Articles:
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poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy- (51 mol PO average molar ratio)
Notes:
None found
| CAS Number: | 25322-69-4 |  3D/inchi
|
| Other: | 100357-60-6 | |
| ECHA ELINCS - REACH Pre-Reg: | 500-039-8 | |
| Nikkaji Web: | J101.144H | |
| XlogP3: | -0.70 (est) | |
| Formula: | (C3 H8 O2)mult-H2 O | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
skin conditioning |
Suppliers:
| None found |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intravenous-dog LDLo 20 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. unreported-guinea pig LD50 1200 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981. intraperitoneal-mouse LD50 113 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. intraperitoneal-mouse LD50 195 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. intraperitoneal-mouse LD50 700 mg/kg BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. intraperitoneal-mouse LD50 3600 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. unreported-mouse LD50 4255 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981. intraperitoneal-rat LD50 230 uL/kg Union Carbide Data Sheet. Vol. 7/23/1970 intraperitoneal-rat LD50 460 uL/kg Union Carbide Data Sheet. Vol. 10/16/1973 intraperitoneal-rat LD50 4470 mg/kg BEHAVIORAL: TREMOR AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 448, 1951. intravenous-rat LD50 100 uL/kg Union Carbide Data Sheet. Vol. 7/23/1970 intravenous-rat LD50 200 uL/kg Union Carbide Data Sheet. Vol. 10/16/1973 intravenous-rat LD50 710 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 448, 1951. oral-rat LD50 35600 uL/kg Union Carbide Data Sheet. Vol. 3/27/1969 oral-rat LD50 56600 uL/kg Union Carbide Data Sheet. Vol. 3/28/1969 oral-rat LD50 > 2000 mg/kg Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl oral-rat LD50 2150 mg/kg Union Carbide Data Sheet. Vol. 7/23/1970 oral-rat LD50 2410 mg/kg Union Carbide Data Sheet. Vol. 10/16/1973 oral-rat LD50 3750 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981. oral-rat LD50 4190 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1413, 1986. oral-rat LD50 7250 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1413, 1986. oral-rat LD50 9760 mg/kg Union Carbide Data Sheet. Vol. 5/19/1960 oral-rat LD50 10334 mg/kg Dow Chemical Company Reports. Vol. MSD-395 oral-rat LD50 14800 mg/kg "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969. oral-rat LD50 > 15000 mg/kg Dow Chemical Company Reports. Vol. MSD-508 | |
| Dermal Toxicity: | |
|
skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 3/20/1973 skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 10/16/1973 skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 7/23/1970 skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 5/19/1960 skin-rabbit LD50 20 mL/kg Union Carbide Data Sheet. Vol. 3/27/1969 skin-rabbit LD50 20 mL/kg Union Carbide Data Sheet. Vol. 3/28/1969 skin-rabbit LD50 > 10000 mg/kg Dow Chemical Company Reports. Vol. MSD-95 skin-rabbit LD50 > 30000 mg/kg Dow Chemical Company Reports. Vol. MSD-395 | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic ingredient for skin conditioning | ||
| Recommendation for ppg-51 usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for ppg-51 flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 25322-69-4 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 32881 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| 2-(2-hydroxypropoxy)propan-1-ol (ppg-51) | |
| Chemidplus: | 0025322694 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | TR5775000 for cas# 25322-69-4 |
References:
| 2-(2-hydroxypropoxy)propan-1-ol (ppg-51) | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 25322-69-4 |
| Pubchem (cid): | 32881 |
| Pubchem (sid): | 134996365 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| 2-(2- | hydroxypropoxy)propan-1-ol (ppg-51) |
| poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy- (51 mol PO average molar ratio) | |
| polyoxypropylene (51) | |
| polypropylene glycol (51) |