penconazole
1H-1,2,4-triazole, 1-[2-(2,4-dichlorophenyl)pentyl]-
 
Notes:
None found
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CAS Number: 66246-88-6Picture of molecule3D/inchi
Other(deleted CASRN): 87501-25-5
ECHA EINECS - REACH Pre-Reg: 266-275-6
FDA UNII: 3UN9F9ZJ43
Nikkaji Web: J243.083E
Beilstein Number: 0541488
MDL: MFCD00078737
XlogP3-AA: 4.40 (est)
Molecular Weight: 284.18755000
Formula: C13 H15 Cl2 N3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 58.50 °C. @ 760.00 mm Hg
Boiling Point: 415.30 °C. @ 760.00 mm Hg (est)
Flash Point: 401.00 °F. TCC ( 204.90 °C. ) (est)
logP (o/w): 3.660 (est)
Soluble in:
 water, 73 mg/L @ 20 °C (exp)
 water, 1.547 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Sigma-Aldrich
For experimental / research use only.
Penconazole PESTANAL®, analytical standard
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50  2444 mg/kg
Defense des Vegetaux. Vol. 38, Pg. 195, 1984.

oral-rat LD50  2125 mg/kg
Pesticide Manual. Vol. 9, Pg. 554, 1991.

Dermal Toxicity:
skin-rat LD50 > 3000 mg/kg
Defense des Vegetaux. Vol. 38, Pg. 195, 1984.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for penconazole usage levels up to:
 not for fragrance use.
 
Recommendation for penconazole flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the setting of new MRLs for penconazole in blackberries and raspberries
View page or View pdf
Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
Modification of the existing maximum residue level for penconazole in grapes
View page or View pdf
Review of the existing maximum residue levels for penconazole according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 91693
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 1-[2-(2,4-dichlorophenyl)pentyl]-1,2,4-triazole
Chemidplus: 0066246886
RTECS: XZ4615000 for cas# 66246-88-6
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References:
 1-[2-(2,4-dichlorophenyl)pentyl]-1,2,4-triazole
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 91693
Pubchem (sid): 135048273
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C18801
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
1-(2,4-dichloro-b-propylphenethyl)-1H-1,2,4-triazole
1-[2-(2,4-dichlorophenyl)-n-pentyl]-1H-1,2,4-triazole
1-[2-(2,4-dichlorophenyl)pentyl]-1,2,4-triazole
1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole
 penconazole [BSI] [ISO]
1-[2--N-pentyl]-1H-1,2,4-triazole
 topas 100
 topas C
 topas MZ
 topaze C
1H-1,2,4-triazole, 1-[2-(2,4-dichlorophenyl)pentyl]-
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Articles:
PubMed: Does fungicide application in vineyards induce resistance to medical azoles in Aspergillus species?
PubMed: Development of a new microextraction method based on elevated temperature dispersive liquid-liquid microextraction for determination of triazole pesticides residues in honey by gas chromatography-nitrogen phosphorus detection.
PubMed: Resilience of the natural phyllosphere microbiota of the grapevine to chemical and biological pesticides.
PubMed: Penconazole induced changes in photosynthesis, ion acquisition and protein profile of Mentha pulegium L. under drought stress.
PubMed: Dermal & inhalation exposure of operators during fungicide application in vineyards. Evaluation of coverall performance.
PubMed: Environmental monitoring of pesticide residues from farms at a neighbouring primary and pre-school in the Western Cape in South Africa.
PubMed: Preparation and application of a polythiophene solid-phase microextraction fiber for the determination of endocrine-disruptor pesticides in well waters.
PubMed: Processing factor for a selected group of pesticides in a wine-making process: distribution of pesticides during grape processing.
PubMed: Probing the molecular interaction of triazole fungicides with human serum albumin by multispectroscopic techniques and molecular modeling.
PubMed: Effect of organic matter and pH on the adsorption of metalaxyl and penconazole by soils.
PubMed: Cancer-related genes transcriptionally induced by the fungicide penconazole.
PubMed: A new chiral residue analysis method for triazole fungicides in water using dispersive liquid-liquid microextraction (DLLME).
PubMed: Preparation and characterization of sodium dodecyl sulfate doped polypyrrole solid phase micro extraction fiber and its application to endocrine disruptor pesticide analysis.
PubMed: Comparison of air-agitated liquid-liquid microextraction technique and conventional dispersive liquid-liquid micro-extraction for determination of triazole pesticides in aqueous samples by gas chromatography with flame ionization detection.
PubMed: [Toxic hepatitis after intake of raspberries].
PubMed: Assessment of DFG-S19 method for the determination of common endocrine disruptor pesticides in wine samples with an estimation of the uncertainty of the analytical results.
PubMed: Dissipation of penconazole in peach, plum, apricot, and mango by HPLC-DAD.
PubMed: Comparison of four extraction methods for the determination of fungicide residues in grapes through gas chromatography-mass spectrometry.
PubMed: Comparison of the selectivity of different sorbent phases for bar adsorptive microextraction--application to trace level analysis of fungicides in real matrices.
PubMed: Planar solid phase extraction clean-up for pesticide residue analysis in tea by liquid chromatography-mass spectrometry.
PubMed: Three years monitoring survey of pesticide residues in Sardinia wines following integrated pest management strategies.
PubMed: The dissipation of three fungicides in a biobed organic substrate and their impact on the structure and activity of the microbial community.
PubMed: The influence of fining agents on the removal of some pesticides from white wine of Vitis vinifera L. cv. Emir.
PubMed: Dissipation of penconazole in tomatoes and soil.
PubMed: Dissipation of fungicides in a vineyard soil amended with different spent mushroom substrates.
PubMed: [Determination of 11 triazole fungicides in fruits using solid phase extraction and gas chromatography-tandem mass spectrometry].
PubMed: Impact of fungicides on the diversity and function of non-target ammonia-oxidizing microorganisms residing in a litter soil cover.
PubMed: Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight.
PubMed: A non-destructive method for testing two components of the behaviour of soil-applied agricultural chemicals over a long period.
PubMed: Combination of solid-phase extraction-hollow fiber for ultra-preconcentration of some triazole pesticides followed by gas chromatography-flame ionization detection.
PubMed: Biological monitoring of pesticide exposures in residents living near agricultural land.
PubMed: Losses and dissipation of penconazole in vineyard soil as affected by mid-row management system.
PubMed: Enantiomeric separation of triazole fungicides with 3-μm and 5-μml particle chiral columns by reverse-phase high-performance liquid chromatography.
PubMed: Determination of 40 currently used pesticides in airborne particulate matter (PM 10) by microwave-assisted extraction and gas chromatography coupled to triple quadrupole mass spectrometry.
PubMed: Extraction and preconcentration technique for triazole pesticides from cow milk using dispersive liquid-liquid microextraction followed by GC-FID and GC-MS determinations.
PubMed: Pesticide removal from waste spray-tank water by organoclay adsorption after field application to vineyards.
PubMed: Reducing the impact of pesticides on biological control in Australian vineyards: pesticide mortality and fecundity effects on an indicator species, the predatory mite Euseius victoriensis (Acari: Phytoseiidae).
PubMed: Determination of fungicides in wine by mixed-mode solid phase extraction and liquid chromatography coupled to tandem mass spectrometry.
PubMed: Sorption of penconazole applied as a commercial water-oil emulsion in soils devoted to vineyards.
PubMed: Effect of spent mushroom substrate amendment of vineyard soils on the behavior of fungicides: 2. Mobility of penconazole and metalaxyl in undisturbed soil cores.
PubMed: Coupling stir bar sorptive extraction-dispersive liquid-liquid microextraction for preconcentration of triazole pesticides from aqueous samples followed by GC-FID and GC-MS determinations.
PubMed: Retention capacity of an organic bio-mixture against different mixtures of fungicides used in vineyards.
PubMed: Adsorption of chlorpyrifos, penconazole and metalaxyl from aqueous solution by modified clays.
PubMed: Development of immunoassays for the detection of the fungicide penconazole and its urinary metabolite.
PubMed: Effect of spent mushroom substrate amendment of vineyard soils on the behavior of fungicides: 1. Adsorption-desorption of penconazole and metalaxyl by soils and subsoils.
PubMed: Dissipation of profenofos, imidacloprid and penconazole in tomato fruits and products.
PubMed: Sensitivity of Podosphaera aphanis isolates to DMI fungicides: distribution and reduced cross-sensitivity.
PubMed: Fate and distribution of pyrimethanil, metalaxyl, dichlofluanid and penconazol fungicides from treated grapes intended for winemaking.
PubMed: Solid-phase extraction followed by dispersive liquid-liquid microextraction for the sensitive determination of selected fungicides in wine.
PubMed: Toxicity of triclosan, penconazole and metalaxyl on Caulobacter crescentus and a freshwater microbial community as assessed by flow cytometry.
PubMed: Effect of fungicides and of biocontrol agents against powdery mildew of turnip.
PubMed: Cyclodextrin-modified MEKC for enantioseparation of hexaconazole, penconazole, and myclobutanil.
PubMed: 1-[2-(2,4-Dichloro-phenyl)-pent-yl]-1H-1,2,4-triazole.
PubMed: Development of monoclonal immunoassays for the determination of triazole fungicides in fruit juices.
PubMed: Effect of biocompost-amendment on degradation of triazoles fungicides in soil.
PubMed: Triazole induced drought tolerance in horse chestnut (Aesculus hippocastanum).
PubMed: Significance of the long-chain organic cation structure in the sorption of the penconazole and metalaxyl fungicides by organo clays.
PubMed: Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants.
PubMed: Pesticide analysis in tomatoes by solid-phase microextraction and micellar electrokinetic chromatography.
PubMed: Pesticide analysis in rose wines by micellar electrokinetic chromatography.
PubMed: Multiple pesticide analysis in wine by MEKC combined with solid-phase microextraction and sample stacking.
PubMed: Seasonal distributions of fungicides in soils and sediments of a small river basin partially devoted to vineyards.
PubMed: Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues.
PubMed: MEKC combined with SPE and sample stacking for multiple analysis of pesticides in water samples at the ng/L level.
PubMed: Bioaccumulation and biotransformation of chiral triazole fungicides in rainbow trout (Oncorhynchus mykiss).
PubMed: Influence of pH and soil copper on adsorption of metalaxyl and penconazole by the surface layer of vineyard soils.
PubMed: Impact of fungicides on Aspergillus carbonarius growth and ochratoxin A production on synthetic grape-like medium and on grapes.
PubMed: Effects of penconazole on two yeast strains: growth kinetics and molecular studies.
PubMed: Quantitation of 13 azole fungicides in wine samples by liquid chromatography-tandem mass spectrometry.
PubMed: Pesticide residues survey in citrus fruits.
PubMed: Mobility of four triazole fungicides in two Indian soils.
PubMed: Parameters affecting extraction of selected fungicides from vineyard soils.
PubMed: Evaluation of a method based on liquid chromatography/electrospray tandem mass spectrometry for analyzing eight triazolic and pyrimidine fungicides in extracts of processed fruits and vegetables.
PubMed: Presence of plant protection products in three agricultural areas of Regione Lazio.
PubMed: Effect of the addition of wine distillery wastes to vineyard soils on the adsorption and mobility of fungicides.
PubMed: Multiresidue method using SPME for the determination of various pesticides with different volatility in confined atmospheres.
PubMed: Coupling solid-phase microextraction and high-performance liquid chromatography for direct and sensitive determination of halogenated fungicides in wine.
PubMed: Triazole fungicide degradation in peaches in the field and in model systems.
PubMed: Contamination of rural surface and ground water by endosulfan in farming areas of the Western Cape, South Africa.
PubMed: Solid-phase microextraction and gas chromatography-mass spectrometry for the rapid screening of triazole residues in wine and strawberries.
PubMed: Influence of different mineral and Organic pesticide treatments on Cd(II), Cu(II), Pb(II), and Zn(II) contents determined by derivative potentiometric stripping analysis in Italian white and red wines.
PubMed: Sorption behavior of triazole fungicides in Indian soils and its correlation with soil properties.
PubMed: Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells.
PubMed: Monitoring of pesticide residues on cucumber, tomatoes and strawberries in Gaza Governorates, Palestine.
PubMed: Determination of penconazole on personal protection equipment after field applications.
PubMed: Development of a SPME-GC-ECD methodology for selected pesticides in must and wine samples.
PubMed: High-performance chiral separation of fourteen triazole fungicides by sulfated beta-cyclodextrin-mediated capillary electrophoresis.
PubMed: Yeasts as a model for assessing the toxicity of the fungicides Penconazol, Cymoxanil and Dichlofluanid.
PubMed: Evolution of chlorpyrifos, fenarimol, metalaxyl, penconazole, and vinclozolin in red wines elaborated by carbonic maceration of Monastrell grapes.
PubMed: Application of liquid chromatography with mass spectrometry combined with photodiode array detection and tandem mass spectrometry for monitoring pesticides in surface waters.
PubMed: Pesticide residues in grapes, wine, and their processing products.
PubMed: Investigation on fungicide residues in greenhouse-grown strawberries.
PubMed: Rapid detection of efflux pumps and their relation with drug resistance in yeast cells.
PubMed: Effect of pesticide residues on the aromatic composition of red wines.
PubMed: Evolution of residual levels of six pesticides during elaboration of red wines. Effect of wine-making procedures in their dissappearance.
PubMed: Multiresidue determination of 19 fungicides in processed fruits and vegetables by capillary gas chromatography after gel permeation chromatography.
PubMed: Solid phase microextraction of pesticide residues from strawberries.
PubMed: Determination of chlorpyrifos, penconazole, fenarimol, vinclozolin and metalaxyl in grapes, must and wine by on-line microextraction and gas chromatography.
PubMed: Evidence for and characterization of cytochrome P-450 in Neurospora crassa.
PubMed: An Ustilago maydis Mutant Partially Blocked in P45014DM Activity Is Hypersensitive to Azole Fungicides
PubMed: The study of interactive effects of pollutants: a biomarker approach.
PubMed: Fungicides and photochemistry: photodegradation of the azole fungicide penconazole.
PubMed: Endogenous promutagen activation in the yeast Saccharomyces cerevisiae: factors influencing aflatoxin B1 mutagenicity.
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