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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 487.40 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 368.00 °F. TCC ( 186.80 °C. ) (est)
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| logP (o/w): | 3.130 (est) |
| Soluble in: |
| | water, 34.13 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for tectochrysin usage levels up to: | | | not for fragrance use.
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| Recommendation for tectochrysin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4H-1- | benzopyran-4-one, 5-hydroxy-7-methoxy-2-phenyl- (9CI) | | | flavone, 5-hydroxy-7-methoxy- (8CI) | | 5- | hydroxy-7-methoxy-2-phenylchromen-4-one | | 5- | hydroxy-7-methoxyflavone | | | methyl chrysin |
Articles:
| PubMed: | Modulation of (-)-epicatechin Metabolism by Co-administration with other Polyphenols in Caco-2 Cell Model. |
| PubMed: | Anti-cancer effect of tectochrysin in NSCLC cells through overexpression of death receptor and inactivation of STAT3. |
| PubMed: | [Chemical constituents of leaves of Psidium guajava]. |
| PubMed: | Identification of known chemicals and their metabolites from Alpinia oxyphylla fruit extract in rat plasma using liquid chromatography/tandem mass spectrometry (LC-MS/MS) with selected reaction monitoring. |
| PubMed: | Different accumulation profiles of multiple components between pericarp and seed of Alpinia oxyphylla capsular fruit as determined by UFLC-MS/MS. |
| PubMed: | Two new antioxidant diarylheptanoids from the fruits of Alpinia oxyphylla. |
| PubMed: | Anti-diarrheal constituents of Alpinia oxyphylla. |
| PubMed: | Nocapyrones H-J, 3,6-disubstituted α-pyrones from the marine actinomycete Nocardiopsis sp. KMF-001. |
| PubMed: | Two new natural products from the fruits of Alpinia oxyphylla with inhibitory effects on nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophage cells. |
| PubMed: | Antitumor constituents from the leaves of Carya cathayensis. |
| PubMed: | Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin. |
| PubMed: | Aryl hydrocarbon receptor ligand activity of commercial health foods. |
| PubMed: | Chemical composition of the ethanolic propolis extracts and its effect on HeLa cells. |
| PubMed: | Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids. |
| PubMed: | [Chemical constituents from seeds of Alpinia katsumadai, inhibition on NF-kappaB activation and anti-tumor effect]. |
| PubMed: | [Chemical constituents of roots of Saposhnikovia divaricata]. |
| PubMed: | Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells. |
| PubMed: | Bioactivity of flavonoids isolated from Lychnophora markgravii against Leishmania amazonensis amastigotes. |
| PubMed: | [Studies on chemical constituents in fruit of Alpinia oxyphylla]. |
| PubMed: | Simultaneous quantification of eight major bioactive phenolic compounds in Chinese propolis by high-performance liquid chromatography. |
| PubMed: | Main flavonoids, DPPH activity, and metal content allow determination of the geographical origin of propolis from the Province of San Juan (Argentina). |
| PubMed: | [Studies on ethyl acetate soluble constituents of Huanglian Jiedutang]. |
| PubMed: | Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse. |
| PubMed: | Hexaquacobalt(II) bis(5-hydroxy-7-methoxy-4-oxo-2-phenyl-4H-chromene-6-sulfonate) tetrahydrate. |
| PubMed: | Influence of some bioflavonoids on the transport of nitrendipine. |
| PubMed: | Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones. |
| PubMed: | Gateways to clinical trials. |
| PubMed: | Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells. |
| PubMed: | Effect of different flavonoids on collagen synthesis in human fibroblasts. |
| PubMed: | Biflavonoids from Lonicera japonica. |
| PubMed: | Evaluation of the main contact allergens in propolis (1995 to 2005). |
| PubMed: | Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. |
| PubMed: | Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures. |
| PubMed: | Effects of the dietary flavonoid chrysin in isolated rat mesenteric vascular bed. |
| PubMed: | Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells. |
| PubMed: | Identification of metabolites in plasma and urine of Uruguayan propolis-treated rats. |
| PubMed: | Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta. |
| PubMed: | Trypanocidal activity of Lychnophora staavioides Mart. (Vernonieae, Asteraceae). |
| PubMed: | Quantification of 6-deoxy-6-demethyl-4-dedimethylaminotetracycline (COL-3) in human plasma using liquid chromatography coupled with electrospray ionization tandem mass spectrometry. |
| PubMed: | Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells. |
| PubMed: | In vivo anti-oxidant activities of tectochrysin. |
| PubMed: | [Flavonoids from Beijing propolis]. |
| PubMed: | Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements. |
| PubMed: | Vasorelaxant effects of the bioflavonoid chrysin in isolated rat aorta. |
| PubMed: | Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation. |
| PubMed: | Identification of kaempferol as a monoamine oxidase inhibitor and potential Neuroprotectant in extracts of Ginkgo biloba leaves. |
| PubMed: | Differential effects of dietary flavonoids on drug metabolizing and antioxidant enzymes in female rat. |
| PubMed: | Separation of structurally related flavonoids by GC/MS technique and determination of their polarographic parameters and potential carcinogenicity. |
| PubMed: | A novel 2-hydroxyflavanone from collinsonia canadensis |
| PubMed: | Methyl 4-hydroxy-3-(3'-methyl-2'-butenyl)benzoate, major insecticidal principle from Piper guanacastensis. |
| PubMed: | Redox intermediates of flavonoids and caffeic acid esters from propolis: an EPR spectroscopy and cyclic voltammetry study. |
| PubMed: | Antimutagenic effect of plant flavonoids in the Salmonella assay system. |
| PubMed: | Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. |
| PubMed: | Isolation of potential cancer chemopreventive agents from Eriodictyon californicum. |
| PubMed: | Leaf Gland Flavonoids in Comptonia peregrina and Myrica pensylvanica (Myricaceae). |
| PubMed: | Metabolism of apigenin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro. |
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