hydrastis canadensis powder
powder obtained from the herb of the goldenseal, hydrastis canadensis l., ranunculaceae
 
Notes:
a plant genus of the family ranunculaceae. members contain berberine.
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Name: hydrastis canadensis powder
CAS Number: 84603-60-1 
ECHA EC Number: 283-261-5
Category: cosmetic ingredient for skin conditioning
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
Vege Tech
O.C. Golden Seal
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for hydrastis canadensis powder usage levels up to:
 not for fragrance use.
 
Recommendation for hydrastis canadensis powder flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
Daily Med: search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 hydrastis canadensis powder
Chemidplus: 0084603601
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References:
 hydrastis canadensis powder
Pubchem (sid): 135307822
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Other Information:
Export Tariff Code: 1302.19.0000
MedlinePlusSupp: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 hydrastis canadensis
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Synonyms:
 golden seal powder
 goldenseal powder
 powder obtained from the herb of the goldenseal, hydrastis canadensis l., ranunculaceae
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Articles:
PubMed: Antioxidant and anti-inflammatory activities of berberine in the treatment of diabetes mellitus.
PubMed: Application of UPLC-QTOF-MS in MS(E) mode for the rapid and precise identification of alkaloids in goldenseal (Hydrastis canadensis).
PubMed: Ethanolic extract of the Goldenseal, Hydrastis canadensis, has demonstrable chemopreventive effects on HeLa cells in vitro: Drug-DNA interaction with calf thymus DNA as target.
PubMed: Characterization of the alkaloids in goldenseal (Hydrastis canadensis) root by high resolution Orbitrap LC-MS(n).
PubMed: Quantitative determination of alkaloids from roots of Hydrastis canadensis L. and dietary supplements using ultra-performance liquid chromatography with UV detection.
PubMed: Biosynthesized silver nanoparticles by ethanolic extracts of Phytolacca decandra, Gelsemium sempervirens, Hydrastis canadensis and Thuja occidentalis induce differential cytotoxicity through G2/M arrest in A375 cells.
PubMed: Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA).
PubMed: Phenotyping studies to assess the effects of phytopharmaceuticals on in vivo activity of main human cytochrome p450 enzymes.
PubMed: Pharmacokinetic herb-drug interactions (part 2): drug interactions involving popular botanical dietary supplements and their clinical relevance.
PubMed: Modulations of cytochrome P450 expression in diabetic mice by berberine.
PubMed: Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats.
PubMed: Analysis of goldenseal, Hydrastis canadensis L., and related alkaloids in urine using HPLC with UV detection.
PubMed: Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis).
PubMed: Synergy-directed fractionation of botanical medicines: a case study with goldenseal (Hydrastis canadensis).
PubMed: Toxicology and carcinogenesis studies of goldenseal root powder (Hydrastis Canadensis) in F344/N rats and B6C3F1 mice (feed studies).
PubMed: Extracts of Canadian first nations medicinal plants, used as natural products, inhibit neisseria gonorrhoeae isolates with different antibiotic resistance profiles.
PubMed: Hydrophobic treatment enabling analysis of wettable surfaces using a liquid microjunction surface sampling probe/electrospray ionization-mass spectrometry system.
PubMed: Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition.
PubMed: Anti-carcinogenic potentials of a plant extract (Hydrastis canadensis): I. Evidence from in vivo studies in mice (Mus musculus).
PubMed: Seasonal variation of biomass and bioactive alkaloid content of goldenseal, Hydrastis canadensis.
PubMed: The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest.
PubMed: Significant differences in alkaloid content of Coptis chinensis (Huanglian), from its related American species.
PubMed: Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni.
PubMed: Medicinal plants used in British Columbia, Canada for reproductive health in pets.
PubMed: Validation of a liquid chromatography-tandem mass spectrometric assay for the quantitative determination of hydrastine and berberine in human serum.
PubMed: Determination of hydrastine and berberine in goldenseal raw materials, extracts, and dietary supplements by high-performance liquid chromatography with UV: collaborative study.
PubMed: Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.
PubMed: Effect of homeopathic medicines on transplanted tumors in mice.
PubMed: Modulation of human cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in Caco-2 cell monolayers by selected commercial-source milk thistle and goldenseal products.
PubMed: Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line.
PubMed: Effects of herbal products and their constituents on human cytochrome P450(2E1) activity.
PubMed: Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.) 3: effect on human lens and retinal pigment epithelial cells.
PubMed: Ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in British Columbia, Canada.
PubMed: Severe hypernatremia and hyperosmolality exacerbated by an herbal preparation in a patient with diabetic ketoacidosis.
PubMed: Effects of root isoquinoline alkaloids from Hydrastis canadensis on Fusarium oxysporum isolated from Hydrastis root tissue.
PubMed: Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo.
PubMed: Thin-layer chromatography/desorption electrospray ionization mass spectrometry: investigation of goldenseal alkaloids.
PubMed: Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans.
PubMed: Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine.
PubMed: A reproductive screening test of goldenseal.
PubMed: Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts.
PubMed: In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes.
PubMed: A new glucosyl feruloyl quinic acid as a potential marker for roots and rhizomes of goldenseal, Hydrastis canadensis.
PubMed: Immunoquantitative analysis for berberine and its related compounds using monoclonal antibodies in herbal medicines.
PubMed: Chemical comparison of goldenseal (Hydrastis canadensis L.) root powder from three commercial suppliers.
PubMed: Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components.
PubMed: Antimicrobial constituents from goldenseal (the Rhizomes of Hydrastis canadensis) against selected oral pathogens.
PubMed: Method validation for determination of alkaloid content in goldenseal root powder.
PubMed: Microbial transformation of the phthalideisoquinoline alkaloid, (-)-beta-hydrastine.
PubMed: In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis.
PubMed: Micropropagation of Hydrastis canadensis: Goldenseal a North American endangered species.
PubMed: A validated high performance liquid chromatographic method for the analysis of Goldenseal.
PubMed: Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.) 1. Berberine.
PubMed: Cardiovascular actions of berberine.
PubMed: Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids.
PubMed: High-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal.
PubMed: Relaxant effects of Hydrastis canadensis L. and its major alkaloids on guinea pig isolated trachea.
PubMed: Antioxidants in medicinal plant extracts. A research study of the antioxidant capacity of Crataegus, Hamamelis and Hydrastis.
PubMed: An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures.
PubMed: A convenient method for the determination of the quality of goldenseal.
PubMed: Berberine.
PubMed: Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis.
PubMed: Analysis of isoquinoline alkaloids in medicinal plants by capillary electrophoresis-mass spectrometry.
PubMed: Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifendine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2.
PubMed: Canadinic acid: an alkaloid from Hydrastis canadensis.
PubMed: Evaluation of traditional plant treatments for diabetes: studies in streptozotocin diabetic mice.
PubMed: Berberine sulfate inhibits tumor-promoting activity of teleocidin in two-stage carcinogenesis on mouse skin.
PubMed: Thin layer chromatography and U. V. spectrphotometry of alcoholic extracts of Hydrastis canadensis.
PubMed: [Spectrometric determination of the hydrastin content of the rhizome of Hydrastis canadensis L].
PubMed: [Study of the effect of termperature and time on oxidation of hydrastine to hydrastinine in the presence of air oxygen an steam in fluid extract and in rhizoma of Hydrastis canadensis].
PubMed: [Chromatographic-fluorometric micromethod for assays of hydrastine and hydrastinine in the liquid extract and rhisome of Hydrastis canadensis L].
PubMed: [Separation of berberine, hydrastine and hydrastinine from rhizomes of Hydrastis Canadensis and from the liquid extract].
PubMed: [The use of countercurrent partition for the separation and determination of alkaloids of Hydrastis canadensis].
PubMed: [Note on the hydrastine content in cultivated Hydrastis canadensis L].
PubMed: The Treatment of Haemorrhage in Fibro-Myomata by Hydrastis Canadensis.
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