inonotus obliquus
chaga mushroom
 
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None found
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Bristol Botanicals
Chaga powder Inonotus obliquus
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
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Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for inonotus obliquus usage levels up to:
 not for fragrance use.
 
Recommendation for inonotus obliquus flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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References:
None found
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 inonotus obliquus
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Synonyms:
chaga mushroom
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Articles:
PubMed: Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9.
PubMed: CARI III inhibits tumor growth in a melanoma-bearing mouse model through induction of G0/G1 cell cycle arrest.
PubMed: Inhibitory and Acceleratory Effects of Inonotus obliquus on Tyrosinase Activity and Melanin Formation in B16 Melanoma Cells.
PubMed: [Prevention of Inonotus obliquus polysaccharides for high power microwave radiation induced testicular injury in rats: an experimental research].
PubMed: Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats.
PubMed: [A study of the antiherpetic activity of the chaga mushroom (Inonotus obliquus) extracts in the Vero cells infected with the herpes simplex virus].
PubMed: Stimulated production of steroids in Inonotus obliquus by host factors from birch.
PubMed: Inhibitory effects of a polysaccharide extract from the Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), on the proliferation of human neurogliocytoma cells.
PubMed: Production of bioactive polysaccharides by Inonotus obliquus under submerged fermentation supplemented with lignocellulosic biomass and their antioxidant activity.
PubMed: Polysaccharides from Inonotus obliquus sclerotia and cultured mycelia stimulate cytokine production of human peripheral blood mononuclear cells in vitro and their chemical characterization.
PubMed: Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells.
PubMed: Medicinal plants of the Russian Pharmacopoeia; their history and applications.
PubMed: Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by suppressing MMP-2 and MMP-9 via downregulation of NF-κB signaling pathway.
PubMed: Insulin-sensitizing and beneficial lipid-metabolic effects of the water-soluble melanin complex extracted from Inonotus obliquus.
PubMed: Mycosynthesis: antibacterial, antioxidant and antiproliferative activities of silver nanoparticles synthesized from Inonotus obliquus (Chaga mushroom) extract.
PubMed: Chemical constituents from Inonotus obliquus and their biological activities.
PubMed: Chemical analysis and antioxidant activity of polysaccharides extracted from Inonotus obliquus sclerotia.
PubMed: 3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway.
PubMed: Anti-oxidant and anti-inflammatory activities of Inonotus obliquus and germinated brown rice extracts.
PubMed: Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation.
PubMed: Progress on understanding the anticancer mechanisms of medicinal mushroom: inonotus obliquus.
PubMed: Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus.
PubMed: Inhibitory effect of chaga mushroom extract on compound 48/80-induced anaphylactic shock and IgE production in mice.
PubMed: Aqueous extract from a Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), prevents herpes simplex virus entry through inhibition of viral-induced membrane fusion.
PubMed: Chemical properties and antioxidant activity of exopolysaccharides fractions from mycelial culture of Inonotus obliquus in a ground corn stover medium.
PubMed: Stimulatory effect of different lignocellulosic materials for phenolic compound production and antioxidant activity from Inonotus obliquus in submerged fermentation.
PubMed: Bioassay-guided isolation of DPP-4 inhibitory fractions from extracts of submerged cultured of Inonotus obliquus.
PubMed: [Protective activity of aqueous extracts from higher mushrooms against Herpes simplex virus type-2 on albino mice model].
PubMed: Physical modifications of polysaccharide from Inonotus obliquus and the antioxidant properties.
PubMed: Lanostanoids from fungi: a group of potential anticancer compounds.
PubMed: Antioxidative Properties of Crude Polysaccharides from Inonotus obliquus.
PubMed: Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus.
PubMed: Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice.
PubMed: [Triterpenoids from Inonotus obliquus protect mice against oxidative damage induced by CCl4].
PubMed: Chemical modification and antioxidant activities of polysaccharide from mushroom Inonotus obliquus.
PubMed: Antioxidant activities of five polysaccharides from Inonotus obliquus.
PubMed: Inonotus obliquus containing diet enhances the innate immune mechanism and disease resistance in olive flounder Paralichythys olivaceus against Uronema marinum.
PubMed: Antiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell cultures.
PubMed: Preparation of Chaga medicinal mushroom, Inonotus obliquus-fermented rice using solid-state fermentation and its taste quality and antioxidant property.
PubMed: Comparative study of contents of several bioactive components in fruiting bodies and mycelia of culinary-medicinal mushrooms.
PubMed: Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae): in vitro studies.
PubMed: In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae).
PubMed: Inonotus obliquus extracts suppress antigen-specific IgE production through the modulation of Th1/Th2 cytokines in ovalbumin-sensitized mice.
PubMed: [Protective effects and mechanism of Inonotus obliquus on asthmatic mice].
PubMed: Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus - a medicinal mushroom.
PubMed: Changes of ginsenoside content by mushroom mycelial fermentation in red ginseng extract.
PubMed: Involvements of S-nitrosylation and denitrosylation in the production of polyphenols by Inonotus obliquus.
PubMed: Comparison of hypoglycemic activity of fermented mushroom of Inonotus obliquus rich in vanadium and wild-growing I. obliquus.
PubMed: Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection.
PubMed: Effects of inotodiol extracts from inonotus obliquus on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line A549.
PubMed: Inonotus obliquus protects against oxidative stress-induced apoptosis and premature senescence.
PubMed: Analysis of antioxidant metabolites by solvent extraction from sclerotia of Inonotus obliquus (Chaga).
PubMed: Immunostimulating activity by polysaccharides isolated from fruiting body of Inonotus obliquus.
PubMed: Extract of Chaga mushroom (Inonotus obliquus) stimulates 3T3-L1 adipocyte differentiation.
PubMed: Production of antioxidant and antitumor metabolites by submerged cultures of Inonotus obliquus cocultured with Phellinus punctatus.
PubMed: An unusual lanostane-type triterpenoid, spiroinonotsuoxodiol, and other triterpenoids from Inonotus obliquus.
PubMed: Separation of an aqueous extract Inonotus obliquus (Chaga). A novel look at the efficiency of its influence on proliferation of A549 human lung carcinoma cells.
PubMed: Enhancement of exo-polysaccharide production and antioxidant activity in submerged cultures of Inonotus obliquus by lignocellulose decomposition.
PubMed: Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells.
PubMed: Effects of ultrasonic treatment on the physicochemical properties and DPPH radical scavenging activity of polysaccharides from mushroom Inonotus obliquus.
PubMed: Chemical diversity of biologically active metabolites in the sclerotia of Inonotus obliquus and submerged culture strategies for up-regulating their production.
PubMed: Optimization of hydroxyl radical scavenging activity of exo-polysaccharides from Inonotus obliquus in submerged fermentation using response surface methodology.
PubMed: Beneficial effects of the ethanol extract from the dry matter of a culture broth of Inonotus obliquus in submerged culture on the antioxidant defence system and regeneration of pancreatic beta-cells in experimental diabetes in mice.
PubMed: Phytochemical characteristics and hypoglycaemic activity of fraction from mushroom Inonotus obliquus.
PubMed: Quantitative determination of steroids in the fruiting bodies and submerged-cultured mycelia of Inonotus obliquus.
PubMed: Anti-inflammatory effects of Inonotus obliquus in colitis induced by dextran sodium sulfate.
PubMed: Optimization of ultrasonic/microwave assisted extraction (UMAE) of polysaccharides from Inonotus obliquus and evaluation of its anti-tumor activities.
PubMed: Gamma-irradiation improves the color and antioxidant properties of Chaga mushroom (Inonotus obliquus) extract.
PubMed: Prevention of hydrogen peroxide-induced oxidative stress in PC12 cells by 3,4-dihydroxybenzalacetone isolated from Chaga (Inonotus obliquus (persoon) Pilat).
PubMed: Cancer cell cytotoxicity of extracts and small phenolic compounds from Chaga [Inonotus obliquus (persoon) Pilat].
PubMed: Antioxidant activities of extracts and subfractions from Inonotus Obliquus.
PubMed: Anti-inflammatory effect of Inonotus obliquus, Polygala senega L., and Viburnum trilobum in a cell screening assay.
PubMed: Nitric oxide mediates the fungal-elicitor-enhanced biosynthesis of antioxidant polyphenols in submerged cultures of Inonotus obliquus.
PubMed: Cytostatic activity of peptide extracts of medicinal plants on transformed A549, H1299, and HeLa Cells.
PubMed: NMR-based metabonomic analysis on effect of light on production of antioxidant phenolic compounds in submerged cultures of Inonotus obliquus.
PubMed: Progress of research on Inonotus obliquus.
PubMed: Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT-29 human colon cancer cells.
PubMed: [Antitumor activity of the plant remedy peptide extract PE-PM in a new mouse T-lymphoma/eukemia model].
PubMed: Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide.
PubMed: Comparative study of antioxidant activity and antiproliferative effect of hot water and ethanol extracts from the mushroom Inonotus obliquus.
PubMed: Evaluation of antitumor activity of peptide extracts from medicinal plants on the model of transplanted breast cancer in CBRB-Rb(8.17)1Iem mice.
PubMed: Potential anticancer properties of the water extract of Inonotus [corrected] obliquus by induction of apoptosis in melanoma B16-F10 cells.
PubMed: Introduction to Distribution and Ecology of Sterile Conks of Inonotus obliquus.
PubMed: Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis.
PubMed: Antimutagenic effects of subfractions of Chaga mushroom (Inonotus obliquus) extract.
PubMed: Accumulation of antioxidant phenolic constituents in submerged cultures of Inonotus obliquus.
PubMed: Identification of Inonotus obliquus and analysis of antioxidation and antitumor activities of polysaccharides.
PubMed: Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice.
PubMed: Lanostane-type triterpenoids from the sclerotia of Inonotus obliquus possessing anti-tumor promoting activity.
PubMed: Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells.
PubMed: Identification of a novel blocker of IkappaBalpha kinase activation that enhances apoptosis and inhibits proliferation and invasion by suppressing nuclear factor-kappaB.
PubMed: New antioxidant polyphenols from the medicinal mushroom Inonotus obliquus.
PubMed: Sterol composition in field-grown and cultured mycelia of Inonotus obliquus.
PubMed: Anti-complementary Activities of Exo- and Endo-biopolymer Produced by Submerged Mycelial Culture of Eight Different Mushrooms.
PubMed: Antioxidant small phenolic ingredients in Inonotus obliquus (persoon) Pilat (Chaga).
PubMed: Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells.
PubMed: Analysis of aqueous extract of Inonotus obliquus.
PubMed: Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
PubMed: Reversal of the TPA-induced inhibition of gap junctional intercellular communication by Chaga mushroom (Inonotus obliquus) extracts: effects on MAP kinases.
PubMed: Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus.
PubMed: Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus.
PubMed: Immunomodulatory Activity of the Water Extract from Medicinal Mushroom Inonotus obliquus.
PubMed: Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus.
PubMed: In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus.
PubMed: Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.
PubMed: Antioxidant effect of Inonotus obliquus.
PubMed: Cellular and physiological effects of Ganoderma lucidum (Reishi).
PubMed: Biologically active compounds from Aphyllophorales (polypore) fungi.
PubMed: [Effect of cryosubstance Chagi on deposition or isolation of 90Sr and on the effect of prolonged external exposure to gamma-radiation].
PubMed: [The nature of melanin pigments from some micro- and macromycetes].
PubMed: [Physicochemical properties of melanins produced by Inonotus obliquus("chagi") in the nature and the cultivated fungus].
PubMed: [Melanin complex of the fungus Inonotus obliquus].
PubMed: [Effects of bioglycans from birch fungus Inonotus obliquus on the electrical activity of cells from the cardiac venous sinus of the frog].
PubMed: Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective.
PubMed: The effect of aqueous extracts from Inonotus obliquus on the mitotic index and enzyme activities.
PubMed: Effect of six species of white-rot basidiomycetes on the chemical composition and rumen degradability of wheat straw.
PubMed: The substances of plant origin that inhibit protein biosynthesis.
PubMed: Antimitotic activity of aqueous extracts of Inonotus obliquus.
PubMed: Fungi in Khanty folk medicine.
PubMed: Effect of the extracts from fungus Inonotus obliquus on catalase level in HeLa and nocardia cells.
PubMed: Antitumor Activity of Triterpenes in Inonotus obliquus.
PubMed: Experiments on Cultures of Inonotus obliquus.
PubMed: 3beta, 22-Dihydroxylanosta-7,9(11), 24-triene: A New, Minor Compound from Inonotus obliquus.
PubMed: 3beta-Hydroxy-lanosta-8,24-dien-21-al, a New Triterpene from Inontus obliquus.
PubMed: [Aqueous extracts of Inonotus obliquus vel. Poria obliqua in the diagnosis of leukemias].
PubMed: [Conditions for the formation of a pigment complex in Inonotus obliquus in artificial culture].
PubMed: [Nature and origin of water-soluble pigment complex formed by Inonotus obliquus].
PubMed: [Pharmacological and biological characteristics of Inonotus obliquus].
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