| PubMed: | [Jatropha seed oils extracted by different methods and their effect on killing cercaria of Schistosoma japonicum]. |
| PubMed: | AzoneĀ® decreases the buccal mucosal permeation of diazepam in a concentration-dependent manner via a reservoir effect. |
| PubMed: | Development of a doxazosin and finasteride transdermal system for combination therapy of benign prostatic hyperplasia. |
| PubMed: | Evaluation of percutaneous absorption of esculetin: effect of chemical enhancers. |
| PubMed: | Azone analogues: classification, design, and transdermal penetration principles. |
| PubMed: | Effect of soybean-lecithin as an enhancer of buccal mucosa absorption of insulin. |
| PubMed: | Transdermal absorption of memantin--effect of chemical enhancers, iontophoresis, and role of enhancer lipophilicity. |
| PubMed: | [Influence of penetration enhancers on in vitro transdermal permeation of L-tethrahydropalmatine]. |
| PubMed: | Transdermal and transbuccal drug delivery systems: enhancement using iontophoretic and chemical approaches. |
| PubMed: | Preparation and evaluation of 5, 9-dimethyl-2-cyclopropyl-2-decanol as a penetration enhancer for drugs through rat skin. |
| PubMed: | Investigation of microemulsion microstructures and their relationship to transdermal permeation of model drugs: ketoprofen, lidocaine, and caffeine. |
| PubMed: | Corneal permeability assay of topical eye drop solutions in rabbits by MRI. |
| PubMed: | Enhanced in vitro transbuccal drug delivery of ondansetron HCl. |
| PubMed: | Topical drug delivery by a polymeric nanosphere gel: Formulation optimization and in vitro and in vivo skin distribution studies. |
| PubMed: | The buccal mucosa as an alternative route for the systemic delivery of risperidone. |
| PubMed: | Combined strategies for enhancing the transdermal absorption of midazolam through human skin. |
| PubMed: | Percutaneous penetration modifiers and formulation effects: thermal and spectral analyses. |
| PubMed: | Development and evaluation of occlusive systems employing polyvinyl alcohol for transdermal delivery of sumatriptan succinate. |
| PubMed: | Percutaneous penetration modifiers and formulation effects. |
| PubMed: | Effect of counter-ions and penetration enhancers on the skin permeation of flurbiprofen. |
| PubMed: | Chemical penetration enhancers: a patent review. |
| PubMed: | Mechanical and baicalin delivery properties of adhesive matrices for iontophoretic flexible electrodes. |
| PubMed: | [Effects of penetration enhancers on percutaneous permeability of geniposide in Xiao'er Ninhuang tuire cataplasms]. |
| PubMed: | Effect of ion-pairing and enhancers on scutellarin skin permeability. |
| PubMed: | Enhancement of nortriptyline penetration through human epidermis: influence of chemical enhancers and iontophoresis. |
| PubMed: | Transdermal permeation enhancement of N-trimethyl chitosan for testosterone. |
| PubMed: | [Preparation of transdermal drug delivery system of felodipine-metoprolol and its bioavailability in rabbits]. |
| PubMed: | Sumatriptan succinate transdermal delivery systems for the treatment of migraine. |
| PubMed: | In vitro studies on transdermal permeation of butorphanol. |
| PubMed: | [Influence of permeation enhancers on transdermal permeation of anemonin]. |
| PubMed: | Simultaneous measurements of K+ and calcein release from liposomes and the determination of pore size formed in a membrane. |
| PubMed: | Investigation into the potential of low-frequency ultrasound facilitated topical delivery of Cyclosporin A. |
| PubMed: | [Corneal permeability of topically applied pirenzepine solution]. |
| PubMed: | Combination strategies for enhancing transdermal absorption of sumatriptan through skin. |
| PubMed: | Pretreatment of plantar warts with azone enhances the effect of 5-aminolevulinic acid photodynamic therapy. |
| PubMed: | Chemical enhancers for the absorption of substances through the skin: Laurocapram and its derivatives. |
| PubMed: | In vivo skin permeation of sodium naproxen formulated in pluronic F-127 gels: effect of Azone and Transcutol. |
| PubMed: | [Effects of different penetration enhancers on percutaneous absorption of lappaconitine gel in vitro]. |
| PubMed: | Interaction of 1-dodecyl-azacycloheptan-2-one with mouse stratum corneum. |
| PubMed: | Enhancing the buccal mucosal uptake and retention of triamcinolone acetonide. |
| PubMed: | Effects of ionization and penetration enhancers on the transdermal delivery of 5-fluorouracil through excised human stratum corneum. |
| PubMed: | Enhanced buccal mucosal retention and reduced buccal permeability of estradiol in the presence of padimate O and Azone: a mechanistic study. |
| PubMed: | [Synthetical evaluation of promoting effect of some kinds of transdermal enhancers with grey relational cluster method]. |
| PubMed: | In vitro release study of transdermal delivery systems of progesterone. |
| PubMed: | [Evaluation of a compound with dan-shen root and azone for scar treatment]. |
| PubMed: | Development and in vitro evaluation of furosemide transdermal formulations using experimental design techniques. |
| PubMed: | Penetration enhancers. |
| PubMed: | Gateways to clinical trials. |
| PubMed: | Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers. |
| PubMed: | L-Serine and glycine based ceramide analogues as transdermal permeation enhancers: polar head size and hydrogen bonding. |
| PubMed: | Phase 1/2 pilot study of methotrexate-laurocapram topical gel for the treatment of patients with early-stage mycosis fungoides. |
| PubMed: | In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug. |
| PubMed: | [Transdermal delivery of diclofenac sodium gel after iontophoresis] |
| PubMed: | Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice. |
| PubMed: | [Effects of Azone of different concentrations on percutaneous absorption of baicalin in vitro]. |
| PubMed: | [Promotion of ferulic acid transdermal absorption by water-soluble azone in Shengfaling tincture]. |
| PubMed: | Experimental study of in vitro buprenorphine hydrochloride transdermal permeation through hairless mouse skin. |
| PubMed: | [Azone-induced changes on corneal endothelium in rabbits]. |
| PubMed: | [Screening of enhancers for permeation of berberine in ruyi patcher in vitro]. |
| PubMed: | Evaluation of in vitro percutaneous absorption of lorazepam and clonazepam from hydro-alcoholic gel formulations. |
| PubMed: | Passive skin penetration enhancement and its quantification in vitro. |
| PubMed: | Azone enhances clinical effectiveness of an optimized formulation of triamcinolone acetonide in atopic dermatitis. |
| PubMed: | The influence of two azones and sebaceous lipids on the lateral organization of lipids isolated from human stratum corneum. |
| PubMed: | The effect of two azones on the lateral lipid organization of human stratum corneum and its permeability. |
| PubMed: | Transdermal macromolecular delivery: real-time visualization of iontophoretic and chemically enhanced transport using two-photon excitation microscopy. |
| PubMed: | The influence of Span20 on stratum corneum lipids in langmuir monolayers: comparison with Azone. |
| PubMed: | Penetration enhancers assessed by corneoxenometry. |
| PubMed: | Comparative enhancer effects of Span20 with Tween20 and Azone on the in vitro percutaneous penetration of compounds with different lipophilicities. |
| PubMed: | The synergistic effect of laurocapram pretreatment and iontophoresis on the percutaneous permeation of non-steroidal anti-inflammatory drugs in vitro. |
| PubMed: | The skin barrier from a lipid perspective. |
| PubMed: | Transdermal iontophoretic delivery of timolol maleate in albino rabbits. |
| PubMed: | Structure-related aspects on water diffusivity in fatty acid-soap and skin lipid model systems. |
| PubMed: | Synthesis and evaluation of N-acetylprolinate esters - novel skin penetration enhancers. |
| PubMed: | A new computer-based evaporimeter system for rapid and precise measurements of water diffusion through stratum corneum in vitro. |
| PubMed: | Ultrasound-enhanced diffusion into coupling gel during phonophoresis of 5-fluorouracil. |
| PubMed: | The effects of Azone and capsaicin on the permeation of naproxen through human skin. |
| PubMed: | Synthesis and effect of two new penetration enhancers on the transdermal delivery of 5-fluorouracil through excised rat skin. |
| PubMed: | Enhanced skin permeation of sex hormones with novel topical spray vehicles. |
| PubMed: | Phase coexistence in cholesterol-fatty acid mixtures and the effect of the penetration enhancer Azone. |
| PubMed: | Assessment of correlation between skin target site free drug concentration and the in vivo topical antiviral efficacy in hairless mice for (E)-5-(2-bromovinyl)-2'-deoxyuridine and acyclovir formulations. |
| PubMed: | Percutaneous absorption of disopyramide, lidocaine and trimecaine. |
| PubMed: | Effects of penetration enhancers on the in-vitro percutaneous absorption of progesterone. |
| PubMed: | Effect of vehicles and penetration enhancers on the in vitro and in vivo percutaneous absorption of methotrexate and edatrexate through hairless mouse skin. |
| PubMed: | Influences of 1-dodecylazacycloheptan-2-one on permeation of membranes by weak electrolytes. 1. Theoretical analysis of weak electrolyte diffusion through membranes and studies involving silicone rubber membranes. |
| PubMed: | Terbutaline transdermal delivery: preformulation studies and limitations of in-vitro predictive parameters. |
| PubMed: | Modification of macrophage adhesion by ozone: role of cytokines and cell adhesion molecules. |
| PubMed: | Development of a transdermal patch of methadone: in vitro evaluation across hairless mouse and human cadaver skin. |
| PubMed: | Influence of vehicle on patch test response to nickel sulfate. |
| PubMed: | Phase transitions of rat stratum corneum lipids by an electron paramagnetic resonance study and relationship of phase states to drug penetration. |
| PubMed: | Effect of topical laurocapram (Azone) on the in vitro percutaneous permeation of sodium lauryl sulfate using human skin. |
| PubMed: | Microscopic FT-IR/DSC system used to simultaneously investigate the conversion process of protein structure in porcine stratum corneum after pretreatment with skin penetration enhancers. |
| PubMed: | The relative effect of Azone and Transcutol on permeant diffusivity and solubility in human stratum corneum. |
| PubMed: | Transdermal delivery of drugs with differing lipophilicities using azone analogs as dermal penetration enhancers. |
| PubMed: | [The effect of different topical agents on pseudomonas infection of burn wound]. |
| PubMed: | Percutaneous penetration of fluorescein isothiocyanate-dextrans and the mechanism for enhancement effect of enhancers on the intercellular penetration. |
| PubMed: | Role of appendages in skin resistance and iontophoretic peptide flux: human versus snake skin. |
| PubMed: | [Percutaneous absorption of venenum bufonis in vitro]. |
| PubMed: | In vitro percutaneous absorption of arildone, a highly lipophilic drug, and the apparent no-effect of the penetration enhancer Azone in excised human skin. |
| PubMed: | n-pentyl N-acetylprolinate. A new skin penetration enhancer. |
| PubMed: | Effect of various enhancers on transdermal penetration of indomethacin and urea, and relationship between penetration parameters and enhancement factors. |
| PubMed: | Effect of benzyl alcohol on rat skin as a solvent of liquid droplet dispersion ointment. |
| PubMed: | Behavior of propylene glycol (PG) in dermis after treatment of rat intact skin surface with fatty acids, fatty amines or azone dissolved in PG. |
| PubMed: | [Transdermal iontophoresis of insulin: effect of penetration enhancers on blood glucose level in diabetic rats]. |
| PubMed: | Transdermal iontophoresis: effect of penetration enhancer and iontophoresis on drug transport and surface characteristics of human epidermis. |
| PubMed: | Mechanism of the enhancement effect of n-octyl-beta-D-thioglucoside on the transdermal penetration of fluorescein isothiocyanate-labeled dextrans and the molecular weight dependence of water-soluble penetrants through stripped skin. |
| PubMed: | Percutaneous absorption of physiologically active peptides, ebiratide and elcatonin, in rats. |
| PubMed: | Percutaneous absorption of 2',3'-dideoxyinosine in rats. |
| PubMed: | [Influential factors of water evaporation from burn wound]. |
| PubMed: | Percutaneous absorption of azone following single and multiple doses to human volunteers. |
| PubMed: | Effect of some penetration enhancers on epithelial membrane lipid domains: evidence from fluorescence spectroscopy studies. |
| PubMed: | Effects of four penetration enhancers on corneal permeability of drugs in vitro. |
| PubMed: | [An efficacious topical agent--SD-Ag-azone cream]. |
| PubMed: | epsilon-Aminocaproic acid esters as transdermal penetration enhancing agents. |
| PubMed: | Transport of testosterone through rat skin from transdermal patch formulations. |
| PubMed: | [Comparison of therapeutic value of various topical agents in Pseudomonas aeruginosa infection. An experimental study]. |
| PubMed: | Electrochemical characterization of human skin by impedance spectroscopy: the effect of penetration enhancers. |
| PubMed: | Measuring the uptake of Azone into excised human stratum corneum from thin polymer films. |
| PubMed: | Facilitated transport of two model steroids by esters and amides of clofibric acid. |
| PubMed: | Effect of PEG 400, ethanol and laurocapram (Azone) on the transport of testosterone through rat skin. |
| PubMed: | Effects of transdermal penetration enhancers on the permeability of shed snakeskin. |
| PubMed: | Evaluation of a new penetration enhancer 1-[2-(decylthio)ethyl]azacyclopentan-2-one (HPE-101). |
| PubMed: | Enhancement of percutaneous absorption by laurocapram. |
| PubMed: | Comparison of azone and hexamethylene lauramide in toxicologic effects and penetration enhancement of cimetidine in rabbit eyes. |
| PubMed: | Cutaneous metabolism of nitroglycerin in vitro. II. Effects of skin condition and penetration enhancement. |
| PubMed: | Influence of limonene and laurocapram on percutaneous absorption of nonsteroidal anti-inflammatory drugs. |
| PubMed: | Improved transdermal delivery of prostaglandin E1 through hairless mouse skin: combined use of carboxymethyl-ethyl-beta-cyclodextrin and penetration enhancers. |
| PubMed: | Mechanism of skin penetration-enhancing effect by laurocapram. |
| PubMed: | [Transdermal properties of timolol and factors affecting its permeability in vitro]. |
| PubMed: | Preparation of alkyl-substituted pyrrolidone derivatives and their evaluation as transdermal penetration enhancers. |
| PubMed: | Design of 9-beta-D-arabinofuranosyladenine (ara-A) transdermal delivery system for animal studies: regulation of drug concentration in vivo. |
| PubMed: | Dodecyl N,N-dimethylamino acetate and azone enhance drug penetration across human, snake, and rabbit skin. |
| PubMed: | [Effect of enhancers on cutaneous permeation of piroxicam in vitro]. |
| PubMed: | Enhanced skin permeation of papaverine by a medium chain glyceride. |
| PubMed: | Effect of 1-alkyl- or 1-alkenylazacycloalkanone derivatives on the penetration of drugs with different lipophilicities through guinea pig skin. |
| PubMed: | [Research on nifedipine patch]. |
| PubMed: | Enhanced percutaneous absorption of a novel topical cyclosporin A formulation and assessment of its immunosuppressive activity. |
| PubMed: | Use of shed snake skin as a model membrane for in vitro percutaneous penetration studies: comparison with human skin. |
| PubMed: | Effect of cyclic monoterpenes on percutaneous absorption in the case of a water-soluble drug (diclofenac sodium). |
| PubMed: | Percutaneous absorption enhancing effect and skin irritation of monocyclic monoterpenes. |
| PubMed: | Evaluation of in-vitro percutaneous absorption across human skin and in animal models. |
| PubMed: | Transdermal drug delivery: efficacy and potential applications of the penetration enhancer Azone. |
| PubMed: | Effect of monoglycerides on the percutaneous absorption of papaverine hydrochloride. |
| PubMed: | Disposition and metabolic profiling of the penetration enhancer Azone. I. In vitro studies: urinary profiles of hamster, rat, monkey, and man. |
| PubMed: | Enhancing effect of piperidone derivatives on the percutaneous absorption of indomethacin. |
| PubMed: | Percutaneous absorption, metabolic profiling, and excretion of the penetration enhancer azone after multiple dosing of an azone-containing triamcinolone acetonide cream in humans. |
| PubMed: | [Effect of artesunate transdermal preparation on Plasmodium cynomolgi]. |
| PubMed: | [Use of derivative UV spectroscopy to monitor the percutaneous absorption of befunolol-HCL]. |
| PubMed: | Enhancement of hydrocortisone permeation of human and hairless mouse skin by 1-dodecylazacycloheptan-2-one. |
| PubMed: | Dose-dependent enhancement effects of azone on skin permeability. |
| PubMed: | [Influence of laurocapram on ultrastructures of mouse skin and sarcoma 180 membrane]. |
| PubMed: | Variable effects of laurocapram (Azone) on rectal cefoxitin absorption in rats. |
| PubMed: | Effect of limonene and related compounds on the percutaneous absorption of indomethacin. |
| PubMed: | A pharmacokinetic model for the percutaneous absorption of indomethacin and the prediction of drug disposition kinetics. |
| PubMed: | Topical methotrexate therapy for psoriasis. |
| PubMed: | [Continuous effect of azone pretreatment on permeability of antivirotic Ara-ADA through hairless mouse skin]. |
| PubMed: | Utility of topical formulations of morphine hydrochloride containing azone and N-methyl-2-pyrrolidone. |
| PubMed: | Percutaneous absorption enhancer applied to membrane permeation-controlled transdermal delivery of nicardipine hydrochloride. |
| PubMed: | Effect of oleic acid on diffusion of drugs through hairless mouse skin. |
| PubMed: | Corneal endothelial changes with azone, a penetration enhancer. |
| PubMed: | Application of propranolol to the keratinized oral mucosa: avoidance of first-pass elimination and the use of 1-dodecylazacycloheptan-2-one (Azone) as an absorption enhancer of bioadhesive film-dosage form. |
| PubMed: | Thermodynamic study on enhancement of percutaneous penetration of drugs by Azone. |
| PubMed: | Influence of dimethylacetamide, N-N-diethyl-m-toluamide and 1-dodecylazacycloheptan-2-one on ex vivo permeation of phosphonoformic acid through rat skin. |
| PubMed: | Comparison of penetration-enhancing ability of laurocapram, N-methyl-2-pyrrolidone and dodecyl-L-pyroglutamate. |
| PubMed: | Action of penetration enhancers on human skin as assessed by the permeation of model drugs 5-fluorouracil and estradiol. I. Infinite dose technique. |
| PubMed: | Influence of 1-dodecylhexahydro-2H-azepin-2-one (Azone) on the in vitro permeation of verapamil hydrochloride across rat, hairless mouse, and human cadaver skin. |
| PubMed: | Hairless mouse skin is limited as a model for assessing the effects of penetration enhancers in human skin. |
| PubMed: | The effect of azone on ocular levobunolol absorption: calculating the area under the curve and its standard error using tissue sampling compartments. |
| PubMed: | Effects of penetration enhancers on percutaneous absorption of nifedipine. Comparison between Deet and Azone. |
| PubMed: | Topically applied cyclosporine in azone prolongs corneal allograft survival. |
| PubMed: | Transdermal delivery of isoproterenol HCl: an investigation of stability, solubility, partition coefficient, and vehicle effects. |
| PubMed: | Percutaneous absorption of hydroquinone in humans: effect of 1-dodecylazacycloheptan-2-one (azone) and the 2-ethylhexyl ester of 4-(dimethylamino)benzoic acid (Escalol 507). |
| PubMed: | Percutaneous absorption and elimination of the penetration enhancer Azone in humans. |
| PubMed: | Combination effect of penetration enhancers and propylene glycol on in vitro transdermal absorption of insulin. |
| PubMed: | Effect of penetration enhancers on the permeation of mannitol, hydrocortisone and progesterone through human skin. |
| PubMed: | Topical administration of tetrasodium-meso-tetraphenylporphinesulfonate (TPPS) and red light irradiation for the treatment of superficial neoplastic lesions. |
| PubMed: | Topical administration of tetrasodium-meso-tetraphenyl-porphinesulfonate (TPPS): correlation between drug penetration and depth of necrosis in skin of nude mice following red light irradiation. |
| PubMed: | Effect of Azone on the percutaneous absorption of 5-fluorouracil from gels in hairless rats. |
| PubMed: | Gel ointment of verapamil for percutaneous absorption. |
| PubMed: | Inhibitory effect of Azone (1-dodecylazacycloheptan-2-one) on herpes simplex viruses. In vivo and in vitro studies. |
| PubMed: | Dermal penetration enhancement profile of hexamethylenelauramide and its homologues: in vitro versus in vivo behavior of enhancers in the penetration of hydrocortisone. |
| PubMed: | Systemic effects of topically applied trichothecenes. III. The role of absorption enhancers. |
| PubMed: | Topical tritiated thymidine for epidermal growth fraction determination. |
| PubMed: | Pharmacodynamic measurement of percutaneous penetration enhancement in vivo. |
| PubMed: | Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as a poorly absorbable drug. III. Histological study after addition of various absorption promoters in rats. |
| PubMed: | Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as poorly absorbable drugs. II. Study on the absorption promoting effect of azone. |
| PubMed: | Influence of 1-dodecylazacycloheptan-2-one (Azone) on the topical therapy of cutaneous herpes simplex virus type 1 infection in hairless mice with 2',3'-di-O-acetyl-9-beta-D-arabinofuranosyladenine and 5'-O-valeryl-9-beta-D-arabinofuranosyladenine. |
| PubMed: | Facilitated transport of sodium salicylate across an artificial lipid membrane by Azone. |
| PubMed: | Effect of the absorption enhancer, Azone, on the transport of 5-fluorouracil across hairless rat skin. |
| PubMed: | Concentration-dependent enhancement of 1-dodecylazacycloheptan-2-one on the percutaneous penetration kinetics of triamcinolone acetonide. |
| PubMed: | Effect of azone and propylene glycol on penetration of trifluorothymidine through skin and efficacy of different topical formulations against cutaneous herpes simplex virus infections in guinea pigs. |
| PubMed: | Enhanced percutaneous penetration with 1-dodecylazacycloheptan-2-one. |
| PubMed: | [Investigations on the interference of some new azopyrazolones in the metabolism of ethanol]. |