Articles:
6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone - 2-aminoethanol (1:1)
Notes:
synthetic antifungal agent.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 41621-49-2 Ciclopirox ethanolamine >98% Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GA7329 Ciclopirox olamine
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Jiangyin Healthway International Trade Co., Ltd Independent Ingredients Supplier We provide custom synthesis and contract manufacturing from milligrams to metric tonnes. Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals. Email: Info Email: Sales Voice: 86-510-86023169 Fax: 86-510-86023170 Mobile 0086-13093133011 Services Biochemical Natural Food Colour New functional food ingredients Product(s): HLC-1101 Ciclopirox Olamine
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| CAS Number: | 41621-49-2 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 255-464-9 | |
| FDA UNII: | 50MD4SB4AP | |
| MDL: | MFCD00078997 | |
| Molecular Weight: | 268.35688000 | |
| Formula: | C14 H24 N2 O3 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: antidandruff, antimicrobial agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antidandruff agents antimicrobial agents |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Ciclopirox ethanolamine >98%
Odor: characteristic Use: Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator. |
| Glentham Life Sciences |
| Ciclopirox olamine |
| Jiangyin Healthway |
| Ciclopirox Olamine |
| New functional food ingredients |
| M.C.Biotec |
| Ciclopirox Olamine
Odor: characteristic Use: Ciclopirox has broad-spectrum action against dermatophytes, yeast, and fungi. Its anti-inflammatory activity has been demonstrated in human polymorphonuclear cells. This agent also inhibits prostaglandin and leukotriene synthesis. Ciclopirox olamine was effective and safe for mild-to-moderate dandruff. |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Ciclopirox Olamine ≥98% |
| Sigma-Aldrich |
| For experimental / research use only. |
| Ciclopirox Olamine |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LD50 83 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 57, 1975. intravenous-mouse LD50 71 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 57, 1975. oral-mouse LD50 1740 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 107, 1977. oral-rabbit LD50 > 3065 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1328, 1981. intraperitoneal-rat LD50 146 mg/kg BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 57, 1975. intravenous-rat LD50 72 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 107, 1977. oral-rat LD50 2350 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 107, 1977. | |
| Dermal Toxicity: | |
|
subcutaneous-mouse LD50 1730 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 107, 1977. subcutaneous-rat LD50 > 2500 mg/kg Drugs in Japan Vol. -, Pg. 510, 1995. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | antidandruff, antimicrobial agents | ||
| Recommendation for ciclopirox olamine usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for ciclopirox olamine flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 38911 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one | |
| Chemidplus: | 0041621492 |
| RTECS: | UU7785500 for cas# 41621-49-2 |
References:
| 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 38911 |
| Pubchem (sid): | 135001742 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| KEGG (GenomeNet): | D01364 |
| HMDB (The Human Metabolome Database): | Search |
| MedlinePlusSupp: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| 2- | aminoethanol compd. with 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone (1:1) |
| 2- | aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one |
| batrafen | |
| ciclobirox olamine | |
| ciclopirox | |
| ciclopirox ethanolamine | |
| ciclopirox ethanolamine salt (1:1) | |
| ciclopiroxethanolamine salt | |
| ciclopiroxolamin | |
| ciclopiroxolamine | |
| 6- | cyclohexyl-1-hydroxy-4-methyl-1H-pyridin-2-one, 2-amino-ethanol |
| 6- | cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone - 2-aminoethanol (1:1) |
| 6- | cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone compd. with 2-aminoethanol (1:1) |
| 6- | cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone compound with 2-aminoethanol (1:1) |
| 6- | cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt |
| 6- | cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone, 2-aminoethanol salt |
| 6- | cyclohexyl-1-hydroxy-4-methylhydropyridin-2-one, 2-aminoethan-1-ol |
| 6- | cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-on--2-aminoethanol(1:1) |
| 6- | cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1) |
| mycoster | |
| 2(1H)- | pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-, compd. with 2-aminoethanol (1:1) |
| terit |