Articles: PubMed: Physiological aspects of seed recalcitrance: a case study on the tree Aesculus hippocastanum. PubMed: Ethnomedicinal plants of Shankaracharya Hill, Srinagar, J&K, India. PubMed: Escin reduces cell proliferation and induces apoptosis on glioma and lung adenocarcinoma cell lines. PubMed: Influence of extrahent on antioxidant capacity of Aesculus hippocastanum seeds. PubMed: Comparative study of antioxidant status in androgenic embryos of Aesculus hippocastanum and Aesculus flava. PubMed: Effects of aescin on cytochrome P450 enzymes in rats. PubMed: Plant extracts inhibit ADP-induced platelet activation in humans: their potential therapeutic role as ADP antagonists. PubMed: Synergistic protective effects of escin and low‑dose glucocorticoids on blood‑retinal barrier breakdown in a rat model of retinal ischemia. PubMed: The apoptotic effects of escin in the H-Ras transformed 5RP7 cell line. PubMed: Vacuolar status and water relations in embryonic axes of recalcitrant Aesculus hippocastanum seeds during stratification and early germination. PubMed: β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells. PubMed: Escin exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vivo and in vitro. PubMed: Effects of escin mixture from the seeds of Aesculus hippocastanum on obesity in mice fed a high fat diet. PubMed: Beneficial effects of Aesculus hippocastanum L. seed extract on the body's own antioxidant defense system on subacute administration. PubMed: Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis. PubMed: Modulation of activity of the adipocyte aquaglyceroporin channel by plant extracts. PubMed: Flavonoids in horse chestnut (Aesculus hippocastanum) seeds and powdered waste water byproducts. PubMed: [Physiological and biochemical characteristics of recalcitrant seed under the condition of true dormancy: a review]. PubMed: Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells. PubMed: Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies. PubMed: Using horsechestnut seed extract in the treatment of venous leg ulcers: a cost-benefit analysis. PubMed: Herbal medications for common ailments in the elderly. PubMed: Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review. PubMed: Toxicity of seeds of three Aesculus spp to chicks and hamsters. PubMed: [Anti-inflammatory effects of the extract of Aesculus hippocastanum L. (horse chesnut) seed].