glycerophospholipid cholesterol acyltransferase
 
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Category: enzyme preparations and microorganisms
 
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GRN 265 Glycerophospholipid cholesterol acyltransferase (GCAT) enzyme preparation from Bacillus licheniformis expressing a modified GCAT gene from Aeromonas salmonicida subsp. salmonicida View - notice PDF
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
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Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: enzyme preparations and microorganisms
Recommendation for glycerophospholipid cholesterol acyltransferase usage levels up to:
 not for fragrance use.
 
Recommendation for glycerophospholipid cholesterol acyltransferase flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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References:
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Other Information:
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
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Potential Blenders and core components note
 
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Occurrence (nature, food, other): note
 glycerophospholipid cholesterol acyltransferase
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Synonyms:
glycerophospholipid cholesterol acyltransferase
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Articles:
PubMed: Diverse Profiles of N-acyl Homoserine L-Lactones, Biofilm, Virulence Genes and Integrons in Food-Borne Aeromonas Isolates.
PubMed: Evaluation of sterol transport from the endoplasmic reticulum to mitochondria using mitochondrially targeted bacterial sterol acyltransferase in Saccharomyces cerevisiae.
PubMed: Salmonella modulation of the phagosome membrane, role of SseJ.
PubMed: Molecular characterization of Aeromonas species isolated from farmed eels (Anguilla japonica).
PubMed: Legionella phospholipases implicated in infection: determination of enzymatic activities.
PubMed: Characterization and virulence potential of phenotypically diverse Aeromonas veronii isolates recovered from moribund freshwater ornamental fishes of Kerala, India.
PubMed: A Salmonella typhimurium-translocated glycerophospholipid:cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions.
PubMed: Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid:cholesterol acyltransferase.
PubMed: Virulence potential and antibiotic susceptibility pattern of motile aeromonads associated with freshwater ornamental fish culture systems: a possible threat to public health.
PubMed: Isolation and characterization of virulent Aeromonas veronii from ascitic fluid of oscar Astronotus ocellatus showing signs of infectious dropsy.
PubMed: Detection and characterization of virulence genes and integrons in Aeromonas veronii isolated from catfish.
PubMed: The Salmonella SPI-2 effector SseJ exhibits eukaryotic activator-dependent phospholipase A and glycerophospholipid : cholesterol acyltransferase activity.
PubMed: Cloning and characterization of Photobacterium damselae ssp. piscicida phospholipase: an enzyme that shows haemolytic activity.
PubMed: Characterization of extracellular proteins produced by Aeromonas hydrophila AH-1.
PubMed: The global regulatory proteins LetA and RpoS control phospholipase A, lysophospholipase A, acyltransferase, and other hydrolytic activities of Legionella pneumophila JR32.
PubMed: SseJ deacylase activity by Salmonella enterica serovar Typhimurium promotes virulence in mice.
PubMed: Cellular sterol ester synthesis in plants is performed by an enzyme (phospholipid:sterol acyltransferase) different from the yeast and mammalian acyl-CoA:sterol acyltransferases.
PubMed: Characterization of the major secreted zinc metalloprotease- dependent glycerophospholipid:cholesterol acyltransferase, PlaC, of Legionella pneumophila.
PubMed: Distribution of virulence genes in clinical and environmental isolates of Aeromonas spp.
PubMed: Characterisation of Aeromonas spp. isolated from frozen fish intended for human consumption in Mexico.
PubMed: A DNA probe specific for Aeromonas colonies.
PubMed: Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine.
PubMed: Inhibition of hemolytic activity of Aeromonas salmonicida GCAT in rainbow trout red blood cells by a monoclonal antibody.
PubMed: Suppression of the humoral immune response of Atlantic salmon, Salmo salar L. by the 64 kDa serine protease of Aeromonas salmonicida.
PubMed: Generation and preliminary characterization of monoclonal antibodies directed to glycerophospholipid:cholesterol acyltransferase (GCAT) native epitopes of Aeromonas salmonicida.
PubMed: Defined deletion mutants demonstrate that the major secreted toxins are not essential for the virulence of Aeromonas salmonicida.
PubMed: Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII.
PubMed: The disulfide bond in the Aeromonas hydrophila lipase/acyltransferase stabilizes the structure but is not required for secretion or activity.
PubMed: [Recent knowledge on fish pathogenic bacteria Aeromonas salmonicida, Listonella anguillara and Cytophaga columnaris, and their virulence factors].
PubMed: A histological study of the pathological effect of lipopolysaccharide-free glycerophospholipid: cholesterol acyl transferase (GCAT) on Atlantic salmon (Salmo salar L.).
PubMed: Characterization of interfacial catalysis by Aeromonas hydrophila lipase/acyltransferase in the highly processive scooting mode.
PubMed: Physical and chemical characterization of the oligomerization state of the Aeromonas hydrophila lipase/acyltransferase.
PubMed: Stereochemical and positional specificity of the lipase/acyltransferase produced by Aeromonas hydrophila.
PubMed: Action of a microbial lipase/acyltransferase on phospholipid monolayers.
PubMed: Studies on the reaction mechanism of a microbial lipase/acyltransferase using chemical modification and site-directed mutagenesis.
PubMed: Glycerophospholipid:cholesterol acyltransferase complexed with lipopolysaccharide (LPS) is a major lethal exotoxin and cytolysin of Aeromonas salmonicida: LPS stabilizes and enhances toxicity of the enzyme.
PubMed: Extracellular secretion of cloned aerolysin and phospholipase by Aeromonas salmonicida.
PubMed: Molecular cloning of a phospholipid-cholesterol acyltransferase from Aeromonas hydrophila. Sequence homologies with lecithin-cholesterol acyltransferase and other lipases.
PubMed: The purification and some properties of H-lysin from Aeromonas salmonicida.
PubMed: Action of a microbial glycerophospholipid:cholesterol acyltransferase on plasma from normal and LCAT-deficient subjects.
PubMed: Intracellular accumulation of extracellular proteins by pleiotropic export mutants of Aeromonas hydrophila.
PubMed: Substrate specificity of bacterial glycerophospholipid:cholesterol acyltransferase.
PubMed: Purification and partial characterization of a bacterial phospholipid: cholesterol acyltransferase.
PubMed: Identification and characterization of outer membrane fragments released by Aeromonas sp.
PubMed: Distribution of glycerophospholipid-cholesterol acyltransferase in selected bacterial species.
PubMed: Presence of glycerophospholipid: cholesterol acyltransferase and phospholipase in culture supernatant of Aeromonas hydrophila.
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