garcinia kola seed extract
extract of garcinia kola seed ("bitter cola")
 
Notes:
None found
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Category: food additive
 
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 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 25 Extract of Garcinia kola seed ("bitter cola") View - notice PDF
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: food additive
Recommendation for garcinia kola seed extract usage levels up to:
 not for fragrance use.
 
Recommendation for garcinia kola seed extract flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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References:
None found
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Other Information:
FDA Listing of Food Additive Status: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 garcinia kola seed
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Synonyms:
 extract of garcinia kola seed ("bitter cola")
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Articles:
PubMed: Kolaviron improved resistance to oxidative stress and inflammation in the blood (erythrocyte, serum, and plasma) of streptozotocin-induced diabetic rats.
PubMed: A quantitative documentation of the composition of two powdered herbal formulations (antimalarial and haematinic) using ethnomedicinal information from ogbomoso, Nigeria.
PubMed: Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK.
PubMed: Kolaviron prevents ethylene glycol monoethyl ether-induced testicular apoptosis via down-regulation of stress proteins, Fas/Fas-L and caspases expressions in rats.
PubMed: Kolaviron protects against ethylene glycol monoethyl ether-induced toxicity in boar spermatozoa.
PubMed: Influence of kolaviron and vitamin E on ethylene glycol monoethyl ether-induced haematotoxicity and renal apoptosis in rats.
PubMed: Kolaviron prevents carbendazim-induced steroidogenic dysfunction and apoptosis in testes of rats.
PubMed: Hepatic, testicular and spermatozoa antioxidant status in rats chronically treated with Garcinia kolaseed.
PubMed: Protective effects of kolaviron and quercetin on cadmium-induced testicular damage and endocrine pathology in rats.
PubMed: Garcinia kola seeds: is the aqueous extract a true aphrodisiac in male Wistar rats?
PubMed: Chemoprotection of ethylene glycol monoethyl ether-induced reproductive toxicity in male rats by kolaviron, isolated biflavonoid from Garcinia kola seed.
PubMed: Antioxidative and chemopreventive properties of Vernonia amygdalina and Garcinia biflavonoid.
PubMed: Comparative study on the efficacy of Garcinia kola in reducing some heavy metal accumulation in liver of Wistar rats.
PubMed: Detection of a gentamicin-resistant burn wound strain of pseudomonas aeruginosa but sensitive to honey and garcinia kola (heckel) seed extract.
PubMed: Effect of dietary Garcinia kola seed on selected serum electrolytes and trace metals in male Albino rats.
PubMed: Effect of gavage treatment with pulverised Garcinia kola seeds on erythrocyte membrane integrity and selected haematological indices in male albino Wistar rats.
PubMed: Antimicrobial effects of three tropical plant extracts on Staphylococcus aureus, Escherichia coli and Candida albicans.
PubMed: Biocidal activity of partially purified fractions from methanolic extract of Garcinia kola (Heckel) seeds on bacterial isolates.
PubMed: Preparative isolation and identification of tyrosinase inhibitors from the seeds of Garcinia kola by high-speed counter-current chromatography.
PubMed: Effects of garcinia kola seed extract on ovulation, oestrous cycle and foetal development in cyclic female sprague-dawley rats.
PubMed: Effect of Ingestion of Ethanol Extract of Garcinia Kola Seed on Erythrocytes in Wistar rats.
PubMed: Protection against 2- acetyl aminofluorene-induced toxicity in mice by garlic (Allium sativum), bitter kola (Garcina kola seed) and honey.
PubMed: Attenuation of indomethacin- and HCl/ethanol-induced oxidative gastric mucosa damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seed.
PubMed: Hypoglycaemic and hypolipidaemic effects of fractions from kolaviron, a biflavonoid complex from Garcinia Kola in streptozotocin-induced diabetes mellitus rats.
PubMed: Possible anti-atherogenic effect of kolaviron (a Garcinia kola seed extract) in hypercholesterolaemic rats.
PubMed: Commonly consumed and naturally occurring dietary substances affect biomarkers of oxidative stress and DNA damage in healthy rats.
PubMed: Some physical properties of tabletted seed of Garcinia kola (HECKEL).
PubMed: In vivo evaluation of interaction between aqueous seed extract of Garcinia kola Heckel and ciprofloxacin hydrochloride.
PubMed: Possible protective effect of kolaviron on CCl4-induced erythrocyte damage in rats.
PubMed: Chemoprevention of 2-acetylaminofluorene-induced hepatotoxicity and lipid peroxidation in rats by kolaviron--a Garcinia kola seed extract.
PubMed: Potential use ofGarcinia kola as hop substitute in lager beer brewing.
PubMed: Protective effects of Garcinia kola seed extract against paracetamol-induced hepatotoxicity in rats.
PubMed: Evaluation of the antihepatotoxic activity of the biflavonoids of Garcinia kola seed.
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