flutriafol
1H-1,2,4-triazole-1-ethanol, a-(2-fluorophenyl)-a-(4-fluorophenyl)-
 
Notes:
fungicide.
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CAS Number: 76674-21-0Picture of molecule3D/inchi
Other(deleted CASRN): 1135441-08-5
FDA UNII: 83P8CT2Z3H
Nikkaji Web: J372.951F
Beilstein Number: 8155287
MDL: MFCD00144319
XlogP3: 2.30 (est)
Molecular Weight: 301.29661640
Formula: C16 H13 F2 N3 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 130.00 °C. @ 760.00 mm Hg
Boiling Point: 506.50 °C. @ 760.00 mm Hg (est)
Flash Point: 500.00 °F. TCC ( 260.10 °C. ) (est)
logP (o/w): 2.290
Soluble in:
 water, 130 mg/L @ 20 °C (exp)
 water, 432.4 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
Flutriafol
Sigma-Aldrich
For experimental / research use only.
Flutriafol PESTANAL®, analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-guinea pig LD50  200 mg/kg
Defense des Vegetaux. Vol. 38, Pg. 77, 1984.

oral-mouse LD50  179 mg/kg
Defense des Vegetaux. Vol. 38, Pg. 77, 1984.

oral-rabbit LD50  200 mg/kg
Defense des Vegetaux. Vol. 38, Pg. 77, 1984.

oral-rat LD50  1140 mg/kg
Pesticide Manual. Vol. 9, Pg. 427, 1991.

Dermal Toxicity:
skin-rabbit LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 427, 1991.

skin-rat LD50 > 1000 mg/kg
Pesticide Manual. Vol. 9, Pg. 427, 1991.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for flutriafol usage levels up to:
 not for fragrance use.
 
Recommendation for flutriafol flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the modification of the existing MRLs for flutriafol in pome fruits, peaches, cherries and plums
View page or View pdf
Reasoned opinion on the review of the existing maximum residue levels (MRLs) for flutriafol according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
Setting of import tolerance for flutriafol in strawberries
View page or View pdf
Setting of import tolerance for flutriafol in cucurbits with edible peel
View page or View pdf
Setting of import tolerance for flutriafol in hops
View page or View pdf
Evaluation of confirmatory data following the Article 12 MRL review and setting of an import tolerance for flutriafol in cucurbits (inedible peel)
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 91727
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)ethanol
Chemidplus: 0076674210
RTECS: XZ4825000 for cas# 76674-21-0
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References:
 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)ethanol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 91727
Pubchem (sid): 135048908
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C18734
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)ethanol
1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol
1,1-bis(4-fluorophenyl)-2-(1,2,4-triazolyl)ethan-1-ol
(±)-a-(2-fluorophenyl)-a-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol
a-(2-fluorophenyl)-a-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol
1-(2-fluorphenyl)-1-(4-fluorphenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol
 flutriafen
1H-1,2,4-triazole-1-ethanol, a-(2-fluorophenyl)-a-(4-fluorophenyl)-
1H-1,2,4-triazole-1-ethanol, a-(2-fluorophenyl)-a-(4-fluorophenyl)-, (±)-
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Articles:
PubMed: Simultaneous enantioselective determination of triazole fungicide flutriafol in vegetables, fruits, wheat, soil, and water by reversed-phase high-performance liquid chromatography.
PubMed: Green synthesis of a typical chiral stationary phase of cellulose-tris(3, 5-dimethylphenylcarbamate).
PubMed: Role of ionotropic glutamatergic receptors and nitric oxide in the effects of flutriafol, a triazole fungicide, on the in vivo striatal dopamine release.
PubMed: Dissipation and residues of flutriafol in wheat and soil under field conditions.
PubMed: Dissipation and residues of flutriafol in wheat and soil under field conditions.
PubMed: Determination of fungicide residues in baby food by liquid chromatography-ion trap tandem mass spectrometry.
PubMed: [Determination of 11 triazole fungicides in fruits using solid phase extraction and gas chromatography-tandem mass spectrometry].
PubMed: Gender-related differences in stereoselective degradation of flutriafol in rabbits.
PubMed: Enantiomeric separation of triazole fungicides with 3-μm and 5-μml particle chiral columns by reverse-phase high-performance liquid chromatography.
PubMed: Synthesis and application of a novel molecularly imprinted polymer-coated stir bar for microextraction of triazole fungicides in soil.
PubMed: Validation and application of an analytical method for determining pesticides in the gas phase of ambient air.
PubMed: In vitro effects of flutriafol and azoxystrobin on Beauvaria bassiana and its efficacy against Tetranychus urticae.
PubMed: Fungicide dissipation and impact on metolachlor aerobic soil degradation and soil microbial dynamics.
PubMed: Comparative effects of pesticides on in vivo dopamine release in freely moving rats.
PubMed: Evaluation of the effects and mechanisms of action of flutriafol, a triazole fungicide, on striatal dopamine release by using in vivo microdialysis in freely moving rats.
PubMed: Enantiomer separation of triazole fungicides by high-performance liquid chromatography.
PubMed: Rapid removal of flutriafol in water by zero-valent iron powder.
PubMed: Analyses of pesticide residues in fruit-based baby food by liquid chromatography/electrospray ionization time-of-flight mass spectrometry.
PubMed: Current-use and legacy pesticide history in the Austfonna Ice Cap, Svalbard, Norway.
PubMed: Capillary electrophoresis for analyzing pesticides in fruits and vegetables using solid-phase extraction and stir-bar sorptive extraction.
PubMed: Direct enantiomeric resolutions of chiral triazole pesticides by high-performance liquid chromatography.
PubMed: Empirical and modeling evidence of regional atmospheric transport of current-use pesticides.
PubMed: Evaluation of solid-phase extraction and stir-bar sorptive extraction for the determination of fungicide residues at low-microg kg(-1) levels in grapes by liquid chromatography-mass spectrometry.
PubMed: Solid-phase microextraction liquid chromatography/tandem mass spectrometry to determine postharvest fungicides in fruits.
PubMed: Sterol composition of mycelia of the plant pathogenic ascomycete Leptosphaeria maculans.
PubMed: Transcription of sterol Delta(5,6)-desaturase and sterol 14alpha-demethylase is induced in the plant pathogenic ascomycete, Leptosphaeria maculans, during treatment with a triazole fungicide.
PubMed: Monitoring of five postharvest fungicides in fruit and vegetables by matrix solid-phase dispersion and liquid chromatography/mass spectrometry.
PubMed: Determination of fungicide residues in fruits and vegetables by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
PubMed: Simultaneous determination of six triazolic pesticide residues in apple and pear pulps by liquid chromatography with ultraviolet diode array detection.
PubMed: High-performance chiral separation of fourteen triazole fungicides by sulfated beta-cyclodextrin-mediated capillary electrophoresis.
PubMed: Effect of a triazole fungicide on the cellulose decomposition by the soil microflora.
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