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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 898.80 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 571.00 °F. TCC ( 299.50 °C. ) (est)
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| logP (o/w): | 1.860 (est) |
| Soluble in: |
| | water, 1.1e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for vitexin 2-O-rhamnoside usage levels up to: | | | not for fragrance use.
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| Recommendation for vitexin 2-O-rhamnoside flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5282151 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | 8-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| Chemidplus: | 0064820991 |
References:
| | 8-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5282151 |
| Pubchem (sid): | 135159752 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (1S)-1,5- | anhydro-2-O-(6-deoxy-a-L-mannopyranosyl)-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol | | | apigenin-8-C-glucoside-2'-rhamnoside | | 8-[(2S,3R,4S,5S,6R)-4,5- | dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one | | 2-O- | rhamnosylvitexin | | 2''-O- | rhamnosylvitexin | | | vitexin-2''-O-rhamnoside |
Articles:
| PubMed: | Effects of vitexin-2"-O-rhamnoside and vitexin-4"-O-glucoside on growth and oxidative stress-induced cell apoptosis of human adipose-derived stem cells. |
| PubMed: | Tissue distribution comparison between healthy and fatty liver rats after oral administration of hawthorn leaf extract. |
| PubMed: | Qualitative and quantitative analysis of phenolics in Tetrastigma hemsleyanum and their antioxidant and antiproliferative activities. |
| PubMed: | Nutritional and functional potential of Beta vulgaris cicla and rubra. |
| PubMed: | An enzyme-linked immunosorbent assay for the measurement of plasma flavonoids in mice fed apigenin-C-glycoside. |
| PubMed: | LC determination and pharmacokinetic study of the main phenolic components of Portulaca oleracea L. extract in rat plasma after oral administration. |
| PubMed: | Simultaneous determination of three polyphenols in rat plasma after orally administering hawthorn leaves extract by the HPLC method. |
| PubMed: | HPLC determination of five polyphenols in rat plasma after intravenous administration of hawthorn leaves extract and its application to pharmacokinetic study. |
| PubMed: | Simultaneous determination of vitexin-4''-O-glucoside, vitexin-2''-O-rhamnoside, rutin and vitexin from hawthorn leaves flavonoids in rat plasma by UPLC-ESI-MS/MS. |
| PubMed: | The pharmacokinetics of C-glycosyl flavones of Hawthorn leaf flavonoids in rat after single dose oral administration. |
| PubMed: | [DPPH radical scavenging activities of 31 flavonoids and phenolic acids and 10 extracts of Chinese materia medica]. |
| PubMed: | Screening and structural characterization of alpha-glucosidase inhibitors from hawthorn leaf flavonoids extract by ultrafiltration LC-DAD-MS(n) and SORI-CID FTICR MS. |
| PubMed: | HPLC determination of eight polyphenols in the leaves of Crataegus pinnatifida Bge. var. major. |
| PubMed: | Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2''-O-rhamnoside from Crataegus monogyna Jacq. (hawthorn). |
| PubMed: | Assessment of intestinal absorption of vitexin-2''-o-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models. |
| PubMed: | 4'''-Acetylvitexin-2''-O-rhamnoside, isoorientin, orientin, and 8-methoxykaempferol-3-O-glucoside as markers for the differentiation of Crataegus monogyna and Crataegus pentagyna from Crataegus laevigata (Rosaceae). |
| PubMed: | Determination of vitexin-2''-O-rhamnoside in rat plasma by ultra-performance liquid chromatography electrospray ionization tandem mass spectrometry and its application to pharmacokinetic study. |
| PubMed: | Simultaneous determination of vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn (Crataegus pinnatifida Bge.) leaves by RP-HPLC with ultraviolet photodiode array detection. |
| PubMed: | High-performance liquid chromatographic determination and pharmacokinetic study of vitexin-2''-O-rhamnoside in rat plasma after intravenous administration. |
| PubMed: | Evaluation of the content and stability of the constituents of mother tinctures and tinctures: the case of Crataegus oxyacantha L. and Hieracium pilosella L. |
| PubMed: | Simultaneous determination of vitexin-4''-O-glucoside and vitexin-2''-O-rhamnoside from Hawthorn leaves flavonoids in rat plasma by HPLC method and its application to pharmacokinetic studies. |
| PubMed: | Chemosystematic value of flavonoids from Crataegus x macrocarpa (Rosaceae) with special emphasis on (R)- and (S)-eriodictyol-7-O-glucuronide and luteolin-7-O-glucuronide. |
| PubMed: | [Study on the chemical constituents of the leaves from Crataegus pinnatifida Bge. var. major N. E. Br]. |
| PubMed: | Characterization and biological activity of the main flavonoids from Swiss Chard (Beta vulgaris subspecies cycla). |
| PubMed: | Applied environmental stresses to enhance the levels of polyphenolics in leaves of hawthorn plants. |
| PubMed: | On-line coupling of capillary isotachophoresis and zone electrophoresis for the assay of phenolic compounds in plant extracts. |
| PubMed: | Production of Flavonoids in Cell Cultures of Crataegus monogyna. |
| PubMed: | Antihepatotoxic C-glycosylflavones from the leaves of Allophyllus edulis var. edulis and gracilis. |
| PubMed: | Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine: vitexin 2"-O-rhamnoside 7-O-methyltransferase of Avena sativa L. |
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