, Lasiopetalum macrophyllum. |
| PubMed: | Effects of pH on the ability of flavonoids to act as Pickering emulsion stabilizers. |
| PubMed: | Tiliroside, a glycosidic flavonoid, inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract. |
| PubMed: | Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice. |
| PubMed: | Synthesis and biological activity of novel tiliroside derivants. |
| PubMed: | Isolated compounds from Sorghum bicolor L. inhibit the classical pathway of the complement. |
| PubMed: | Inhibition effects of isolated compounds from Artemisia rubripes Nakai of the classical pathway on the complement system. |
| PubMed: | Isolation and characterisation of novel antioxidant constituents of Croton zambesicus leaf extract. |
| PubMed: | Extracts and constituents of Rubus chingii with 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity. |
| PubMed: | In vitro activity of dietary flavonol congeners against human cancer cell lines. |
| PubMed: | Anticomplement activity of polyacetylenes from leaves of Dendropanax morbifera Leveille. |
| PubMed: | Identification of trans-tiliroside as active principle with anti-hyperglycemic, anti-hyperlipidemic and antioxidant effects from Potentilla chinesis. |
| PubMed: | Docking study of HIV-1 reverse transcriptase with phytochemicals. |
| PubMed: | Tiliroside-derivatives enhance GLUT4 translocation via AMPK in muscle cells. |
| PubMed: | Particle-stabilizing effects of flavonoids at the oil-water interface. |
| PubMed: | Synthesis and biological activity of trans-tiliroside derivatives as potent anti-diabetic agents. |
| PubMed: | Reversible inhibition of three important human liver cytochrome p450 enzymes by tiliroside. |
| PubMed: | Scopoletin from the flower buds of Magnolia fargesii inhibits protein glycation, aldose reductase, and cataractogenesis ex vivo. |
| PubMed: | Phenolic glycosides from Agrimonia pilosa. |
| PubMed: | Effect of neuroprotective flavonoids of Agrimonia eupatoria on glutamate-induced oxidative injury to HT22 hippocampal cells. |
| PubMed: | Determination of the phenolic content and antioxidant potential of crude extracts and isolated compounds from leaves of Cordia multispicata and Tournefortia bicolor. |
| PubMed: | Fluorescence studies of interaction between flavonol p-coumaroylglucoside tiliroside and bovine serum albumin. |
| PubMed: | A natural approach to soothing atopic skin. |
| PubMed: | Flavonoids from the stems of Croton caudatus Geisel. var. tomentosus Hook. |
| PubMed: | The potential mechanism of tiliroside-dependent inhibition of t-butylhydroperoxide-induced oxidative stress in endometrial carcinoma cells. |
| PubMed: | Determination of polyphenolics in extracts of Potentilla species by high-performance thin-layer chromatography photodensitometry method. |
| PubMed: | Bioactivity of flavonoids isolated from Lychnophora markgravii against Leishmania amazonensis amastigotes. |
| PubMed: | Tyrosinase inhibitory effect and inhibitory mechanism of tiliroside from raspberry. |
| PubMed: | [RP-HPLC determination of tiliroside in Daphne genkwa]. |
| PubMed: | [Studies on isolation and identification of flavonoids in herbs of Agrimonia pilosa]. |
| PubMed: | Modulation of drug resistance in Staphylococcus aureus by a kaempferol glycoside from Herissantia tiubae (Malvaceae). |
| PubMed: | Studies on the phenylethanoid glycosides with anti-complement activity from Paulownia tomentosa var. tomentosa wood. |
| PubMed: | Human DNA topoisomerase inhibitors from Potentilla argentea and their cytotoxic effect against MCF-7. |
| PubMed: | Flavonoids from Tilia americana with anxiolytic activity in plus-maze test. |
| PubMed: | Acetylcholinesterase inhibition by flavonoids from Agrimonia pilosa. |
| PubMed: | [Studies on optimal extraction conditions of flavonoid from the flowers of Edgeworthia chrysantha]. |
| PubMed: | Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: a comparative study. |
| PubMed: | Potent anti-obese principle from Rosa canina: structural requirements and mode of action of trans-tiliroside. |
| PubMed: | Antiviral and antimicrobial assessment of some selected flavonoids. |
| PubMed: | Additional antiprotozoal flavonol glycosides of the aerial parts of Helianthemum glomeratum. |
| PubMed: | Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation. |
| PubMed: | In vivo antigiardial activity of three flavonoids isolated of some medicinal plants used in Mexican traditional medicine for the treatment of diarrhea. |
| PubMed: | Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida. |
| PubMed: | Cytotoxic C-benzylated chalcone and other constituents of Ellipeiopsis cherrevensis. |
| PubMed: | A potent anti-complementary acylated sterol glucoside from Orostachys japonicus. |
| PubMed: | Flavonoids from the leaves of Litsea japonica and their anti-complement activity. |
| PubMed: | [Study on flavonoids from leaf of Ipomoea batatas]. |
| PubMed: | [Studies on the chemical constituents from Fructus Rubi]. |
| PubMed: | Inhibitory effects of the flavonoids isolated from Waltheria indica on the production of NO, TNF-alpha and IL-12 in activated macrophages. |
| PubMed: | A new heptasubstituted (E)-aurone glucoside and other aromatic compounds of Gomphrena agrestis with biological activity. |
| PubMed: | [Studies on chemical constituents in fruit of Rubus chingii]. |
| PubMed: | [Studies on flavonoids of Anaphalis sinica]. |
| PubMed: | Kaempferol and quercetin glycosides from Rubus idaeus L. leaves. |
| PubMed: | [Chemical constituents from the fruit of Rosa bella Rehd. et Wils]. |
| PubMed: | Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside. |
| PubMed: | Bioactive phenolic derivatives from Acaena splendens methanol extract. |
| PubMed: | Hepatoprotective principles from the flowers of Tilia argentea (linden): structure requirements of tiliroside and mechanisms of action. |
| PubMed: | In vitro antimicrobial activity of extracts and isolated constituents of Rubus ulmifolius. |
| PubMed: | Flavonoid compounds in the flowers of Kitaibelia vitifolia Willd. (Malvaceae). |
| PubMed: | Kaempferol glycosides from Siparuna apiosyce. |
| PubMed: | CYTOTOXIC ACTIVITY OF KAEMPFEROL GLYCOSIDES AGAINST HUMAN LEUKAEMIC CELL LINES IN VITRO. |
| PubMed: | Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro. |
| PubMed: | Cytotoxic and antiproliferative effects of heptaacetyltiliroside on human leukemic cell lines. |
| PubMed: | Antiprotozoal properties of Helianthemum glomeratum. |
| PubMed: | Anti-complement activity of tiliroside from the flower buds of Magnolia fargesii. |
| PubMed: | Biotransformation of the flavonoid tiliroside to 7-methylether tiliroside: bioactivity of this metabolite and of its acetylated derivative. |
| PubMed: | Phenylpropanoid esters from Lamium album flowers. |
| PubMed: | Tiliroside from the seeds of Eremocarpus setigerus. |
| PubMed: | Identification of carcinogenic tannin isolated from Bracken fern (Pteridium aquilinum). |
| PubMed: | [The flavonoids of the platan (Platanus occidentalis L.). Isolation of tiliroside from the leaves and of hyperoside from the male inflorescence]. |
|