nigella sativa seed tincture
black caraway seed tincture
 
Notes:
a plant genus of the family ranunculaceae that contains alpha-hederin, a triterpene saponin in the seeds, and is the source of black seed oil.
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Name: nigella sativa l. seed tincture
CAS Number: 90064-32-7 
ECHA EC Number: 290-094-1
Category: fragrance agents
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
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None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Recommendation for nigella sativa seed tincture flavor usage levels up to:
 not for flavor use.
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 nigella sativa l. seed tincture
Chemidplus: 0090064327
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References:
 nigella sativa l. seed tincture
Pubchem (sid): 135353902
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Potential Blenders and core components note
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 cumin black cumin seed
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Synonyms:
black caraway seed tincture
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Articles:
PubMed: Scolicidal Effects of Black Cumin Seed (Nigella sativa) Essential Oil on Hydatid Cysts.
PubMed: Enhanced cytotoxicity and apoptosis by thymoquinone in combination with zoledronic acid in hormone- and drug-resistant prostate cancer cell lines.
PubMed: Thymoquinone Inhibits Murine Leukemia WEHI-3 Cells In Vivo and In Vitro.
PubMed: The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes.
PubMed: Anti-microbial effect of Nigella sativa seed extract against staphylococcal skin Infection.
PubMed: Protective effect of thymoquinone against high-fructose diet-induced metabolic syndrome in rats.
PubMed: Apoptotic Activities of Thymoquinone, an Active Ingredient of Black Seed (Nigella sativa), in Cervical Cancer Cell Lines.
PubMed: Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway.
PubMed: Potential protective effects of Nigella sativa and Allium sativum against fructose-induced metabolic syndrome in rats.
PubMed: Mitigating role of thymoquinone rich fractions from Nigella sativa oil and its constituents, thymoquinone and limonene on lipidemic-oxidative injury in rats.
PubMed: Dietary supplementation of chloroquine with nigella sativa seed and oil extracts in the treatment of malaria induced in mice with plasmodium berghei.
PubMed: Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways.
PubMed: Endothelium-independent vasorelaxant effects of hydroalcoholic extract from Nigella sativa seed in rat aorta: the roles of Ca2+ and K+ channels.
PubMed: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase.
PubMed: Stable isotope dilution gas chromatography-mass spectrometry for quantification of thymoquinone in black cumin seed oil.
PubMed: Effects of Nigella sativa L. seed oil on abnormal semen quality in infertile men: a randomized, double-blind, placebo-controlled clinical trial.
PubMed: Natural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIα.
PubMed: Induction of apolipoprotein A-I gene expression by black seed (Nigella sativa) extracts.
PubMed: Increased 5-HT Levels Following Repeated Administration of Nigella sativa L. (Black Seed) Oil Produce Antidepressant Effects in Rats.
PubMed: Bioactivity-guided identification to delineate the immunomodulatory effects of methanolic extract of Nigella sativa seed on human peripheral blood mononuclear cells.
PubMed: Cytotoxicity of Nigella sativa seed oil and extract against human lung cancer cell line.
PubMed: Effect of dietary supplementation of black seed (N. Sativa L.) on lipid profile of patients suffering from diabetes.
PubMed: Metabolomics driven analysis of six Nigella species seeds via UPLC-qTOF-MS and GC-MS coupled to chemometrics.
PubMed: Topical Nigella Sativa for nasal symptoms in elderly.
PubMed: Authentication of Nigella sativa seed oil in binary and ternary mixtures with corn oil and soybean oil using FTIR spectroscopy coupled with partial least square.
PubMed: Thymoquinone causes multiple effects, including cell death, on dividing plant cells.
PubMed: The effect of thymoquinone, an active component of Nigella sativa, on isoproterenol induced myocardial injury.
PubMed: The effect of black seed (Nigella sativa) extract on FOXO3 expression in HepG2 cells.
PubMed: Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells.
PubMed: Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells.
PubMed: Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro.
PubMed: The investment in scent: time-resolved metabolic processes in developing volatile-producing Nigella sativa L. seeds.
PubMed: Thymoquinone: fifty years of success in the battle against cancer models.
PubMed: The clinical outcome of adjuvant therapy with black seed oil on intractable paediatric seizures: a pilot study.
PubMed: Lepidium sativum but not Nigella sativa affects carbamazepine disposition in an animal model.
PubMed: Comparative effects of using black seed (Nigella sativa), cumin seed (Cuminum cyminum), probiotic or prebiotic on growth performance, blood haematology and serum biochemistry of broiler chicks.
PubMed: Cellular responses with thymoquinone treatment in human breast cancer cell line MCF-7.
PubMed: Evaluation of topical black seed oil in the treatment of allergic rhinitis.
PubMed: Effect of Nigella sativa and Allium sativum coadminstered with simvastatin in dyslipidemia patients: a prospective, randomized, double-blind trial.
PubMed: Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration.
PubMed: Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway.
PubMed: Elucidation of mechanisms of actions of thymoquinone-enriched methanolic and volatile oil extracts from Nigella sativa against cardiovascular risk parameters in experimental hyperlipidemia.
PubMed: The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers.
PubMed: Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling.
PubMed: Nigella sativa seed extract: 1. Enhancement of sheep macrophage immune functions in vitro.
PubMed: Effects of selected bioactive natural products on the vascular endothelium.
PubMed: Effects of black cumin seed (Nigella sativa L.) on performance and immune system in newly evolved crossbred laying hens.
PubMed: Hepatoprotective and immunological functions of Nigella sativa seed oil against hypervitaminosis A in adult male rats.
PubMed: Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome.
PubMed: Effects of black seed oil on resolution of hepato-renal toxicity induced bybromobenzene in rats.
PubMed: Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity.
PubMed: Methanolic extract of Nigella sativa seed inhibits SiHa human cervical cancer cell proliferation through apoptosis.
PubMed: Blood pressure lowering effect of Nigella sativa L. seed oil in healthy volunteers: a randomized, double-blind, placebo-controlled clinical trial.
PubMed: Effects of Lepidium sativum, Nigella sativa and Trigonella foenum-graceum on phenytoin pharmacokinetics in beagle dogs.
PubMed: Anti-inflammatory effect of seeds and callus of Nigella sativa L. extracts on mix glial cells with regard to their thymoquinone content.
PubMed: Hormetic/cytotoxic effects of Nigella sativa seed alcoholic and aqueous extracts on MCF-7 breast cancer cells alone or in combination with doxorubicin.
PubMed: High-performance liquid chromatography quantification of principal antioxidants in black seed (Nigella sativa L.) phytopharmaceuticals.
PubMed: NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis.
PubMed: Distribution of primary and specialized metabolites in Nigella sativa seeds, a spice with vast traditional and historical uses.
PubMed: Cardiovascular benefits of black cumin (Nigella sativa).
PubMed: Use of complementary and alternative medicine by patients with cancer in Saudi Arabia.
PubMed: Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors.
PubMed: Can methanolic extract of Nigella sativa seed affect glyco-regulatory enzymes in experimental hepatocellular carcinoma?
PubMed: Biosynthesis of controllable size and shape gold nanoparticles by black seed (Nigella sativa) extract.
PubMed: The enhancing effects of alcoholic extract of Nigella sativa seed on fertility potential, plasma gonadotropins and testosterone in male rats.
PubMed: Cadmium-induced hepatotoxicity and its abrogation by thymoquinone.
PubMed: Thymoquinone prevents and ameliorates dextran sulfate sodium-induced colitis in mice.
PubMed: Characterization of secondary volatile profiles in Nigella sativa seeds from two different origins using accelerated solvent extraction and gas chromatography-mass spectrometry.
PubMed: Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo.
PubMed: Stabilization of emulsion and butter like products containing essential fatty acids using kalonji seeds extract and curcuminoids.
PubMed: Anticancer activity of Nigella sativa (black seed) - a review.
PubMed: Upregulation of chemoprotective enzymes and glutathione by Nigella sativa (black seed) and thymoquinone in CCl4-intoxicated rats.
PubMed: Protective effect of Nigella sativa oil against tramadol-induced tolerance and dependence in mice: role of nitric oxide and oxidative stress.
PubMed: Lindane-induced biochemical perturbations in rat serum and attenuation by omega-3 and Nigella sativa seed oil.
PubMed: Antiatherogenic Potential of Nigella sativa Seeds and Oil in Diet-Induced Hypercholesterolemia in Rabbits.
PubMed: Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E(2)P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump.
PubMed: Various extraction and analytical techniques for isolation and identification of secondary metabolites from Nigella sativa seeds.
PubMed: The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content.
PubMed: Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis.
PubMed: Nigella sativa seed extract and its bioactive compound thymoquinone: the new melanogens causing hyperpigmentation in the wall lizard melanophores.
PubMed: Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation.
PubMed: In vitro antituberculous activity of thymoquinone, an active principle of Nigella sativa.
PubMed: Determination of oxygen radical absorbance capacity of black cumin (Nigella sativa) seed quinone compounds.
PubMed: Investigation of lipids profiles of Nigella, lupin and artichoke seed oils to be used as healthy oils.
PubMed: Validated high-performance thin-layer chromatographic method for the quantification of thymoquinone in Nigella Sativa extracts and formulations.
PubMed: Phytochemical and biological investigation of the extracts of Nigella sativa L. seed waste.
PubMed: In vitro antifungal effect of black cumin seed quinones against dairy spoilage yeasts at different acidity levels.
PubMed: The protective effect of thymoquinone against sepsis syndrome morbidity and mortality in mice.
PubMed: Chemical composition of Nigella sativa L. seed extracts obtained by supercritical carbon dioxide.
PubMed: Amelioration of tamoxifen-induced liver injury in rats by grape seed extract, black seed extract and curcumin.
PubMed: Thymoquinone supplementation attenuates cyclophosphamide-induced cardiotoxicity in rats.
PubMed: Review on molecular and therapeutic potential of thymoquinone in cancer.
PubMed: Protective effects of black cumin (Nigella sativa) oil on TNBS-induced experimental colitis in rats.
PubMed: Analgesic effect of Nigella sativa seeds extract on experimentally induced pain in albino mice.
PubMed: Nigella sativa L. seed extract modulates the neurotransmitter amino acids release in cultured neurons in vitro.
PubMed: Comparative study of Nigella Sativa and triple therapy in eradication of Helicobacter Pylori in patients with non-ulcer dyspepsia.
PubMed: Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species.
PubMed: Evaluation of immunomodulatory effect of three herbal plants growing in Egypt.
PubMed: Structure-activity studies on therapeutic potential of Thymoquinone analogs in pancreatic cancer.
PubMed: Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide.
PubMed: Potential adjuvant effects of Nigella sativa seeds to improve specific immunotherapy in allergic rhinitis patients.
PubMed: Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9.
PubMed: Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.
PubMed: Radioprotective effects of black seed (Nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats.
PubMed: Terpene conjugates of the Nigella sativa seed-oil constituent thymoquinone with enhanced efficacy in cancer cells.
PubMed: Thymoquinone-induced relaxation of isolated rat pulmonary artery.
PubMed: Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa.
PubMed: Antimicrobial effect of garlic (Allium sativum).
PubMed: Multiple molecular targets underlie the antidiabetic effect of Nigella sativa seed extract in skeletal muscle, adipocyte and liver cells.
PubMed: Cellular transport of anti-inflammatory pro-drugs originated from a herbal formulation of Zingiber cassumunar and Nigella sativa.
PubMed: Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells.
PubMed: Anti bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus.
PubMed: Gastroprotective effect of an aqueous suspension of black cumin Nigella sativa on necrotizing agents-induced gastric injury in experimental animals.
PubMed: Ancient nigella seeds from Boyali Höyük in north-central Turkey.
PubMed: Effectiveness, safety, and tolerability of powdered Nigella sativa (kalonji) seed in capsules on serum lipid levels, blood sugar, blood pressure, and body weight in adults: results of a randomized, double-blind controlled trial.
PubMed: Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species.
PubMed: Effects of Nigella sativa seed extract on ameliorating lung tissue damage in rats after experimental pulmonary aspirations.
PubMed: Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats.
PubMed: Black seed, Nigella sativa, deserves more attention.
PubMed: Therapeutic effects of Nigella sativa on chronic HAART-induced hyperinsulinemia in rats.
PubMed: Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using thymoquinone - biomed 2009.
PubMed: Comparison of chemical composition and antibacterial activity of Nigella sativa seed essential oils obtained by different extraction methods.
PubMed: HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone.
PubMed: Effects of thymoquinone and selenium on the proliferation of mg 63 cells in tissue culture.
PubMed: Effect of different levels of feed added black seed (Nigella sativa L.) on the performance of broiler chicks.
PubMed: Biological activity of seed aqueous extract of Nigella sativa (L.) on germination and seedling growth of Vigna radiata (L.).
PubMed: Black cumin (Nigella sativa L.) supplementation into the diet of the laying hen positively influences egg yield parameters, shell quality, and decreases egg cholesterol.
PubMed: From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond.
PubMed: The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims: a randomized, double-blind, placebo-controlled trial.
PubMed: Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension.
PubMed: Attenuation of the development of hypercholesterolemic atherosclerosis by thymoquinone.
PubMed: Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors.
PubMed: The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures.
PubMed: Cardiac inotropic and hypertrophic effects of Nigella sativa supplementation in rats.
PubMed: The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients.
PubMed: The secret of the black seed: an ancient healing remedy for the modern healer.
PubMed: Anti-tumor properties of blackseed (Nigella sativa L.) extracts.
PubMed: A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
PubMed: Effect of Nigella sativa (Black Seed) and thymoquinone on blood glucose in albino rats.
PubMed: Assessment of cellular responses to oxidative stress using MCF-7 breast cancer cells, black seed (N. Sativa L.) extracts and H2O2.
PubMed: Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.
PubMed: An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols.
PubMed: Immunomodulatory and therapeutic properties of the Nigella sativa L. seed.
PubMed: Immunomodulating effects of black seed and oxytetracycline in pigeons.
PubMed: Nigella sativa (black seed) oil does not affect the T-helper 1 and T-helper 2 type cytokine production from splenic mononuclear cells in allergen sensitized mice.
PubMed: An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice.
PubMed: Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone.
PubMed: The effects of isolated antioxidants from black seed on the cellular metabolism of A549 cells.
PubMed: Floral costs in Nigella sativa (Ranunculaceae): compensatory responses to perianth removal.
PubMed: Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone.
PubMed: Determination of isopropylmethylphenols in black seed oil by differential pulse voltammetry.
PubMed: Nigella sativa seed extracts enhance glucose-induced insulin release from rat-isolated Langerhans islets.
PubMed: Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.
PubMed: Effects of sustained delivery of thymoqiunone on bone healing of male rats.
PubMed: Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug.
PubMed: Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats.
PubMed: Effects of Nigella sativa L. and Urtica dioica L. on selected mineral status and hematological values in CCl4-treated rats.
PubMed: Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases.
PubMed: Radical scavenging activity of black cumin (Nigella sativa L.), coriander (Coriandrum sativum L.), and niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions.
PubMed: A simple differential pulse polarographic method for the determination of thymoquinone in black seed oil.
PubMed: Thymoquinone-induced relaxation of guinea-pig isolated trachea.
PubMed: The role of black seed in the proliferation and biochemical marker levels of Hep-2 cells.
PubMed: Delayed apoptosis upon the treatment of Hep-2 cells with black seed.
PubMed: Pharmacological and toxicological properties of Nigella sativa.
PubMed: Characterization of phospholipid composition of black cumin (Nigella sativa L.) seed oil.
PubMed: Response of broiler chicks to dietary Rhazya stricta and Nigella sativa.
PubMed: Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping.
PubMed: Effects of Nigella sativa fixed oil on blood homeostasis in rat.
PubMed: Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis.
PubMed: Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection.
PubMed: High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.).
PubMed: Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone.
PubMed: The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L.
PubMed: Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats.
PubMed: The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: elucidation of the mechanism of action.
PubMed: The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea-pigs: elucidation of the mechanism(s) of action.
PubMed: Studies on the antimicrobial activity of Nigella sativa seed (black cumin).
PubMed: Modulatory effects of Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in mice.
PubMed: Sterols in the seed oil of Nigella sativa.
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