| PubMed: | Valeriana officinalis root extract suppresses physical stress by electric shock and psychological stress by nociceptive stimulation-evoked responses by decreasing the ratio of monoamine neurotransmitters to their metabolites. |
| PubMed: | Molecular cloning and characterization of drimenol synthase from valerian plant (Valeriana officinalis). |
| PubMed: | The influence of standardized Valeriana officinalis extract on the CYP3A1 gene expression by nuclear receptors in in vivo model. |
| PubMed: | Can Valeriana officinalis root extract prevent early postoperative cognitive dysfunction after CABG surgery? A randomized, double-blind, placebo-controlled trial. |
| PubMed: | Valerian: no evidence for clinically relevant interactions. |
| PubMed: | Valeriana officinalis L. for conscious sedation of patients submitted to impacted lower third molar surgery: A randomized, double-blind, placebo-controlled split-mouth study. |
| PubMed: | The effects of Valeriana officinalis L. hydro-alcoholic extract on depression like behavior in ovalbumin sensitized rats. |
| PubMed: | Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway. |
| PubMed: | Metabolic flux phenotype of tobacco hairy roots engineered for increased geraniol production. |
| PubMed: | Three new germacrane-type sesquiterpenes with NGF-potentiating activity from Valeriana officinalis var. latiofolia. |
| PubMed: | Phytotherapy against insomnia: extravagant claims or an alternative medicine? |
| PubMed: | Characterization of two geraniol synthases from Valeriana officinalis and Lippia dulcis: similar activity but difference in subcellular localization. |
| PubMed: | Valeriana officinalis extract and its main component, valerenic acid, ameliorate D-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation. |
| PubMed: | Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster. |
| PubMed: | Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in primary insomnia in comparison to zolpidem: a randomized controlled trial. |
| PubMed: | Teratogenic risk perception and confidence in use of medicines in pairs of pregnant women and general practitioners based on patient information leaflets. |
| PubMed: | Adverse effects of herbal medicines: an overview of systematic reviews. |
| PubMed: | Valeriana officinalis Dry Plant Extract for Direct Compression: Preparation and Characterization. |
| PubMed: | Antioxidant effect and study of bioactive components of Valeriana sisymbriifolia and Nardostachys jatamansii in comparison to Valeriana officinalis. |
| PubMed: | Functional identification of valerena-1,10-diene synthase, a terpene synthase catalyzing a unique chemical cascade in the biosynthesis of biologically active sesquiterpenes in Valeriana officinalis. |
| PubMed: | Anxiolytic properties of Valeriana officinalis in the zebrafish: a possible role for metabotropic glutamate receptors. |
| PubMed: | Acylated iridoids from the roots of Valeriana officinalis var. latifolia. |
| PubMed: | Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis). |
| PubMed: | Phenotyping studies to assess the effects of phytopharmaceuticals on in vivo activity of main human cytochrome p450 enzymes. |
| PubMed: | Effects of valerian consumption during pregnancy on cortical volume and the levels of zinc and copper in the brain tissue of mouse fetus. |
| PubMed: | Pharmacokinetics of valerenic acid in rats after intravenous and oral administrations. |
| PubMed: | Enhanced chromatographic fingerprinting of herb materials by multi-wavelength selection and chemometrics. |
| PubMed: | Sesquiterpenoids and lignans from the roots of Valeriana officinalis L. |
| PubMed: | Complementary and Alternative Drugs Use among Preoperative Patients: A Cross-Sectional Study in Italy. |
| PubMed: | Three phases hollow fiber LPME combined with HPLC-UV for extraction, preconcentration and determination of valerenic acid in Valeriana officinalis. |
| PubMed: | Volvalerelactones A and B, two new sesquiterpenoid lactones with an unprecedented skeleton from Valeriana officinalis var. latifolia. |
| PubMed: | Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [H]Glutamate Binding to Rat Synaptic Membranes. |
| PubMed: | Valeriana officinalis ameliorates vacuous chewing movements induced by reserpine in rats. |
| PubMed: | The use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study (NCCTG Trial, N01C5). |
| PubMed: | [Medicinal plants for the treatment of generalized anxiety disorder: a review of controlled clinical studies]. |
| PubMed: | Evaluation of commercial essential oil samples on the growth of postharvest pathogen Monilinia fructicola (G. Winter) Honey. |
| PubMed: | Extract of valerian root (Valeriana officinalis L.) vs. placebo in treatment of obsessive-compulsive disorder: a randomized double-blind study. |
| PubMed: | Telemetry as a tool to measure sedative effects of a valerian root extract and its single constituents in mice. |
| PubMed: | Aqueous and Ethanolic Valeriana officinalis Extracts Change the Binding of Ligands to Glutamate Receptors. |
| PubMed: | Composition of essential oils in subterranean organs of three species of Valeriana L. |
| PubMed: | Pharmacokinetics of valerenic acid after single and multiple doses of valerian in older women. |
| PubMed: | Chemical analysis and biological activity of the essential oils of two valerianaceous species from China: Nardostachys chinensis and Valeriana officinalis. |
| PubMed: | Germacrane-type sesquiterpenoids from the roots of Valeriana officinalis var. latifolia. |
| PubMed: | Treating primary insomnia - the efficacy of valerian and hops. |
| PubMed: | Patterns of self-medication with medicinal plants and related adverse events--a South American survey. |
| PubMed: | Phytotherapeutics: an evaluation of the potential of 1000 plants. |
| PubMed: | Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats. |
| PubMed: | [Knowledge of perioperative risk associated with use of medicinal plants]. |
| PubMed: | [Detection of viral infection pathogens in medicinal plants grown in Ukraine]. |
| PubMed: | Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: possible involvement of adenosine. |
| PubMed: | Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. |
| PubMed: | Root colonization by symbiotic arbuscular mycorrhizal fungi increases sesquiterpenic acid concentrations in Valeriana officinalis L. |
| PubMed: | [HPLC fingerprint of the antiarrhythmic fraction of Valeriana officinalis]. |
| PubMed: | Iridoids and sesquiterpenoids from the roots of Valeriana officinalis. |
| PubMed: | Interactions of Valeriana officinalis L. and Passiflora incarnata L. in a patient treated with lorazepam. |
| PubMed: | Direct metabolic fingerprinting of commercial herbal tinctures by nuclear magnetic resonance spectroscopy and mass spectrometry. |
| PubMed: | Pinoresinol-4,4'-di-O-beta-D-glucoside from Valeriana officinalis root stimulates calcium mobilization and chemotactic migration of mouse embryo fibroblasts. |
| PubMed: | In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents. |
| PubMed: | Relaxing effects of Valeriana officinalis extracts on isolated human non-pregnant uterine muscle. |
| PubMed: | Total synthesis of valerenic acid, a potent GABAA receptor modulator. |
| PubMed: | A feasibility study of valerian extract for sleep disturbance in person with arthritis. |
| PubMed: | Preclinical toxicological assessment of a phytotherapeutic product--CPV (based on dry extracts of Crataegus oxyacantha L., Passiflora incarnata L., and Valeriana officinalis L.). |
| PubMed: | Toxicological assessment of P-9801091 plant mixture extract after chronic administration in CBA/HZg mice--a biochemical and histological study. |
| PubMed: | Transport of a GABAA receptor modulator and its derivatives from Valeriana officinalis L. s. l. across an in vitro cell culture model of the blood-brain barrier. |
| PubMed: | Cytoprotective effect of Valeriana officinalis extract on an in vitro experimental model of Parkinson disease. |
| PubMed: | A randomized clinical trial of valerian fails to improve self-reported, polysomnographic, and actigraphic sleep in older women with insomnia. |
| PubMed: | Analysis of the thrips fauna (Thysanoptera) on flowers of herbs. |
| PubMed: | Ethnophytotherapeutical research in the high Molise region (Central-Southern Italy). |
| PubMed: | [Studies on chemical constituents of Valeriana officinalis]. |
| PubMed: | Essential oil composition of Valeriana officinalis L. roots cultivated in Iran. Comparative analysis between supercritical CO2 extraction and hydrodistillation. |
| PubMed: | Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties. |
| PubMed: | Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. |
| PubMed: | Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system. |
| PubMed: | Valeriana officinalis does not alter the orofacial dyskinesia induced by haloperidol in rats: role of dopamine transporter. |
| PubMed: | Modulation of postsynaptic potentials in rat cortical neurons by valerian extracts macerated with different alcohols: involvement of adenosine A(1)- and GABA(A)-receptors. |
| PubMed: | Biological and analytical characterization of two extracts from Valeriana officinalis. |
| PubMed: | Identification of individual herbal drugs in tea mixtures using restriction analysis of ITS DNA and real-time PCR. |
| PubMed: | Valerian for sleep: a systematic review and meta-analysis. |
| PubMed: | Interaction of valerian extracts of different polarity with adenosine receptors: identification of isovaltrate as an inverse agonist at A1 receptors. |
| PubMed: | NF-kappaB modulators from Valeriana officinalis. |
| PubMed: | Commercial valerian interactions with [3H]Flunitrazepam and [3H]MK-801 binding to rat synaptic membranes. |
| PubMed: | Effects of aqueous, methanolic and chloroform extracts of rhizome and aerial parts of Valeriana officinalis L. on naloxone-induced jumping in morphine-dependent mice. |
| PubMed: | Authentication of Valeriana procera Kunth and comparative account of five Valeriana species. |
| PubMed: | Health effects of exposure to herb dust in valerian growing farmers. |
| PubMed: | Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. |
| PubMed: | New acylated clionasterol glycosides from Valeriana officinalis. |
| PubMed: | Preserved pharmacological activity of hepatocytes-treated extracts of valerian and St. John's wort. |
| PubMed: | Exposure to airborne microorganisms, dust and endotoxin during processing of valerian roots on farms. |
| PubMed: | A phase I clinical study of Andrographis paniculata fixed combination Kan Jang versus ginseng and valerian on the semen quality of healthy male subjects. |
| PubMed: | Genotoxicity and anti-genotoxicity of some traditional medicinal herbs. |
| PubMed: | Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro. |
| PubMed: | In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes. |
| PubMed: | Determination of metal content in valerian root phytopharmaceutical derivatives by atomic spectrometry. |
| PubMed: | Monograph. Valeriana officinalis. |
| PubMed: | Extraction of valerenic acids from valerian (Valeriana officinalis L.) rhizomes. |
| PubMed: | In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4. |
| PubMed: | The use of valerian in neuropsychiatry. |
| PubMed: | Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers. |
| PubMed: | Neuroprotective properties of Valeriana officinalis extracts. |
| PubMed: | Effect of supplemental tryptophan, vitamin E, and a herbal product on responses by pigs to vibration. |
| PubMed: | Stability control of valerian ground material and extracts: a new HPLC-method for the routine quantification of valerenic acids and lignans. |
| PubMed: | Essential oil of Valeriana officinalis L. cultivars and their antimicrobial activity as influenced by harvesting time under commercial organic cultivation. |
| PubMed: | Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteers. |
| PubMed: | [Consumption of medicinal herbs in patients attending a gastroenterology outpatient clinic]. |
| PubMed: | [Effects of Valeriana officinalis var. latifolia on expression of transforming growth factor beta 1 in hypercholesterolemic rats]. |
| PubMed: | Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis. |
| PubMed: | Analysis of responses to valerian root extract in the feline pulmonary vascular bed. |
| PubMed: | Mitogenic and comitogenic activities of polysaccharides from some European herbaceous plants. |
| PubMed: | A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health. |
| PubMed: | Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors. |
| PubMed: | (-)-3 beta,4 beta-epoxyvalerenic acid from Valeriana officinalis. |
| PubMed: | The importance of pharmacological synergy in psychoactive herbal medicines. |
| PubMed: | Analysis of sesquiterpenes in Valeriana officinalis by capillary electrophoresis. |
| PubMed: | Polysomnographic evaluation of the hypnotic effect of Valeriana edulis standardized extract in patients suffering from insomnia. |
| PubMed: | Synergy and other interactions in phytomedicines. |
| PubMed: | Ultrasound-assisted extraction of water-soluble polysaccharides from the roots of valerian (Valeriana officinalis L.). |
| PubMed: | Pacifigorgianes and tamariscene as constituents of Frullania tamarisci and Valeriana officinalis. |
| PubMed: | A1 adenosine receptors and their ligands: overview and recent developments. |
| PubMed: | Towards the industrial production of medicinal tincture by ultrasound assisted extraction. |
| PubMed: | Valeriana officinalis. |
| PubMed: | Influence of fibre coating in headspace solid-phase microextraction-gas chromatographic analysis of aromatic and medicinal plants. |
| PubMed: | [Interactions between herbal medicines and drugs]. |
| PubMed: | Valerian for insomnia: a systematic review of randomized clinical trials. |
| PubMed: | Valerian: Valeriana officinalis. |
| PubMed: | Herbal medications for common ailments in the elderly. |
| PubMed: | Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release. |
| PubMed: | The relevance of herbal treatments for psychiatric practice. |
| PubMed: | Extracts and constituents of Hypericum perforatum inhibit the binding of various ligands to recombinant receptors expressed with the Semliki Forest virus system. |
| PubMed: | Hypericum perforatum inhibits the binding of mu- and kappa-opioid receptor expressed with the Semliki Forest virus system. |
| PubMed: | Seasonal variation of the essential oil, valerenic acid and derivatives, and velopotriates in Valeriana officinalis roots and rhizomes, and the selection of plants suitable for phytomedicines. |
| PubMed: | [Isolation and receptor binding properties of alkaloids and lignans from Valeriana officialis L]. |
| PubMed: | Neurological stamp. Valeriana officinalis (garden heliotrope). |
| PubMed: | In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on GABAA receptor in rat brain. |
| PubMed: | [Clinical studies on the treatment of coronary heart disease with Valeriana officinalis var latifolia]. |
| PubMed: | Synaptosomal GABA release as influenced by valerian root extract--involvement of the GABA carrier. |
| PubMed: | Effects of a prolonged administration of valepotriates in rats on the mothers and their offspring. |
| PubMed: | High-yield production of valepotriates by hairy root cultures of Valeriana officnalis L. var. sambucifolia Mikan. |
| PubMed: | [Valeriana officinalis and Crataegus oxyacantha: toxicity from repeated administration and pharmacologic investigations]. |
| PubMed: | [Saliunca]. |
| PubMed: | Central nervous depressant activity of valerenic Acid in the mouse. |
| PubMed: | Valepotriate content in different in vitro cultures of Valerianaceae and characterization of Valeriana officinalis L. callus during a growth period. |
| PubMed: | Analysis of primary and secondary plant products in Valeriana officinalis callus during a growth cycle. |
| PubMed: | [Der Einfluss von Valerenal und Valerensäuren aus Valeriana officinalis auf die Aktivität von Ratten und den Dopamin-Metabolismus im Rattengehirn.] |
| PubMed: | Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. |
| PubMed: | [Effects of Valeriana officinalis L extract on cardiovascular system]. |
| PubMed: | Quantifying the effects of mild sedatives. |
| PubMed: | [Evaluation of the activity on the mouse CNS of several plant extracts and a combination of them]. |
| PubMed: | [Analytische und pharmakologische Aspekte des ätherischen Oles von Valeriana officinalis.] |
| PubMed: | Pharmacological screening of valerenal and some other components of essential oil of Valeriana officinalis. |
| PubMed: | [Composition of the flavonoids of Valeriana officinalis from the Asiatic part of the USSR]. |
| PubMed: | [Chemical weed control in the cropping of medicinal plants. Part 1: Valerian (Valeriana officinalis L.) (author's transl)]. |
| PubMed: | [Contribution to the study of valerian alcaloids (Valeriana officinalis, L.): actinidine and naphthyridylmethylketone, a new alkaloid (author's transl)]. |
| PubMed: | [Flavonoid makeup of Valeriana officinalis from the southern and central provinces of the Ukraine]. |
| PubMed: | [Active substances in Valeriana officinalis L]. |
| PubMed: | New methods in the cultivation of Valeriana officinalis. |
| PubMed: | [Biosynthesis of alkaloids, valtrates and volatile oils in the roots of Valeriana officinalis L. from radioactive precursors]. |
| PubMed: | [Permissible content of stalk residues in crude Valeriana officinalis]. |
| PubMed: | [Pharmacological studies on the constituents of crude drugs and plants. 1. Pharmacological actions of Valeriana officinalis Linńe var. latifolia Miquel]. |
| PubMed: | [Dependence of the valepotriate and essential oil content in Valeriana officinalis L.s.l. on various exogenous and endogenous factors]. |
| PubMed: | [Valeroside A--a glycoside from valerian (Valeriana officinalis L.)]. |
| PubMed: | Isolation, structure and synthesis of alkaloids from Valeriana officinalis L. |
| PubMed: | [Tests of "industrial lyophilization" of medicinal plants. 3. Valeriana officinalis L. Influence of lyophilization on the quality of the drug]. |
| PubMed: | [Comparative ethnomedical study of Valeriana officinalis L]. |
| PubMed: | [Separation of alkaloids from the dried roots and rhizomes of Valeriana officinalis L]. |
| PubMed: | Pharmacological investigation of certain Valeriana officinalis L. extracts. |
| PubMed: | Valeriana officinalis Linn., its polyploid forms and the structure of their rhizomes and roots. |
| PubMed: | [Yields in Valeriana officinalis cultivation]. |
| PubMed: | [Method for differentiation of preparations of Centranthus ruber DC from Valeriana officinalis L; preliminary note]. |
| PubMed: | [Cultivation of Valeriana officinalis]. |
| PubMed: | [Studies on the quality and capacity of Valeriana officinalis]. |
| PubMed: | [Studies on the modification of output and quality in Valeriana officinalis by growth technic and habitat]. |
| PubMed: | [Experiments on fertilization of Atropa belladonna and Valeriana officinalis]. |