fenhexamid
cyclohexanecarboxamide, N-(2,3-dichloro-4-hydroxyphenyl)-1-methyl-
 
Notes:
None found
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CAS Number: 126833-17-8Picture of molecule3D/inchi
FDA UNII: Q68C3C9P1U
Nikkaji Web: J1.063.660D
Beilstein Number: 8996658
MDL: MFCD03095700
XlogP3-AA: 4.40 (est)
Molecular Weight: 302.19889000
Formula: C14 H17 Cl2 N O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: white powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 457.90 °C. @ 760.00 mm Hg (est)
Flash Point: 447.00 °F. TCC ( 230.70 °C. ) (est)
logP (o/w): 4.020 (est)
Soluble in:
 water, 11.99 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
Fenhexamid
Sigma-Aldrich
For experimental / research use only.
Fenhexamid PESTANAL®, analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for fenhexamid usage levels up to:
 not for fragrance use.
 
Recommendation for fenhexamid flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the review of the existing maximum residue levels (MRLs) for fenhexamid according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid
View page or View pdf
Reasoned opinion on the modification of the MRLs for fenhexamid in various berries
View page or View pdf
Modification of the existing maximum residue levels for fenhexamid in various crops
View page or View pdf
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 213031
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide
Chemidplus: 0126833178
RTECS: GU7879550 for cas# 126833-17-8
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References:
 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 213031
Pubchem (sid): 135187461
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C18593
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•trade names: decree, elevate, teldor •suspension concentrate, water dispersible granule, wettable powder. •mixtures: talat (+tolylfluanid); young-gune (+tebuconazole) (spray, korea). •the end-use product (elevate 50 wdg) is a water dispersible granule formulation containing 50% active ingredient.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 cyclohexanecarboxamide, N-(2,3-dichloro-4-hydroxyphenyl)-1-methyl-
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide
 KBR-2738
 KBR2738
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Articles:
PubMed: Fungicide resistance of Botrytis cinerea in tomato greenhouses in the Canary Islands and effectiveness of non-chemical treatments against gray mold.
PubMed: Genetic diversity in Monilinia laxa populations in stone fruit species in Hungary.
PubMed: Morphological and phylogenetic identification of Botrytis sinoviticola, a novel cryptic species causing gray mold disease of table grapes (Vitis vinifera) in China.
PubMed: Occurrence of fungicide resistance in populations of Botryotinia fuckeliana (Botrytis cinerea) on table grape and strawberry in southern Italy.
PubMed: Influence of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation and aroma biosynthesis.
PubMed: Metabolomic approach assisted high resolution LC-ESI-MS based identification of a xenobiotic derivative of fenhexamid produced by Lactobacillus casei.
PubMed: Toxic responses and antioxidative enzymes activity of Scenedesmus obliquus exposed to fenhexamid and atrazine, alone and in mixture.
PubMed: Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor.
PubMed: Assessment of silicone as support to investigate the transformation routes of organic chemicals under environmental conditions and UV exposure. Application to selected fungicides.
PubMed: Liquid chromatography time-of-flight mass spectrometry evaluation of fungicides reactivity in free chlorine containing water samples.
PubMed: A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET.
PubMed: Role of sterol 3-ketoreductase sensitivity in susceptibility to the fungicide fenhexamid in Botrytis cinerea and other phytopathogenic fungi.
PubMed: Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells.
PubMed: Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides.
PubMed: Retrospective screening of relevant pesticide metabolites in food using liquid chromatography high resolution mass spectrometry and accurate-mass databases of parent molecules and diagnostic fragment ions.
PubMed: Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
PubMed: The allele-specific probe and primer amplification assay, a new real-time PCR method for fine quantification of single-nucleotide polymorphisms in pooled DNA.
PubMed: Genetic diversity of a Botrytis cinerea cryptic species complex in Hungary.
PubMed: Determination of famoxadone, fenamidone, fenhexamid and iprodione residues in greenhouse tomatoes.
PubMed: Strong resistance to the fungicide fenhexamid entails a fitness cost in Botrytis cinerea, as shown by comparisons of isogenic strains.
PubMed: Remediation of fungicide residues on fresh produce by use of gaseous ozone.
PubMed: Use of soft and hard ionization techniques for elucidation of unknown compounds by gas chromatography/time-of-flight mass spectrometry.
PubMed: The sterol biosynthesis inhibitor molecule fenhexamid impacts the vegetative compatibility of Glomus clarum.
PubMed: Glove accumulation of pesticide residues for strawberry harvester exposure assessment.
PubMed: Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens.
PubMed: Photocatalytic degradation of the fungicide Fenhexamid in aqueous TiO(2) suspensions: identification of intermediates products and reaction pathways.
PubMed: Fenpropimorph and fenhexamid impact phosphorus translocation by arbuscular mycorrhizal fungi.
PubMed: Photochemical analysis of 14C-fenhexamid in aqueous solution and structural elucidation of a new metabolite.
PubMed: Multiple resistance of Botrytis cinerea from kiwifruit to SDHIs, QoIs and fungicides of other chemical groups.
PubMed: Influence of several fungicides on the antioxidant activity of red wines (var. Monastrell).
PubMed: Multi-residue analysis of 30 currently used pesticides in fine airborne particulate matter (PM 2.5) by microwave-assisted extraction and liquid chromatography-tandem mass spectrometry.
PubMed: Chemometric study and optimization of extraction parameters in single-drop microextraction for the determination of multiclass pesticide residues in grapes and apples by gas chromatography mass spectrometry.
PubMed: Arbuscular mycorrhiza partially protect chicory roots against oxidative stress induced by two fungicides, fenpropimorph and fenhexamid.
PubMed: Monoclonal antibody generation and direct competitive enzyme-linked immunosorbent assay evaluation for the analysis of the fungicide fenhexamid in must and wine.
PubMed: Multiresidue pesticide analysis of wines by dispersive solid-phase extraction and ultrahigh-performance liquid chromatography-tandem mass spectrometry.
PubMed: Effectiveness of control strategies against Botrytis cinerea in vineyard and evaluation of the residual fungicide concentrations.
PubMed: Removal of fenhexamid and pyrimethanil from aqueous solutions by clays and organoclays.
PubMed: Differential effects of fenpropimorph and fenhexamid, two sterol biosynthesis inhibitor fungicides, on arbuscular mycorrhizal development and sterol metabolism in carrot roots.
PubMed: Botryticides affect grapevine leaf photosynthesis without inducing defense mechanisms.
PubMed: Fenhexamid adsorption behavior on soil amended with wine lees.
PubMed: Toxicity of six novel fungicides and sulphur to Galendromus occidentalis (Acari: Phytoseiidae).
PubMed: Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
PubMed: Effect of the use of recent commercial fungicides [under good and critical agricultural practices] on the aroma composition of Monastrell red wines.
PubMed: Influence of fungicides on grape yeast content and its evolution in the fermentation.
PubMed: Effects of two sterol biosynthesis inhibitor fungicides (fenpropimorph and fenhexamid) on the development of an arbuscular mycorrhizal fungus.
PubMed: Behavior of fenhexamid in soil and water.
PubMed: Evaluation of solid sorbents for the determination of fenhexamid, metalaxyl-M, pyrimethanil, malathion and myclobutanil residues in air samples: application to monitoring malathion and fenhexamid dissipation in greenhouse air using C-18 or Supelpak-2 for sampling.
PubMed: Disappearance of fenhexamid residues during wine-making process.
PubMed: Impact of fungicides on Aspergillus carbonarius growth and ochratoxin A production on synthetic grape-like medium and on grapes.
PubMed: Rapid gas chromatographic method for the determination of famoxadone, trifloxystrobin and fenhexamid residues in tomato, grape and wine samples.
PubMed: Determination of fungicide residues in field-grown strawberries following different fungicide strategies against gray mold (Botrytis cinerea).
PubMed: Residues of azoxystrobin, fenhexamid and pyrimethanil in strawberry following field treatments and the effect of domestic washing.
PubMed: Metallothionein induction, antioxidative responses, glycogen and growth changes in Tubifex tubifex (Oligochaete) exposed to the fungicide, fenhexamid.
PubMed: Behavior of a fenhexamid photoproduct during the alcoholic fermentation of Saccharomyces cerevisiae.
PubMed: Activity of some chemicals in the control of Botrytis cinerea on roses.
PubMed: Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.
PubMed: Analysis of fenhexamid in caneberry, blueberry, and pomegranate by liquid chromatography-tandem mass spectrometry.
PubMed: Processing factors and variability of pyrimethanil, fenhexamid and tolylfluanid in strawberries.
PubMed: Interaction between fenhexamid and yeasts during the alcoholic fermentation of Saccharomyces cerevisiae.
PubMed: Characterization of Bc-hch, the Botrytis cinerea homolog of the Neurospora crassahet-c vegetative incompatibility locus, and its use as a population marker.
PubMed: Mechanisms of resistance to fungicides in field strains of Botrytis cinerea.
PubMed: The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea).
PubMed: Fenhexamid residues in grapes and wine.
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