withania somnifera leaf
ashwagandha leaf
 
Notes:
None found
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Name: withania somnifera leaf
CAS Number: 90147-43-6 
ECHA EC Number: 290-434-9
Category: information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Pride International
Ashwaganda
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for withania somnifera leaf usage levels up to:
 not for fragrance use.
 
Recommendation for withania somnifera leaf flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
AIDS Citations: Search
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 withania somnifera leaf
Chemidplus: 0090147436
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References:
 withania somnifera leaf
Pubchem (sid): 135338547
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 ashwagandha leaf
Search Trop  Picture
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Synonyms:
 ajagandha leaf
 ashwagandha leaf
winter cherry leaf
indian ginseng leaf
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Articles:
PubMed: Withaferin A modulates the Spindle Assembly Checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines.
PubMed: Glioprotective Effects of Ashwagandha Leaf Extract against Lead Induced Toxicity.
PubMed: Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases from Withania somnifera (L.) Dunal.
PubMed: Sterol partitioning by HMGR and DXR for routing intermediates toward withanolide biosynthesis.
PubMed: Characterization of Withania somnifera leaf transcriptome and expression analysis of pathogenesis-related genes during salicylic acid signaling.
PubMed: WsSGTL1 gene from Withania somnifera, modulates glycosylation profile, antioxidant system and confers biotic and salt stress tolerance in transgenic tobacco.
PubMed: Photosensitized synthesis of silver nanoparticles using Withania somnifera leaf powder and silver nitrate.
PubMed: Copper-stress induced alterations in protein profile and antioxidant enzymes activities in the in vitro grown Withania somnifera L.
PubMed: Investigation of heavy metals in frequently utilized medicinal plants collected from environmentally diverse locations of north western India.
PubMed: Dynamics of withanolide biosynthesis in relation to temporal expression pattern of metabolic genes in Withania somnifera (L.) Dunal: a comparative study in two morpho-chemovariants.
PubMed: Distribution of withaferin A, an anticancer potential agent, in different parts of two varieties of Withania somnifera (L.) Dunal. grown in Sri Lanka.
PubMed: Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.
PubMed: De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis.
PubMed: Effect of plant secondary compounds on in vitro methane, ammonia production and ruminal protozoa population.
PubMed: Methanolic extracts of Withania somnifera leaves, fruits and roots possess antioxidant properties and antibacterial activities.
PubMed: Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences.
PubMed: Optimization of elicitation conditions with methyl jasmonate and salicylic acid to improve the productivity of withanolides in the adventitious root culture of Withania somnifera (L.) Dunal.
PubMed: Carbohydrate and elicitor enhanced withanolide (withaferin A and withanolide A) accumulation in hairy root cultures of Withania somnifera (L.).
PubMed: Evaluation of antimicrobial efficacy of flavonoids of withania somnifera L.
PubMed: Cloning and characterization of 2-C-methyl-D-erythritol-4-phosphate pathway genes for isoprenoid biosynthesis from Indian ginseng, Withania somnifera.
PubMed: Application of HR-MAS NMR spectroscopy for studying chemotype variations of Withania somnifera (L.) Dunal.
PubMed: Metabolic characterization of Withania somnifera from different regions of India using NMR spectroscopy.
PubMed: Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite.
PubMed: Management of Parthenium hysterophorus (Asteraceae) by Withania somnifera (Solanaceae).
PubMed: Reversal of Cadmium-induced Oxidative Stress in Chicken by Herbal Adaptogens Withania Somnifera and Ocimum Sanctum.
PubMed: Comprehensive metabolic fingerprinting of Withania somnifera leaf and root extracts.
PubMed: Antioxidant effect of dietary supplement Withania somnifera L. reduce blood glucose levels in alloxan-induced diabetic rats.
PubMed: Agrobacterium tumefaciens-mediated transformation of Withania somnifera (L.) Dunal: an important medicinal plant.
PubMed: Generation and analysis of expressed sequence tags from leaf and root of Withania somnifera (Ashwgandha).
PubMed: Molecular insight into the immune up-regulatory properties of the leaf extract of Ashwagandha and identification of Th1 immunostimulatory chemical entity.
PubMed: Hypoglycaemic and hypolipidaemic effects of Withania somnifera root and leaf extracts on alloxan-induced diabetic rats.
PubMed: Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease.
PubMed: Studies on leaf spot disease of Withania somnifera and its impact on secondary metabolites.
PubMed: Establishment of Withania somnifera hairy root cultures for the production of withanolide A.
PubMed: Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection.
PubMed: Withanolide induces apoptosis in HL-60 leukemia cells via mitochondria mediated cytochrome c release and caspase activation.
PubMed: In Vivo antimalarial activity of aqueous extracts from Kenyan medicinal plants and their chloroquine (CQ) potentiation effects against a blood-induced CQ-resistant rodent parasite in mice.
PubMed: Inhibition of aflatoxin B production of Aspergillus flavus, isolated from soybean seeds by certain natural plant products.
PubMed: Genetically modified hairy roots of Withania somnifera Dunal: a potent source of rejuvenating principles.
PubMed: Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha.
PubMed: Microorganisms asssociated with Withania somnifera leaves.
PubMed: Positive growth responses of the medicinal plants Spilanthes calva and Withania somnifera to inoculation by Piriformospora indica in a field trial.
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