copper picolinate
2-pyridinecarboxylic acid, copper(2+) salt (2:1)
 
Notes:
None found
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CAS Number: 27744-35-0Picture of molecule3D/inchi
FDA UNII: OAR053I14K
Molecular Weight: 307.75256000
Formula: C12 H8 Cu N2 O4
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Category: oral care agents
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: oral care agents
soothing agents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: oral care agents
Recommendation for copper picolinate usage levels up to:
 not for fragrance use.
 
Recommendation for copper picolinate flavor usage levels up to:
 not for flavor use.
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Safety References:
AIDS Citations: Search
Cancer Citations: Search
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 14963587
National Institute of Allergy and Infectious Diseases: Data
 copper;pyridine-2-carboxylate
Chemidplus: 0027744350
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References:
 copper;pyridine-2-carboxylate
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 14963587
Pubchem (sid): 162828521
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 copper;pyridine-2-carboxylate
 copper(2+) di(2-pyridinecarboxylate)
 copper(2+) dipyridine-2-carboxylate
 copper(II) picolinate
 copperpicolinate
2-pyridinecarboxylic acid, copper complex dihydrate
2-pyridinecarboxylic acid, copper(2+) salt (2:1)
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Articles:
PubMed: Monopicolinate Cross-Bridged Cyclam Combining Very Fast Complexation with Very High Stability and Inertness of Its Copper(II) Complex.
PubMed: Picolinic acid based Cu(II) complexes with heterocyclic bases - Crystal structure, DNA binding and cleavage studies.
PubMed: Enantiomeric in vitro DNA binding, pBR322 DNA cleavage and molecular docking studies of chiral L- and D-ternary copper(II) complexes of histidine and picolinic acid.
PubMed: Synthesis of cyclobakuchiols A, B, and C by using conformation-controlled stereoselective reactions.
PubMed: Monopicolinate-dipicolyl derivative of triazacyclononane for stable complexation of Cu2+ and 64Cu2+.
PubMed: Monopicolinate cyclen and cyclam derivatives for stable copper(II) complexation.
PubMed: Cu(I)-catalyzed annulation for the synthesis of substituted naphthalenes using o-bromobenzaldehydes and β-ketoesters as substrates.
PubMed: Evaluation of the binding of oxovanadium(IV) to human serum albumin.
PubMed: [Copper compounds ameliorate cardiovasclur dysfunction and diabetes in animals].
PubMed: Chemoselectivity in the Cu-catalyzed O-arylation of phenols and aliphatic alcohols.
PubMed: Diaqua-(6-bromo-picolinato-κN,O)(nitrato-κO,O)copper(II).
PubMed: Cu-catalyzed arylation of phenols: synthesis of sterically hindered and heteroaryl diaryl ethers.
PubMed: Orthogonal Cu- and Pd-based catalyst systems for the O- and N-arylation of aminophenols.
PubMed: Formation of chiral C(sp3)-C(sp) bond by allylic substitution of secondary allylic picolinates and alkynyl copper reagents.
PubMed: Stability, water exchange, and anion binding studies on lanthanide(III) complexes with a macrocyclic ligand based on 1,7-diaza-12-crown-4: extremely fast water exchange on the Gd3+ complex.
PubMed: (Acetato-kappaO)aqua(1H-imidazole-kappaN3)(picolinato-kappa2N,O)copper(II) 0.87-hydrate: a Z' > 1 structure.
PubMed: Metal complexes of a picolinate-based nitronyl nitroxide free radical.
PubMed: Separation of transition metals on a poly-iminodiacetic acid grafted polymeric resin column with post-column reaction detection utilising a paired emitter-detector diode system.
PubMed: A mononuclear and a mixed-valence chain polymer arising from copper(II) halide chemistry and the use of 2,2'-pyridil.
PubMed: [6-(3,5-Dimethyl-1H-pyrazol-1-yl)picolinato](pyridine-2,6-dicarboxyl-ato)copper(II) dihydrate.
PubMed: Bis[3-chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)picolinato-κO,N,N']copper(II) tetra-hydrate.
PubMed: Room-temperature copper-catalyzed alpha-arylation of malonates.
PubMed: Unusual oxidation of an N-heterocycle ligand in a metal-organic framework.
PubMed: Antidiabetic copper(II)-picolinate: impact of the first transition metal in the metallopicolinate complexes.
PubMed: An orthogonal ferromagnetically coupled tetracopper(II) 2 x 2 homoleptic grid supported by micro-O4 bridges and its DFT study.
PubMed: [Synthesis and spectral analysis of metal-N-glycoside complexes and studies of catalyzed ester hydrolytic kinetics].
PubMed: Hydrolysis of p-nitrophenyl picolinate catalyzed by metal complexes of N-alkyl-3,5-bis(hydroxymethyl)-1,2,4-triazole in CTAB micelles.
PubMed: trans-Diaquabis(6-hydroxypicolinato-kappa2N,O2)copper(II).
PubMed: Effects of supplemental copper and chromium on the serum and egg traits of laying hens.
PubMed: Direct determination of copper in urine using a sol-gel optical sensor coupled to a multicommutated flow system.
PubMed: Dipicolinic acid prevents the copper-dependent oxidation of low density lipoprotein.
PubMed: A cofactor approach to copper-dependent catalytic antibodies.
PubMed: Metallomicellar Catalysis Hydrolysis of p-Nitrophenyl Picolinate Catalyzed by Copper(II), Nickel(II), and Zinc(II) Complexes of Long Alkyl Pyridine Ligands in Micellar Solution.
PubMed: Beneficial effects of chromium on glucose and lipid variables in control and somatotropin-treated pigs are associated with increased tissue chromium and altered tissue copper, iron, and zinc.
PubMed: Chromium supplementation and resistance training: effects on body composition, strength, and trace element status of men.
PubMed: Complexometric titrations of protein-bound metal ions: a method for determining binding constants.
PubMed: Uptake of copper from brass vessels by bovine milk and its relevance to Indian childhood cirrhosis.
PubMed: Influence of dietary picolinic acid on mineral metabolism in the rat.
PubMed: Effects of the interrelationship between dietary protein and minerals on tissue content of trace metals in streptozotocin-diabetic rats.
PubMed: [Substituted picolinic acids as DBH inhibitors. Inhibition of dopamine beta-hydroxylase and antihypertensive action].
PubMed: Metal-binding ligands in Viokase.
PubMed: In vitro competition between calcium phytate and the soluble fraction of rat small intestine contents for cadmium, copper and zinc.
PubMed: Copper bioavailability and requirements.
PubMed: Detection of low molecular weight copper(II) and zinc(II) binding ligands in ultrafiltered milks-the citrate connection.
PubMed: Zinc absorption in the rat.
PubMed: Spectrophotometric determination of vanadium after extraction as vanadium(III) picolinate.
PubMed: HYDROLYSIS OF PROTOLYTIC ESTERS. 3. COPPER-CATALYZED HYDROLYSIS OF ETHYL PICOLINATE.
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