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sodium salt of the sulfuric acid ester of dextran
Notes:
a group of glucose polymers made by certain bacteria. dextrans are used therapeutically as plasma volume expanders and anticoagulants. they are also commonly used in biological experimentation and in industry for a wide variety of purposes. long-chain polymer of glucose containing 17-20% sulfur. it has been used as an anticoagulant and also has been shown to inhibit the binding of hiv-1 to cd4-positive t-lymphocytes. it is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GC2426 Dextran sulfate sodium salt, MW approx. 500,000
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| CAS Number: | 9011-18-1 | |
| Other(deleted CASRN): | 207464-10-6 | |
| MDL: | MFCD00081551 | |
Category: gelling agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
gel forming agents viscosity controlling agents |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Dextran sulfate sodium salt |
| Chemical-navi - Nikkol |
| DST-H
Odor: characteristic Use: Anti-swelling agent for face and body; promotes blood circulations by increasing NO production in epidermal cells; clinically-proven slimming effect. |
| Glentham Life Sciences |
| Dextran sulfate sodium salt, MW approx. 500,000 |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intravenous-mouse LD50 2350 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979. oral-mouse LD50 25200 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ATAXIA Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979. intravenous-rabbit LD50 19000 mg/kg Drugs in Japan Vol. 6, Pg. 481, 1982. intravenous-rat LD50 473 mg/kg BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979. oral-rat LD50 20600 mg/kg BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | gelling agents | ||
| Recommendation for sodium dextran sulfate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for sodium dextran sulfate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| Chemical Carcinogenesis Research Information System: | Search |
| Carcinogenic Potency Database: | Search |
| EPA Substance Registry Services (TSCA): | 9011-18-1 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| Chemidplus: | 0009011181 |
| RTECS: | HH9290000 for cas# 9011-18-1 |
References:
| Canada Domestic Sub. List: | 9011-18-1 |
| Pubchem (sid): | 135030727 |
Other Information:
| HMDB (The Human Metabolome Database): | Search |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| dexnon | |
| dextran sodium sulfate | |
| dextran sulfate sodium salt | |
| dextrarine | |
| DST-H | |
| sodium salt of the sulfuric acid ester of dextran |